Sentences with phrase «of cellular function»

This means that there will be some kind of cellular function.

Overmethylators tend to have an underactive DNA «transcription» process, whereas undermethylators have an overactivity of cellular function.

«We're just beginning to appreciate that much of cellular function happens at short distances, between nearly touching organelles,» says Dr. Hajnoczky.

Modern cells use RNA to make proteins, the workhorses of cellular function, but RNA likely preceded both proteins and DNA.

In humans, stuttering has long been linked to a mutation in the «housekeeping» gene Gnptab, which maintains basic levels of cellular function.

Following the discovery of non-coding RNA, it has become more and more recognized that different types of RNA are functionally active and regulate almost all aspects of cellular function.

Rapamycin, which is an inhibitor of the mammalian target of rapamycin (mTOR) signaling pathway, has a variety of cellular functions and is known to possess both immunosuppressant and anti-tumor properties.

Composed of a vast array of different cells, the brain depends on a complex orchestra of cellular functions to carry out its tasks.

Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.

Proteins are responsible for the vast majority of the cellular functions that shape life, but like guests at a crowded dinner party, they interact transiently and in complex networks, making it difficult to determine which specific interactions are most important.

Interference with a host of cellular functions tested and synergistic activities with a wide range of other drugs is best explained by direct interaction with various DNA sequences and general interference with replication and transcription, except for some effects exerted by binding to tubulin.

The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation, cell communication, cell adhesion, cell - cycle regulation, the control of gene expression, and protein degradation.

This helps the lymphatic system fight infection, destroy cancerous cells, and dispose of the toxic waste products of cellular functioning.

Potassium is necessary for a whole slew of cellular functions, including allowing muscles to contract (and your heart is very much a muscle!)

When incorporated into the cell membranes of the body, these omega - 3 and omega - 6 fatty acids function as precursors for eicosanoids that control a host of cellular functions and responses.

This feature allows hand - off of cellular functions to Wi - Fi networks without using any additional apps.

Not exact matches

Are our bodies made up of cellular cosmologies where science interprets the cellular insides to be made up of biomechanical shapes doing all the needed functions to sustain our body's welfares?

Although the work is done in the context of a more general problem — the effect of environmental electromagnetic fields upon cellular functions — Adey is also concerned with the question of how brain waves might play a role in normal brain function.

The heart is a great source of CoQ10, which is essential for normal cellular function and heart health.

Numerous different other functions that make the child infant stroller a great deal much less challenging consist of storeroom location pockets for techniques, cellular phone, along with playthings.

Some autopsy data shows that infants of smokers have signs of established hypoxic - ischemic cellular injury in the brain and the heart which probably occurred in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous system function and lead to poor temperature control, and poor heart rate and respiration control.

Although much of the cellular and sub-cellular functions of the human brain remain unknown, the insights we currently have paint a more nuanced understanding of human nature, which in turn helps shape our understanding of politics, IR theory, and global order.

Vitamin B12 is necessary for the body's vital functions, including the production of red blood cells and cellular metabolic energy.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

- The U.S. National Science Foundation funds a range of relevant biological science areas, including biomolecular dynamics, structure, and function, as well as cellular processes

Close collaboration between the Pasteur Institute and Inria, taking the form of the InBio join research group, whose aim is to develop a methodological framework for achieving a quantitative understanding of the functioning of cellular processes, is the perfect illustration of the value of interdisciplinary research combining experimental approaches with methodological developments.

This junction is important because of the roles it plays in cellular communication, nutrient exchange and absorption, and other skin functions.

The idea is the mitochondria — the cellular energy generators — in these primitive cells function better than those in the eggs of women struggling to conceive.

«Lipids play a vital role in cellular function, because they form the membranes that surround each cell and many of the structures inside of it,» Quinlivan said.

The affected mitochondria could no longer provide the synapses with enough energy, which ultimately prevented the synapses from functioning — providing the first direct link between cellular injury caused by amyloid protein and the characteristic breakdown of neuronal communication that occurs in Alzheimer's patients.

Allan Jacobson, Ph.D., of the University of Massachusetts Medical School and co-founder of PTC Therapeutics, the company that developed ataluren, and David Bedwell, Ph.D., professor of the UAB Department of Biochemistry and Molecular Genetics, have sought to understand precisely how ataluren allows the ribosome, the machinery of cellular protein synthesis, to skip over these inserted stop signs and produce proteins that have normal or near - normal function.

These data demonstrate that in RNA's with very different cellular functions, there are domains with similar structural and functional properties and that there is a nucleotide in M1 RNA that affects the site of cleavage by the enzyme.

The organizers, including researchers from Frankfurt, expect that many cellular functions of membrane lipids will be revisited from a new perspective and that it will be possible to support hormone - producing cells in a more targeted manner.

HIF - 1 senses reduced oxygen levels and triggers many changes in cellular function, including a changed metabolism and sending signals for the formation of new blood vessels.

«Transplanted hematopoietic stem cells reverse damage caused by neuro - muscular disorder: In mouse model of Friedreich's ataxia, a single infusion measurably restored normal cellular functions.»

Although no functions could be assigned to three of the proteins, bioinformatics analysis suggested that the remainder are involved in a wide range of biological processes, including reproduction, cellular metabolic processes, multicellular organismal growth, developmental processes, growth, locomotion, response to stimuli, localization and biological regulation.

A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions.

At first it was thought that only functioned as cellular debris warehouses but in recent years has been that could have an important role as a messenger between cells of the body and now many groups focus their research on the role that could be played exosomes in various diseases, including cancer.

Clinicians are well - versed with the human body and the delicate use of surgeries and drugs, while scientists understand the intricacies of how the body functions at the molecular and cellular level,» he explains.

This enabled the researchers to detect mutations in three genes — GNPTAB, GNPTG, and NAGPA — involved in the function of lysosomes, the cellular sacs where debris gets recycled.

Hackermüller suspects that non-coding RNAs have an important function at the epigenetic level, for example as a type of cellular long - term memory: «This could also explain why the health effects caused by exposure to hazardous environmental substances often do not emerge until years later.»

RNA, widely known as a cellular messenger that makes proteins and carries out DNA's instructions to other parts of the cell, is now understood to perform sophisticated chemical reactions and is believed to perform an extraordinary number of other functions, at least some of which are unknown.

Steitz shared the 2009 chemistry Nobel for his elegant elucidation of the three - dimensional structure and detailed function of the ribosome, the cellular organelle charged with the actual production of proteins as per the instructions of the genetic code.

Previous studies have linked telomeres to the function of mitochondria (essential cell organelles that act as cellular power plants) and vice versa.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

Kolodner describes the mismatch repair genes as performing the «cellular equivalent of a spellchecking function».

«Laminins function as attractive chemical cues for haptotaxis of axonal growth cones,» explains NAIST Prof. Naoyuki Inagaki, whose lab studies how forces are generated in the cellular microenvironment to create directed axonal migration.

The mice had improved metabolic functions as well, such as cholesterol levels, dopamine signaling and mitochondrial activity (an indicator of cellular energy production).

The researchers developed a computational framework to determine the structure of protein interaction networks in each sample and infer which genes performed different cellular functions within these networks.

But a string of recent discoveries indicates that a class of RNA molecules called small RNAs are actually in charge of many cellular functions.