Sentences with phrase «of cellular replication»

Not exact matches

A combination of circumstances induced me to leave India and enroll in the graduate program in what was then the department of cellular and developmental biology at the University of Arizona, Tucson, in the U.S. My Ph.D. supervisor, Neil Mendelson, had been a well - known name in DNA replication and cell division in Bacillus subtilis, but by the time I had joined his lab, his interest had decidedly shifted to cell shape determination.

The rules of the game were laid down by mathematician John Conway in 1970, but cellular automata first took off in the 1940s when the late mathematician John von Neumann suggested using them to demonstrate self - replication in nature.

Previous research had shown that Topisomerase II was involved in earlier cellular processes like DNA replication, and the enzyme was still detectable even during later phases of meiosis.

Previous studies in the lab showed that once HCMV is inside the cell, it quickly becomes latent by entering the cell's nucleus and co-opting a cellular protein called Daxx — part of the intrinsic immune system — to shut down its own replication, the process of reproducing its genetic material to make more copies of itself.

The consistent segregation of these regions, in the same way in every cell, suggests that these processes could drive chromosome and genome folding and thus regulate important cellular events such as DNA replication and cell division.

Thus, the act of responding to cellular genome breaks inactivates the host's defenses to viral replication.»

Interference with a host of cellular functions tested and synergistic activities with a wide range of other drugs is best explained by direct interaction with various DNA sequences and general interference with replication and transcription, except for some effects exerted by binding to tubulin.

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis.

The damage that it will repair is the one that is causal in senenscence of DNA pathway (such x-ray radiation causing senescence) and oncogenic activated senescence; but not of the type of replicative senescence (that's the domain of telomeres / telomerase / sub-telomeres and epigenetics) and cellular replication / proliferation.

The scope of the journal encompasses all of «traditional» molecular biology (including DNA replication, recombination and repair, gene expression, RNA processing, translation, and protein folding, modification, and degradation) as well as studies of the molecular interactions and mechanisms that underlie basic cellular processes.

Characterizing the molecular pathways regulating genomic stability at damaged replication forks in HR - deficient cancers will increase our understanding of the cellular response to replicative stress, and in the same time, potentially allow the identification of new predictors (biomarkers) of chemo - sensitivity / resistance in these tumors (Figure 2B).

The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations - an extended version of a classic metabolic map, in a single consistent data model.

Enzymes are essential for energy production, synthesis of biological molecules, gene repair and replication, maintenance of cellular and tissue structural integrity, and normal physiological function.

Zinc plays a vital role in the health of the body by supporting cellular metabolism (wound healing, cellular renewal, DNA and RNA replication) and immune function.

Interferons may have multiple mechanisms of action in viral diseases for example modulating cellular and immune functions and impairing virus replication.