Sentences with phrase «of cellular responses»

Analysis of cellular responses to free radicals: focus on exercise and skeletal muscle.

To gain a deeper understanding of the cellular response of the two neurotoxins, the researchers applied global quantitative proteomics at the U.S. Department of Energy's national user facility — the Environmental Molecular Sciences Laboratory — and microarrays at UCLA to assay the protein and gene levels, respectively, for both neurotoxins.

«We found dysregulated expression in a suspect gene complex which adds to evidence that PMDD is a disorder of cellular response to estrogen and progesterone,» explained Peter Schmidt, M.D. of the NIH's National Institute of Mental Health, Behavioral Endocrinology Branch.

Dr. Subramaniam is head of database developments under The Alliance for Cellular Signaling, a multi-institution, multidisciplinary project, utilizing a multitude of high throughput approaches to obtain context - specific knowledge of cellular response to input.

Cellular immunity is critical for long - lived antibody responses, but detailed analysis of cellular responses requires fresh blood samples, thus we are currently planning to enroll new cohorts in east Africa to address this question.

On the other hand, histidine kinases allow bacteria, plants, and fungi to sense and respond to their environment, regulating a number of cellular responses such as osmoregulation, chemotaxis, sporulation and microbial pathogenesis (37).

Live cell assays constructed with genetically encoded, fluorescent biosensors can provide significant advantages over endpoint assays measured in cell lysates because functional information about the timing and location of cellular responses can be monitored in cells that are relevant to disease.

A major challenge that will be addressed in the second phase of LINCS is to optimize the combinations of cell types, perturbations and measurements of cellular responses to address a wider range of basic biological and disease - related problems than was possible in the program's initial pilot stage, said Alan Michelson, M.D., Ph.D., senior investigator, Laboratory of Developmental Systems Biology, NHLBI, and co-chair of the NIH LINCS Project Implementation Team.

These glands are charged with producing cortisol (which ultimately promotes insulin resistance or the lack of cellular response to insulin) and fight - or - flight chemicals that can get your heart racing and ratchet up anxiety.

She says the research has the potential to expand understanding of cellular responses to the space environment to improve astronaut health, safety and performance.

Characterizing the molecular pathways regulating genomic stability at damaged replication forks in HR - deficient cancers will increase our understanding of the cellular response to replicative stress, and in the same time, potentially allow the identification of new predictors (biomarkers) of chemo - sensitivity / resistance in these tumors (Figure 2B).