Sentences with phrase «of changes in their metabolism»

Human reproduction carries with it a multitude of changes in metabolism, hormone regulation, circulation, and liver function.

However, in adults (because of changes in metabolism) this is a very critical point.

It is dangerous for cats to lose weight too quickly because this predisposes them to the development of hepatic lipidosis, a potentially fatal liver disease whereby fat is deposited within the liver as a result of a change in metabolism during fasting.

The rapid onset of changes in their metabolism as a result can lead to a shock - like state.

Not exact matches

Influence of intermittent fasting and high - fat diet on morphological changes of the digestive system and on changes of lipid metabolism in the laboratory mouse

The April 2007 issue of Annals of Nutrition and Metabolism includes an article on the positive changes in inflammatory markers brought about by the intermittent fasting Muslims undergo during Ramadan.

Hormone changes due to induced abortion may indeed be related to breast cancer, but there are other known causes of hormone changes that we should worry about, including the widespread use of chemical contraceptives, fertility drugs that cause hormone surges, increased obesity and fat content in the diet that change the body's estrogen metabolism, and last but not least, chemical contaminants in the environment that mimic estrogen....

Such a low level can decrease the likelihood of unintended changes in plant metabolism and composition.

Your metabolism completely changes when in ketosis and so the number of calories is almost irrelevant.

During the first six months of life, explains Michael Goodstein, neonatologist and director of the York County Cribs for Kids Program at York Hospital in York, PA, a baby experiences rapid brain growth and developmental changes that affect sleep patterns, cardiorespiratory control, metabolism, and physical ability.

A study published yesterday in Nature Climate Change showed that early exposure to high levels of CO2 during the larval stage of development had significant negative effects on the fish's size, metabolism and ability to sense threats in their environment.

But something did change about 800 million years ago, and cyanobacteria and other minute organisms in continental margin ecosystems got more phosphorus, the backbone of DNA and RNA, and a main actor in cell metabolism.

Our study shows that after that early programming state, after weaning, and after the lactation period, when we introduced a new type of diet it changed the epigenome in a way that actually affects metabolism and potentially will reduce some of the damage caused by an early - life high - fat exposure,» Pan says.

The investigators noted that the baseline risk of major malformations is 3 percent and of cardiac malformations is 1 percent; however, any increase in risk is significant, especially when considering that the benefit of using selective serotonin reuptake inhibitors during pregnancy — when changes in metabolism cause the drugs to be cleared from the body at a faster rate — is debatable.

The roles that white fat and brown fat play in metabolism is well documented, but new research published in the January 2015 issue of the FASEB Journal presents a new wrinkle: each type of fat may change into the other, depending on the temperature.

HIF - 1 senses reduced oxygen levels and triggers many changes in cellular function, including a changed metabolism and sending signals for the formation of new blood vessels.

Of the genes undergoing the strongest evolutionary change, many are involved in body shape and organ development, metabolism, venom production and the sense of smell (PNAS, DOI: 10.1073 / pnas.1314475110Of the genes undergoing the strongest evolutionary change, many are involved in body shape and organ development, metabolism, venom production and the sense of smell (PNAS, DOI: 10.1073 / pnas.1314475110of smell (PNAS, DOI: 10.1073 / pnas.1314475110).

If the type of incoming material changes rapidly — say, a surge in video traffic in the Internet's case, or a new food source for the E. coli — the system can process that material without having to retool its entire metabolism to cope.

However, only the mice that consumed black tea extract had an increase in a type of bacteria called Pseudobutyrivibrio, which could help explain the difference between how black tea and green tea change energy metabolism.

The researchers linked the excess weight and changes in metabolism to epigenetic modifications that reduce expression of the gene for adiponectin — a hormone that helps regulate several metabolic processes, including glucose regulation.

«Both forms of exercise improved the whole body's insulin sensitivity equally efficiently and most likely, we would have seen a change also in the brain's metabolism after moderate training if the exercise period would have been longer.

The struggle to escape obesity takes more and more Americans to a surgeon's door, in search of bariatric surgery they hope will change their metabolism, help them lose pounds and cut their risk of weight - related health issues.

«These tumors are genetically very complex, and we demonstrated this by showing just the sheer volume of copy number changes, and that there are multiple clones in a single metastases tumor, and changes in metabolism that reflects the tumor's ability to adapt.»

Aware that cancers rewire their metabolism in ways that could change the epigenome and that distant metastases in pancreatic cancer naturally spread to organs fed by a sugar - rich blood supply, the researchers wondered if the tumor cells had altered the way they use the basic form of sugar, glucose.

The surgery also changes the community of bacteria living in a patient's gut, which may drive weight loss and could even alter metabolism.

Weak muscle contractions, sustained over a long period of time — as in during a bike ride — change proteins, mainly ones involved in metabolism.

While researching the molecular causes of heart failure and new ways to treat it, a Charité - based working group, led by Prof. Dr. Ulrich Kintscher, found that changes in adipose (fat) tissue lipid metabolism affect disease development.

Astronauts already provide blood and urine samples before and after flight so scientists can examine changes to their metabolism, but Dragon's cold stowage capability will allow scientists to examine samples returned in the middle of the crew's mission.

Genes with mammoth - specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Arctic.

This bank of living tumour cells allowed the team to study not only the genetics of the cells, but also how genetic mutations in the mitochondria — which drive energy production in the cell — caused changes in the cell's metabolism.

When the researchers added oligosaccharides purified from whey to the Malawian diets of mice with microbes from a severely malnourished infant, the mice grew more muscle, bigger bones, and had quite «dramatic changes» in brain and liver metabolism, Gordon says.

Romain Barrès, who studies the genetics of metabolism at the University of Copenhagen, wanted to see whether there was evidence of such epigenetic changes in human sperm.

This kind of «binge — starvation» cycle has been linked to changes in metabolism, insulin resistance and, ultimately, increases in BMI.

While for most individuals, there will be no long - term consequences, in some the infection may leave genetic scars and change the metabolism of these cells,» explained Wulf.

It's becoming clear and clearer as people look at different stages of the plant's growth and in different habitats growing next to other plants that the stressors in the environment can really change the chemistry; because most of the medicinal compounds in the plants are what are called secondary compounds, so they are not things essential to the metabolism of the plant like sugar and water and ATP for energy and DNA.

«I'm already changing my teaching slides» about the functions of bones, comments Jennifer Westendorf, an associate professor of orthopedic surgery at the Mayo Clinic in Rochester, Minn. «Now we can add that [the skeleton] affects energy metabolism as well,»

However, the precise nature of that role is undergoing a visible change, not only because of the new synthetic methods and technologies now available to the synthetic and medicinal chemist, but also in several key areas, particularly in drug metabolism and chemical toxicology, as chemists deal with the ever more rapid turnaround of testing data that influences their day - to - day decisions.

Changes in these proteins have a great influence on drug efficacy and side effects since they are responsible for the metabolism and transport of many drugs, and are also affected by changes in the intestinalChanges in these proteins have a great influence on drug efficacy and side effects since they are responsible for the metabolism and transport of many drugs, and are also affected by changes in the intestinalchanges in the intestinal flora.

The altered methionine metabolism leads to activation of oncogenes, while the changes in tryptophan metabolism shield GBM cells from detection by immune cells.

The significant impact of this change in dietary richness on human health is the topic of an insightful perspective in Molecular Metabolism by Mark Heiman, MicroBiome Therapeutics and Frank Greenway, Pennington Biomedical Research Center.

After 12 weeks on the high sugar diet, the men with a high level of liver fat — a condition known as non-alcoholic fatty liver disease (NAFLD)-- showed changes in their fat metabolism that are associated with an increased risk of cardiovascular disease, heart attacks and strokes.

Not only were levels of metabolic compounds different, but the expression of certain genes involved in metabolism was turned up, and the epigenome of the cells — molecular markers on DNA that change gene expression on a broader scale — was altered.

This study shows that the effect of mitochondrial dysfunction on nuclear DNA methylation is mediated by changes in methionine and polyamine metabolism.

Environmental factors interact with the different subgenomes to modify the transcription of their component genes and to modulate the translation of protein products and their posttranslational modification, yielding changes in protein and cellular function and metabolism, and defining an intermediate phenotype.

When stromal signaling molecules — isolated from patients or generated in the lab — were present, the metabolism of pancreatic cancer cells changed, the researchers found.

The overall aim of this project is to examine the role of tissue - specific changes in mRNA translation in response to dietary restriction (DR) and to examine their role in modulating metabolism, muscle activity and healthspan using D. melanogaster.

Furthermore, clipping or genetically ablating wings from flies prevented the protective effects of DR on lifespan, demonstrating a critical role for the observed increase in physical activity in determining lifespan upon DR. To further elucidate the mechanisms by which changes in DR mediates changes in metabolism we are identifying and characterizing various tissue specific modulators of fat metabolsm

But in the other two types of mice, changes in the microbiome did not bring these positive changes in metabolism.

Angiotensin II receptor type 1 (Agtr1a): Lowering Agtr1a protein levels protects mitochondrial function and modestly extends life in mice, though as for many of these methods of somewhat slowing aging there are probably many other changes to the operation of metabolism that are as yet unexplored.

«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune cells change during cardiovascular disease progression in humans,» says Hedrick.