Sentences with phrase «of changes over the years including»

Ramon's Village Resort has seen a lot of changes over the years including in late 2009 when Richard and Gina spent $ 1,000,000 USD to spruce the place up a bit.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

She officially took MacArthur's helm last year after over a decade as a top exec there, and has moved with bold decisiveness to streamline the foundation and focus its resources on some of the biggest challenges of our time, including climate change and mass incarceration.

Forward - looking statements may include, among others, statements concerning our projected adjusted income (loss) from operations outlook for 2018, on both a consolidated and segment basis; projected total revenue growth and global medical customer growth, each over year end 2017; projected growth beyond 2018; projected medical care and operating expense ratios and medical cost trends; our projected consolidated adjusted tax rate; future financial or operating performance, including our ability to deliver personalized and innovative solutions for our customers and clients; future growth, business strategy, strategic or operational initiatives; economic, regulatory or competitive environments, particularly with respect to the pace and extent of change in these areas; financing or capital deployment plans and amounts available for future deployment; our prospects for growth in the coming years; the proposed merger (the «Merger») with Express Scripts Holding Company («Express Scripts») and other statements regarding Cigna's future beliefs, expectations, plans, intentions, financial condition or performance.

Over the course of the past year, there have been many changes with Loyal3, including the elimination of... [Read more...]

But this time there has been a mad rush to the «transparency and accountability» altar and because of a Senate spending scandal and a $ 90,000 payoff we may be heading to the type of real change so many, including this newspaper, have pushed for over the years.

While the program has undergone many changes over the year, including raising loan limits, the FHA has been successful in making homeownership a reality for a greater portion of the population.

For over 50 years, regardless of the political environment or changes in the economy, GLIDE has stood with the most vulnerable, including poor people, those with illness, people of color, immigrants, as well as all families and children fleeing war and oppression.

«Despite the many changes that have taken place in American society and culture over the past 30 years, including new discoveries in biological and social science, there has been virtually no sustained change in Americans» views of the origin of the human species since 1982,» wrote Gallup's Frank Newport.

It should be a spring board for change, deep relection, and ultimately growth if we are willing to look seriously at what went wrong including acknowledging that some things are out of our hands... beyond our control and then move on... because that moment in time just isn't worth the energy over the years to keep it alive in our heart, souls and mind.

All religions including Islam, Christianity and Judaism disagree on everything, at least they agree on one thing, that this dude is going to hell... And the funny part is that you can comment all you can and convince all the people you want, but the reality will never change,,, we are all going to die,, I hope that we all agree on that at least,, and all Abrahamic religions over the last 3000 years at least call for unity of God and his Existence...

But my understanding of virtually every other aspect of my faith (including the implications of the cross) has changed dramatically over the years.

I worked all across Asia including China extensively for 2 years, (from the UK) only when I'd eventually had enough and changed jobs did I realise I'd lost over a stone in weight due to all of the above.

Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...

What's more, the concept of which foods offer an appropriate complement to the diet of a breastfed infant as well as the food environment, including a booming baby food industry, have changed dramatically over the past 50 years, Turner - Maffei pointed out.

Visitors can also see how maple sugaring has changed over the years through a Maple scavenger hunt and demonstrations of different tapping techniques, including traditional Native American methods, early 19th - century New England techniques, 20th century metal buckets, and contemporary tubing.

Publication of the Purdue study sent shock - waves reverberating through the football world, with the findings cited by concussion experts calling on youth sports organizations to take more aggressive action to minimize exposure to RHI, including sub-concussive blows, by changing the way contact and collision sports are played and practiced, and reducing the amount of brain trauma a child incurs by limiting the number of hits they sustain in a sports season, over the course of a year, and during a career.

-- Climate change could impact many Bay State birds — including familiar species such as the Black - capped Chickadee — over the next 30 - 50 years, according to Mass Audubon's State of the Birds: Massachusetts Birds and Our Changing Climate.

Climate change could impact many Bay State birds — including familiar species such as the Black - capped Chickadee — over the next 30 - 50 years, according to Mass Audubon's State of the Birds: Massachusetts Birds and Our Changing Climate.

Moreover, this strict amendment process has not excessively impeded constitutional change, as it has allowed for many significant constitutional amendments over the nation's history, including the Bill of Rights and Amendments concerning the income tax, the direct election of senators, the two term presidency, and the right to vote of women and 18 year olds.

The bulk of the report focuses on changes to be made over the next 10 years, including criminal justice reforms aimed at lowering the number of people in city jails.

Cuomo is tying much of the increase to approval of his education policy changes in this year's budget, including a new teacher evaluation system, addressing failing schools by having them taken over by a state monitory and a strengthening of charter schools.

Meanwhile, Catholic bishops have spent on average $ 300,000 a year lobbying lawmakers in New York on a variety of topics, including against passage of the Child Victims Act, which would change the statute of limitations on civil and criminal cases of child sexual abuse and allow victims a one - year window to sue over potentially decades - old allegations.

Nirmala Kannankutty of the National Science Foundation's Division of Graduate Education explored similarly striking changes in the demography and size of the graduate student population, which now includes many more women and noncitizens, over the past 40 years.

Based on modeling results by the National Oceanic and Atmospheric Administration (NOAA), which predicted that Pacific Ocean temperatures would rise by 1 degree Celsius (2 degrees Fahrenheit) over the next 50 years, a Canadian and U.S. team of scientists examined the distributional changes of 28 species of fish including salmon, herring, certain species of sharks, anchovies, sardines and more northern fish like pollock.

Even the groups we came to know as Eskimo — which include the Inupiat and the Yupiks of Alaska, the Canadian Inuit and Inuvialuit, Inuit Greenlanders, and the Siberian Yupiks — have probably seen more changes in their diet in a lifetime than their ancestors did over thousands of years.

Though our published validation work did not include use of the scale before and after a science communication intervention, additional pilot work has indicated that the scale is sensitive enough to detect change in self - efficacy over a year - long training intervention.

Results demonstrate important changes in students» drinking during the calendar year, including expected large increases during the month of a one - day festival, large decreases over the summer, and resumption of relatively high quantities upon return to school.

A few of the main points of the third assessment report issued in 2001 include: An increasing body of observations gives a collective picture of a warming world and other changes in the climate system; emissions of greenhouse gases and aerosols due to human activities continue to alter the atmosphere in ways that are expected to affect the climate; confidence in the ability of models to project future climate has increased; and there is new and stronger evidence that most of the warming observed over the last 50 years is attributable to human activities.

The increased use of synthetic chemicals, including pesticides and pharmaceuticals to attack unwanted organisms, has outpaced the rates of change in rising atmospheric CO2 concentrations and other agents of global environmental change over the past 45 years, a new Duke - led analysis reveals.

Things have started to change in Flint, but fixing its water system will take years, and its citizens will need continued support in many areas — including nutrition, health care and education — to manage the effects of lead poisoning over the coming decades.

A number of theories have been developed over the years to explain more recent extinctions such as those at the end of the last ice age, including human hunting, climate change, disease, and even a cosmic impact such as an asteroid or comet.

Over the past few years, several US states and local school boards have introduced measures that would mean teachers must include the views of those who are sceptical of a human influence on climate change in science lessons.

«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune cells change during cardiovascular disease progression in humans,» says Hedrick.

A: There have been many negative things said about eggs over the years and their relationship to having high cholesterol levels in the body, but recently the official position has changed and most dietary recommendations include eggs as part of a healthy diet.

Including coconut oil in our regular diet was one of many changes I've made in our family's nutrition over the past two years, so my claim is certainly not backed by empirical data... but the coconut oil surely isn't hurting!

He had been a huge meat eater and lover of all animal carcasses, once diagnosed completely changed to a vegan diet — no oils, no fish, no chicken, no red meat, no dairy which included eggs, no fat in products over 2 grams and became completely diabetic and cancer free within months — that was 3 years ago and still free....

The report looks at three main areas of change over the next 20 years that could re-shape the online dating world: wearable technology, the rise of everyday smart technology and the smart home, and the beginning of the smart era, including smart dating.

A number of prominent Conservative MPs on Theresa May's Cabinet, including Liam Fox and David Davis, have been vocal proponents of grammar schools, and Education Secretary Justine Greening has said that the government should be «open minded» to the idea of new grammar schools as the education landscape has changed over the last few years.

To gain a better understanding of these difficulties, the Suárez - Orozcos conducted a study looking at three different levels of engagement including behavioral, cognitive, and relational to assess changes in immigrant children's performance over five years.

It is for all these reasons and more that President Barack Obama signed the Healthy, Hunger - Free Kids Act of 2010 on December 13, 2010, a law that will not only change the nutritional guidelines of the 65 - year - old National School Lunch Program, but will also provide the program's first noninflationary budget increase in more than three decades; a total of $ 4.5 billion over 10 years, which includes an additional 6 cents per meal, per child.

Hess's second case study focuses on the five - year - old voucher plan in Cleveland, where he finds that the potential benefits of choice and competition were neutralized by multiple factors, including frequent changes in leadership, the state's move to take over the city's schools, the modest size of the vouchers (only $ 2,250), and the existence of strong unions.

We included administrative data from teacher, parent, and student ratings of local schools; we considered the potential relationship between vote share and test - score changes over the previous two or three years; we examined the deviation of precinct test scores from district means; we looked at changes in the percentage of students who received failing scores on the PACT; we evaluated the relationship between vote share and the percentage change in the percentile scores rather than the raw percentile point changes; and we turned to alternative measures of student achievement, such as SAT scores, exit exams, and graduation rates.

Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight lines Use the idea that light travels in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram

For over 20 years, the National Curriculum has been revised and over the next couple of years there are a number of changes to be put in place, including some changes that have already happened.

At the behest of Democratic Gov. Phil Bredesen, lawmakers held two special legislative sessions over the last year on education to enact a series of Race to the Top - related changes that included making the state's cap on charter schools less prohibitive and overhauling teacher evaluations.

Over the past 15 years, George has participated in numerous leadership development programs including the Philadelphia Social Change Leaders Program, LEAD City Year, Comcast University's Fundamentals of Leadership Program and LeadBoston.

Conduct an extensive review of the accountability system, including the multiple changes that have been implemented over the last several years.

These include: · Use of instructional programs and curricula that support state and district standards and of high quality testing systems that accurately measure achievement of the standards through a variety of measurement techniques · Professional development to prepare all teachers to teach to the standards · Commitment to providing remedial help to children who need it and sufficient resources for schools to meet the standards · Better communication to school staff, students, parents and the community about the content, purposes and consequences of standards · Alignment of standards, assessment and curricula, coupled with appropriate incentives for students and schools that meet the standards In the unlikely event that all of these efforts, including a change in school leadership, fail over a 3 - year period to «turn the school around,» drastic action is required.

David has over 30 years of experience successfully leading communications, marketing and change management efforts in various industries, including manufacturing, engineering, healthcare, education and state and federal government.