Ligation
of the common bile duct (BDL), modeling
cholestatic liver injury, resulted in a rapid onset
of bacterial overgrowth; however, it took 24 injections
of carbon tetrachloride (CCl4), modeling toxic liver injury, to observe bacterial overgrowth.
A unique difference in liver enzyme activity contrasting with other feline
cholestatic liver disorders is the relative inactivity
of γ - glutamyltransferase compared with alkaline phosphatase.