Sentences with phrase «of cholesterol synthesis»

So it could be argued that a high - carb diet is just as detrimental as a high - fat diet, in the context of cholesterol synthesis.

Although nutritional programming of cholesterol synthesis in later life is biologically plausible (13), there were several weaknesses in the data presented in our earlier review (10), which limited the strength of evidence for a causal association between breastfeeding and lower blood cholesterol concentrations in later life.

On a lithogenic diet, C57L / J mice develop gallstones as a result of abnormal regulation of cholesterol synthesis.

Isoprene is a known indicator of cholesterol synthesis and could offer valuable insights into a patient's metabolism.

They found decreased expression for almost all of the genes of cholesterol synthesis, including a gene called SREBP - 2, which acts as a master regulator for cholesterol production.

In 1964, Konrad Bloch received a Nobel Prize for his work elucidating the mechanisms of cholesterol synthesis.

In a recent minireview in The Journal of Biological Chemistry, Laura Sharpe and Andrew Brown of the University of New South Wales describe multiple ways various enzymes other than HMGCR are implicated in the modulation of cholesterol synthesis.

Could these inhibitors of cholesterol synthesis counter some lipid buildup in macrophages?

In their latest study, the Joslin researchers created a mouse model in which a gene known as SREBP2, the master regulator of cholesterol synthesis, has been knocked out.

They found that the majority of cholesterol synthesis - regulating genes in the hypothalami of these mice are down - regulated and that their expression normalizes if the mice are given insulin.

Statin Drugs lower cholesterol by inhibiting the enzyme HMG - CoA reductase, which is the rate - limiting enzyme of the mevalonate pathway of cholesterol synthesis.

Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic

On a lithogenic diet, C57L / J mice develop gallstones as a result of abnormal regulation of cholesterol synthesis (Xua et al. 2004).