Sentences with phrase «of cholinergic»

Neurologically speaking, it helps to raise your levels of cholinergic neurotransmitters that are responsible for being in a state of sexual arousal [6].

Ginsenosides increase acetylcholine levels in the brain by blocking the inhibition of the cholinergic pathway.

Juan Diego Pita - Almenar, Dinghui Yu, Hui - Chen Lu, Michael Beierlein (2014) «Mechanisms Underlying Desynchronization of Cholinergic - Evoked Thalamic Network Activity», Journal of Neuroscience 34 (43): 14463 - 14474.

In this study, the effect of lesion of the cholinergic pedunculo - pontine cell bodies (PPN) by the excitotoxin quisqualic acid was investigated on spontaneous locomotor activity and learning in rats.

The entorhinal cortex contains the highest level of cholinergic innervations [83] and in AD up to 80 % of cholinergic axons can be depleted [84].

C. Van Dort et al. «Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep.»

As a graduate student in James Townsel's lab, he studied the regulation and function of choline receptors, which are responsible for the transport of cholinergic neurons.

An emerging controller of the cholinergic effect of inflammation is micro-RNA-132 (5), whose involvement with post-stroke recovery awaits further studies and might open new venues for more rigorous assessment of the post-stroke risk of survival and systematic infection and the identification of conceptually novel targets for therapeutic interference.

«With this work, we are beginning to understand the role that changes in mitochondrial DNA play in the death of cholinergic neurons, which has been shown to be pivotal in the onset and progression of motor and non-motor Parkinson's disease symptoms.»

Not exact matches

The in - vivo (animal) study «Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress» was published in January of 2017.

All of the nerve agents, old and new, operate on the same biochemical principles and cause the same mechanism of injury by provoking a «cholinergic crisis».

Identifying changes in the mitochondrial DNA in PPN cholinergic neurons has the potential to allow the development of more effective treatments targeted to specific cell - types.

This study showed that mtDNA levels are higher in the surviving cholinergic neurons of the brainstem, but with both cell - types that undergo profound degeneration during Parkinson's disease.

The researchers report that mecamylamine reduces the release of dopamine by blocking binding sites on so - called nicotinic cholinergic synapses.

Together, these different yet interrelated approaches to estimate the cholinergic suppression of inflammation demonstrate its value for assessing the consequent risk of infection.

Osmotic release of β - glucuronidase from polymorphonuclear leukocyte lysosomes is inhibited by catecholamines and adenosine 3», 5» - monophosphate, and accelerated by cholinergic agents and guanosine 3», 5» - monophosphate.

The observation may be explained by impaired cholinergic neurotransmission that is also partly causative for the deterioration of memory in AD.

In the early 1980s these observations gave birth to «the cholinergic hypothesis» of memory loss.

An identified molluscan interneuron mediates different cholinergic synaptic actions by increasing the conductance of its follower cells to different ions.

Vinogradova OS, Brazhnik ES, Kitchigina VF, Stafekhina VS. Modulation of the reaction of hippocampal neurons to sensory stimuli by cholinergic substances.

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease.

The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD - 2 / liprin and UNC - 10 / RIM - dependent interactions.

Classical hallmarks of Alzheimer's disease (AD) are a synaptic loss, cholinergic neuron death, and abnormal protein deposition, particularly of toxic amyloid - β peptide (Aβ) that is derived from amyloid - β protein precursor (AβPP) by the action of beta - and gamma - secretases.

The typical forebrain cholinergic cell demise associated with AD brain results in a loss of presynaptic cholinergic markers and acetylcholine (ACh).

Abstract: Classical hallmarks of Alzheimer's disease (AD) are a synaptic loss, cholinergic neuron death, and abnormal protein deposition, particularly of toxic amyloid - β peptide (Aβ) that is derived from amyloid - β protein precursor (AβPP) by the action of beta - and gamma - secretases.

Sympathetic sprouting in visual cortex stimulated by cholinergic denervation rescues expression of two forms of long - term depression at layer 2/3 synapses.

Maturation of postsynaptic nicotinic structures on autonomic neurons requires innervation but not cholinergic transmission.

His lab is currently investigating the organization and function of a vastly underexplored but potentially highly important neural pathway from the cholinergic MT to DA neurons, and seeking potential causes, as well as molecular and cellular targets for treating schizophrenia.

NGF maintains and regulates the cholinergic phenotype of basal forebrain neurons [110, 111].

Therefore, the effect of J147 on the cholinergic system was investigated using the muscarinic receptor antagonist, scopolamine, which decreases central cholinergic neuronal activity.

Some of the projections from the medial septal area are cholinergic; the rest are GABAergic or glutamatergic.

They also show altered noradrenergic transmission in the hippocampus and cerebral cortex and degeneration of basal forebrain cholinergic neurons by 6 months of age.

Percentage of striatal cholinergic neuron morphological subtypes (unipolar, bipolar, or multipolar).

memory process; hippocampo - cortical interactions; cholinergic system; glutamatergic system; Cellular and molecular biology; hippocampal neurogenesis; animal models of Alzheimer's disease; animal models of schizophrenia

When co-administered with cholinergic precursors, they are able to increase the intrasynaptic levels of ACh more than when the single drugs given alone.

Experimental data and computational models suggest that blockade of muscarinic cholinergic receptors impairs paired - associate learning and increases proactive interference (E. DeRosa & M. E. Hasselmo, 2000; M. E. Hasselmo & J. M. Bower, 1993).

Cholinergic innervation of the frontal cortex: differences among humans, chimpanzees, and macaque monkeys.

Cholinergic neuron loss is a cardinal feature of Alzheimer's disease, a progressive brain disorder affecting memory, learning, attention and other cognitive processes.

A Cholinergic - Regulated Circuit Coordinates the Maintenance and Bi-Stable States of a Sensory - Motor Behavior during Caenorhabditis elegans Male Copulation

Our studies reveal the existence of two segregated excitatory synaptic microcircuits that propagate homeostatic sleep information from different populations of intrinsic MB «Kenyon cells» (KCs) to specific sleep - regulating MBONs: sleep - promoting KCs increase sleep by preferentially activating the cholinergic MBONs, while wake - promoting KCs decrease sleep by preferentially activating the glutamatergic MBONs.

YanGang Sun, Juan Pita - Almenar, Chia - Shan Wu, John J Renger, Victor N. Uebele, Hui - Chen Lu, Michael Beierlein (2013) «Biphasic cholinergic synaptic transmission controls action potential activity in thalamic reticular nucleus neurons», Journal of Neuroscience 33: 2048 - 59.

However, recent evidence indicates that apoE4 expression compromises the blood - brain barrier (as does apoE deficiency).40 Studies of brain histology, neurodegenerative markers, cholinergic activity, and neuronal function in knockout mice have been equivocal.39 Failure of detailed neurocognitive and retinal studies to demonstrate defects in our patient suggests either that the functions of apoE in the brain and eye are not critical or that they can be fulfilled by a surrogate protein.

Opt for cooling relief if you think you have «cholinergic urticaria,» a type of hives believed to be caused by sweating due to exercise, fever, or hot baths or showers, for example.

The combination of a dopaminergic pathway, insulin pathway, cholinergic (somatostatin suppression) and igf - 1 pathway create a powerful environment in the axis that stimulates a HGH pulse.

By inhibiting AChE, Horny Goat Weed supports higher levels of the key cholinergic neurotransmitters associated with sexual arousal.

The particular ability of Ashwagandha to help assist with mental acuity and reaction time (source), possibly due in part to cholinergic activity, also makes this herb of particular value to athletes.

The cholinergic system is an important part of the mechanism that regulates GH release stimulated by GHRH.

Improve cholinergic activities and the release of acetylcholine in the specific parts of the brain

Interactions ANTICHOLINERGIC DRUGS: Theoretically, concomitant use might decrease the effect of drugs with anticholinergic activity, due to the potential cholinergic activity of DMAE.

Hypocretin Neurons upregulate the production of molecules down several other pathways, too: these include noradrenergic, histaminergic, cholinergic, dopamine, and serotonergic.