Sentences with phrase «of choroidal»

She has also successfully litigated and settled cases relating to delayed ovarian cancer diagnosis, delayed diagnosis of choroidal melanoma, negligent urgent care treatment involving cellulitis and foot amputation, medical negligence in post-surgical care of prostate ablation and the management of wound care / decubitus ulcers.
The disease is reminiscent of the choroidal hypoplasia phenotype observed in humans in conjunction with craniofacial or renal abnormalities.
Grade 3 - Eye has twisted vessels in the retina and major areas of choroidal lesions with holes or pits in the eye
Grade 4 - Eye has twisted vessels in the retina, major areas of choroidal lesions, holes or pits in the eye, and retinal detachment

Not exact matches

Aura additionally announced today that the U.S. Food and Drug Administration (FDA) has granted AU - 011 fast track designation for the treatment of primary ocular melanoma, also known as uveal or choroidal melanoma.
Newborn with prenatally diagnosed choroidal fissure cyst and panhypopituitarism and review of the literature.
Because the new blood vessels (also known as choroidal neovascular membranes) can be so damaging, a wide variety of treatments have been tried to arrest their growth.
γ - Secretase Inhibition of Murine Choroidal Neovascularization Is Associated with Reduction of Superoxide and Proinflammatory Cytokines.
Intriguingly, these cells, which resemble perivascular macrophages or so - called «Mato Cells» in mammals, appear to emerge by transdifferentiation from endothelium of the optic choroidal vascular plexus, and as such would represent the first described perivascular cell population in the brain derived from vascular endothelium.
Choroidal neovascularization (CNV), the underlying process causing wet AMD and abnormal blood vessel growth, is the body's misguided way of attempting to create a new network of blood vessels to supply more nutrients and oxygen to the eye's retina.
Choroidal neovascularization is the out - of - control growth of fragile, leaky blood vessels that distort vision and damage the retina, which is seen in both diabetic retinopathy and the «wet» form of age - related macular degeneration (AMD).
Our objective is to determine whether this mutation is involved in AMD by (1) understanding the functional consequences of this genomic variation on expression of COL8A1 and / or its neighbor genes, and (2) investigating photoreceptors and RPE cell survival, retinal and choroidal angiogenesis, structure integrity of the choroid / Bruch's membrane, and the quality of the vision, in organisms with the COL8A1 mutation.
Specifically, the team hypothesizes that microRNA miR - 24 is a key regulator of actin cytoskeleton dynamics (i.e. the inner structural support of a cell); therefore, it plays a critical role in regulating multiple disease processes, including the angiogenesis (blood vessel growth), inflammation, and fibrosis (thickening and scarring of tissue) associated with choroidal neovascularization (CNV) in wet AMD.
If a dog has only choroidal hypoplasia sometimes the natural pigment in the back of the eye hides its presence.
The result is the percentage of collies affected with choroidal hypoplasia remains high, but the severe grades of the disease (colobomas and retinal detachments) have decreased due to this conscientious breeding.
The choroidal vessels may be reduced in number and of abnormal shape.
Border Collie breeders are usually very proactive in testing for the genetic diseases Collie Eye Anomaly / Choroidal Hypoplasia, Neuronal Ceroid Lipofuscinosis and Trapped Neutrophil Syndrome, but you should check with your breeder before buying a Border Collie on the status of their dogs for genetic diseases.
Collie Eye Anomaly (CEA)-- a complex of congenital defects including choroidal hypoplasia, also called chorioretinal dysplasia — a thinning of the vascular tissue within the eye), optic disc coloboma / staphloma — incomplete development of the optic nerve where it enters the eye, and retinal dysplasia or detachment — sections of retina, the vision reception tissue, that are not properly attached to the wall of the eye.
All dogs with CEA have bilateral choroidal hypoplasia (CH), also called chorioretinal dysplasia, a thinning of the vascular tissue in the back of the eye which does not significantly impair vision.
Ultimately he discovered that the recessive nature of the disease is due to a single gene of major effect that causes choroidal hypoplasia, the primary CEA defect.
Examples of the latter might include: choroidal hypoplasia in breeds not previously identified as having Collie Eye Anomaly, optic nerve colobomas, microphthalmia, multi-focal retinopathy in breeds not yet recognized as having CMR mutations, etc..
However, first of all, you have to examine pups very carefully from a very young age (starting by 5 - 6 weeks postnatal) to detect all the ones that «go normal», as some pups exhibiting unmistakeable choroidal hypoplasia by 6 weeks old, will have no ophthalmoscopically detectable lesions by 9 weeks old.
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