Sentences with phrase «of circadian disruption»

Also, the existence of circadian disruption during the treatment was linked to greater fatigue and body weight loss, two of the most worrying associated factors for doctors.

[26] Kohyama J. (2011) Neurochemical and Neuropharmacological Aspects of Circadian Disruptions: An Introduction to Asynchronization

Not exact matches

Disruption of the circadian clock in the host alters the rhythms and composition of the microbial community, leading to obesity and metabolic problems.

Disruption of these circadian rhythms may contribute to metabolic distress ailments, such as diabetes, obesity and high blood pressure.

Disruption of the circadian clock in humans is a hallmark of relatively recent lifestyle changes involving chronic shift work or frequent flights across time zones.

Others may investigate the neurobiology of hallucinations, disruptions in circadian rhythms, or precisely how drug addiction rewires the brain.

The disruption of a person's circadian rhythm — their 24 - hour biological clock — has been linked to an increased risk of breast cancer, according to new University of Georgia research.

Robb and He also advise that future research needs to examine social constraints — which may foster disruption of circadian rhythms — on shift workers.

«Minimising circadian disruption through the personalisation of chronotherapy delivery could help to improve clinical tolerability and potentially contribute towards the treatment being more effective,» concludes Ortiz.

If it does not function correctly, what is known as a circadian disruption or chronodisruption, has for years been linked to an increased incidence of cancer, obesity, diabetes, depression, cognitive problems or cardiovascular diseases.

«Also, circadian disruption in cancer patients aggravates the prognosis of the disease and the chance of survival for these patients diminishes,» Elisabet Ortiz Tudela, a researcher at the University of Murcia, said.

Most people have experienced the effects of circadian - rhythm disruption, after traveling across time zones or adjusting to a new schedule.

Furthermore, disruption of the body's natural sleeping and waking cycle (circadian desynchrony) often experienced by shift workers and others who work outside daylight hours, also appears to have a clear association with poor metabolic health, accompanied by increased rates of chronic illness and early mortality.

«We found that the majority of students were being jet - lagged by their class times, which correlated very strongly with decreased academic performance,» said study co-lead author Benjamin Smarr, a postdoctoral fellow who studies circadian rhythm disruptions in the lab of UC Berkeley psychology professor Lance Kriegsfeld.

«You've got to know what your quantities are,» says Mariana Figueiro, a professor at the Lighting Research Center at Rensselaer Polytechnic Institute in Troy, N.Y. Speaking in March at a conference on circadian disruption by the National Institute of Environmental Health Sciences, Figueiro called on the field to step up its game.

«The disruption of the circadian clock machinery seems to affect not only the rhythm of appetite regulation, but also the expression of the genes and proteins at their absolute level,» says Turek, whose team reports its findings online today in Science.

«Through the young eyes of a child, exposure to a bright blue screen in the hours before bedtime is the perfect storm for both sleep and circadian disruption,» LeBourgeois says.

Disruption of the circadian rhythm carries human health impacts, including an increased risk of breast cancer, metabolic diseases such as type - 2 diabetes and mood disorders, he said.

«To us, our results are consistent with what we already knew about these receptors, but they definitely show that chronic circadian disruption alone leads to malfunction of these receptors,» Fu adds.

«These results will drive development of personalised approaches to improve sleep - wake cycles of shift workers and other vulnerable people, and could potentially reduce the increased risk of disease due to circadian disruption.»

«We know that night time shift workers are more likely to suffer health problems due to disruption of their circadian clock, and the mismatch between the timing of the clock and their sleep - wake cycle.

Disruption of circadian clocks has been associated with accelerated aging and is a risk factor for many age - related diseases including cancer and diabetes.

Circadian rhythms are fundamental parts of our physiology, and their disruption can lead to numerous health problems — as well as the annoying jet - lag anyone who had taken a long flight will experience.

«This research shows that exposure to environmental toxins may be depressing the function of our circadian clock, the disruption of which is linked to increased rates of cancer, diabetes, obesity, heart disease, and depression,» said Jennifer Hurley, an assistant professor of biological sciences, a member of the Center for Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute, and senior author on this research.

Shift workers are at especially high risk for circadian rhythm disruptions, because of their non-traditional schedules.

And because circadian rhythms control the release and timing of hormones, mood disorders and sleep disruption may result.

Some researchers even promote the theory that the disruption of natural circadian rhythm from (blue) light after dark is a big contributing factor to the rise in obesity and chronic disease.

In addition to circadian rhythm disruption, elevated levels of psychological stress can also aggravate IBS.

A five - week study found that prolonged sleep restriction combined with circadian rhythm disruption significantly decreased participants» resting metabolic rate by an average of 8 % (18).

But when your body clock is disrupted or thrown out of balance by occasional or continuous interruptions of sleeping patterns, changes in light exposure, working the night shift regularly or other disruptions in your schedule, your natural circadian rhythms can become accelerated or slowed, leading to a cascade of physiologic impacts.

The researchers said finding a higher risk of diabetes even after adjusting for lifestyle factors and weight status suggests that additional factors, such as disruption of the circadian rhythm, may play a role.

A 2006 study from the University of Washington showed that disruptions in circadian rhythm can influence cancer progression and increase cancer risk.

The authors of the review suggested that cirrhosis can affect function in the area of the brain that regulates our circadian rhythm and this explains the sleep disruption associated with liver disease.

If circadian rhythm disruption is more sensitive to deficiency than night blindness, then it may occur in the absence of other clinical signs, at serum retinol concentrations within the reference range, and at vitamin A intakes above the RDA.

In just five nights, the iPad group displayed reduced levels of melatonin, they took longer to fall asleep, and they spent less time in the restorative REM sleep They also reported being sleepier and less alert in the morning, even after 8 hours of sleep, and showed disruption in their sleep - wake cycle, or circadian rhythm.

There is an accumulating body of evidence supporting meal timing to ensure proper circadian rhythm physiology, which is crucial given the prominent correlations between circadian disruption, disease pathology, and morbidity (Johnston, 2014).

Circadian misalignment and sleep disruption in shift work: Implications for fatigue and risk of weight gain and obesity

6) Straighten out cortisol — Not so much excess cortisol as disruptions of circadian rhythm.

Development of countermeasures and treatments for sleep and circadian disruption to improve public health and safety.

The specific cause of SAD is unknown, but factors that may contribute to SAD include disruptions in circadian rhythm and serotonin and melatonin levels as a result of seasonal changes in sunlight patterns.

Suppression of melatonin by light at night results in circadian disruption and has been implicated in sleep disturbances, increased risk for diabetes and obesity, as well as increased risk for more serious diseases, such as breast cancer, if circadian disruption occurs for many consecutive years, such as in night shift workers.

Suppression of melatonin by light at night results in circadian disruption and has been implicated in sleep disturbances, increased risk for diabetes and obesity, as well as increased risk for more serious diseases, such as breast cancer, if circadian disruption occurs for many consecutive years, such as in nightshift workers.

The suppression of melatonin by light at night reading that results in circadian disruption has been implicated in sleep disturbances, an increased risk for diabetes and obesity, as well as increased risk for more serious diseases, such as breast cancer, if circadian disruption occurs for many consecutive years, such as in nightshirt workers.)

Possibly, mania is a more purely biologically driven phenomenon than bipolar depression, with onsets more readily attributable to medication inconsistency, sleep deprivation, circadian disruption, or behavioral activation.21,22,84 - 86 In contrast, social and familial support has been found to protect against depression in bipolar and unipolar affective disorders, but the role of these variables in manic recurrences is unclear.86 - 88 An analysis of laboratory interactional data from a subset of 44 families in this sample revealed that treatment - related improvements in family communication skills were more closely associated with reductions in patients» depressive than manic symptoms.56 Thus, manic and depressive symptoms may be influenced by different constellations of risk and protective factors.

Based on the interpersonal psychotherapy model of depression and informed by the importance of regular social rhythms in bipolar disorder, 36 interpersonal and social rhythm therapy explores pathways to relapse, including disruptions to social and circadian patterns, non-adherence to medication, and stressful life events.37 The model suggests that positive and negative life events can adversely affect circadian rhythms, posing a risk of recurrence.36 It tackles these issues by establishing regular routines, exploring interpersonal conflict and addressing issues around social roles, 37 and it seems to have promise in managing bipolar disorder.