She is active in a number
of clinical and translational research projects, including the use of near - infrared fluorescent imaging in the surgical treatment of various diseases and application of minimally invasive tumor ablation in veterinary patients, and has authored numerous scientific publications and chapters in various veterinary textbooks.
Clinical Research Advocacy — Collaborating with other professional organizations to promote the advancement and support
of clinical and translational research to Congress and federal agencies
«This award is a testament to the quality
of clinical and translational research at Penn State,» said Dr. Lawrence Sinoway, CTSI director.
The Clinical and Translational Research Action subcommittee (CTRAC) identifies impediments to the conduct
of clinical and translational research, and provides recommendations to the URC regarding solutions and best practices.
We support a broad portfolio
of clinical and translational research through response mode funding, partnership initiatives and investments in clinical infrastructure.
Dr Peter Sneddon, Cancer Research UK's executive director
of clinical and translational research funding, said: «We are delighted that Professor Ashworth has won this well deserved award.
Firestein, who is also director
of the Clinical and Translational Research Institute at UC San Diego, said the work «opens up the potential for precision medicine approaches that allow us to target all of the joints, not just a subset.
«The unique aspect of this approach is the ability to improve symptoms and decrease joint damage while potentially avoiding any negative effects on normal immune responses and susceptibility to infections,» adds co-author Gary S. Firestein, M.D., dean and associate vice chancellor of Translational Medicine and director
of the Clinical and Translational Research Institute at UCSD.
«You shouldn't be testing everybody, but if there are reasons to believe that a test for H. pylori may come back positive, and it does come back positive, you should go on to treat,» says Dr. Traci Murakami, previous gastroenterology fellow at the UA and graduate
of the clinical and translational research graduate certificate at the Mel and Enid Zuckerman School of Public Health, now an assistant clinical professor of medicine at the University of Hawaii, Manoa, and lead author of the study.
The world
of clinical and translational research requires the support of individuals with varying expertise in diverse scientific and professional languages.
Not exact matches
CTI - 1601 was invented by R. Mark Payne, MD, professor
of Pediatric Cardiology at Indiana University School
of Medicine
and director
of the
Translational Research Training Program
of Indiana
Clinical Translational Sciences Institute.
A $ 291 million combined facility includes the Gates Vascular Institute
and University
of Buffalo's
Clinical and Translational Research Center.
More than 40 years after those early experiments, Jackson has risen to become the associate dean for
clinical research and director of Ohio State University (OSU) Medical Center's Center for Clinical and Translational Science
clinical research and director
of Ohio State University (OSU) Medical Center's Center for
Clinical and Translational Science
Clinical and Translational Science (CCTS).
«The most common time there is conflict
of interest is not with inventorship,» says Harry Greenberg, senior associate dean for
research at the Stanford University School of Medicine in Palo Alto, California, and director of the Stanford Center for Clinical and Translational Education and R
research at the Stanford University School
of Medicine in Palo Alto, California,
and director
of the Stanford Center for
Clinical and Translational Education
and ResearchResearch.
«In Portugal, we don't have a lot
of... companies that do
translational research, so the goal was really to apply our knowledge to the
clinical field
and to be able to establish a bridge,» Outeiro says.
That priority influences the design
of research questions, Weng notes,
and encourages scientists involved in basic
research, including postdocs, to participate in «very dynamic» collaborations with
translational and clinical groups.
The lead author
of the study was Jacqueline French, MD, professor
of neurology
and director
of Translational Research &
Clinical Trials Epilepsy at NYU Langone's Comprehensive Epilepsy Center.
With support from Ohio State's Center for
Clinical and Translational Science (CCTS), Dr. Bonny's
research team was able to comb through past
research to identify the top 30 nutrients that were most likely to influence the growth
of fat tissue in a low - estrogen environment.
D. degrees train individuals in
clinical and basic
research, but
translational research programs strive to integrate these two sides
of medical science by connecting people
and building networks.
In either case, the goal is becoming competent to interpret, evaluate,
and discuss different types
of research, rather than conducting it all yourself, says Doris Rubio, professor
of medicine, biostatistics, nursing,
and clinical and translational science at the University
of Pittsburgh.
Regardless
of the geographic setting, the goals
and challenges
of translational research are the same, says Liu: Getting funding
and infrastructure support from the government, training young investigators, creating a multidisciplinary community
of researchers who can effectively communicate with each other,
and finding ways to systematically implement
translational research results into
clinical practice.
In the United States, most training opportunities are through the
Clinical and Translational Science Awards (CTSAs), which were launched in 2006 based on the 2003 National Institutes
of Health (NIH) Roadmap for Medical
Research.
The National Institutes
of Health's (NIH's) Roadmap for Medical
Research acknowledges the importance of behavioral and social science research, and the agency's Clinical and Translational Science Awards require a behavioral science component in the programs of awardee insti
Research acknowledges the importance
of behavioral
and social science
research, and the agency's Clinical and Translational Science Awards require a behavioral science component in the programs of awardee insti
research,
and the agency's
Clinical and Translational Science Awards require a behavioral science component in the programs
of awardee institutions.
«Bioinformatics Instruction & Consultation, Collaboration, Evaluation» [PDF, 2.38 MB] Kristi L. Holmes, Ph.D., Becker Medical Library, Washington University in St. Louis «Community Engagement: Lost in Translation» [PDF, 2.1 MB] Layne Johnson, Ph.D.,
Clinical and Translational Science Institute, University
of Minnesota «Supporting
Clinical Research» [PDF, 785 KB] Jennifer A. Lyon, M.S., MLIS, Biomedical
and Health Information Services, University
of Florida «Library - based Support for
Translational Medicine» [PDF, 403 KB] Michele R. Tennant, Ph.D., MLIS, Biomedical
and Health Information Services, University
of Florida
Together with the European Renal cDNA Bank
and the Joint Institute for
Translational and Clinical Research (a collaboration between Peking University Health Sciences Center
and U-M), the U-M team found a simple, new test to identify one
of the nation's fastest growing chronic illnesses.
Other researchers include Randy Strong, Department
of Pharmacology
and Barshop Institute for Longevity
and Aging Studies, UTHSC, San Antonio, TX; Clifford Rosen, Center for
Clinical and Translational Research, Maine Medical Center
Research Institute, Scarborough, ME;
and Michael Nelson, Heart Institute, Cedars - Sinai Medical Center, Los Angeles, CA.
Back in the US,
and further along the
translational pipeline is Doug Lowy,
of the NIH in Bethesda, Maryland, who has already experienced the potential
of harnessing basic
research for
clinical use.
Beyond the rigorous
research education essential for all scientists,
translational scientists who will work at the boundaries
of discovery
and clinical science must possess an assortment
of practical
and logistical skills.
The study was supported by the Eunice Kennedy Shriver National Institute
of Child Health
and Human Development (K23 HD054720), Flora Family Foundation, UCSF Catalyst Award, UCSF Resource Allocation Program, Brain & Behavior
Research Foundation Young Investigator Award, Stanford University Lucile Packard Foundation for Children's Health, Spectrum Child Health &
Clinical and Translational Science Award
and the Extraordinary Brain Series
of the Dyslexia Foundation.
For Fuster, «This is a clear example
of the type
of the collaborative
and translational research favored by the CNIC, in which
research groups with different interests
and perspectives collaborate on
clinical problems that would not be easily resolved by teams working in isolation.»
This
research was also supported by the Clinical and Translational Research Institute of Southeast Wisconsin (NIH UL1RR
research was also supported by the
Clinical and Translational Research Institute of Southeast Wisconsin (NIH UL1RR
Research Institute
of Southeast Wisconsin (NIH UL1RR031973.)
«
Clinical and translational medicine represents an important arena
of investigation ripe for 21st - century science diplomacy, beginning with — although by no means limited to — infectious disease
research,» he
and co-author Vaughan Turekian, chief international officer
and director
of the AAAS Center for Science Diplomacy, write.
The SHOW project is supported by grants from the Wisconsin Partnership Program, the National Institutes
of Health (IRC2HL101468 - 01),
and the UW Institute for
Clinical and Translational Research (KL2 - RR025012).
The University
of Sheffield's Department
of Oncology
and Metabolism conducts world - class
research from basic
clinical and translational cancer
research to life course
research and basic level biology through to diseases such as diabetes
and osteoporosis.
«Activation
of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup
of proteins, such as alpha - synuclein, tau
and amyloid, common in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director
of Georgetown's Laboratory for Dementia
and Parkinsonism,
and scientific
and clinical research director
of the GUMC
Translational Neurotherapeutics Program.
«The exciting
research results being presented today underscore how transplants are becoming an increasingly successful treatment option for more patients with blood cancer than ever before,» said Jeffrey Miller, MD, moderator
of the press conference
and Deputy Director
of the Masonic Cancer Center
and the
Clinical and Translational Sciences Institute at the University
of Minnesota in Minneapolis.
His primary
clinical and research focus is dementia, with specific areas
of interest including biomarkers to assist in the diagnosis
and understanding
of disease mechanisms for Alzheimer's
and Parkinson's disease,
and translational research using novel therapeutic approaches.
Her
research is both
translational and clinical in nature
and centers on the human genetics
of healthy skin aging
and diseases related to aging skin, including new treatments for advanced basal cell skin cancers.
The life cycle
of a medical advance usually goes something like this: from discovery at the
research bench
and replication
of findings, to
translational research and clinical trials, to implementation.
Congress has questioned how NIH is managing its
Clinical and Translational Science Awards, which support
research such as this aging study at the University
of Kansas.
The
research was supported by the Michigan Institute for Clinical and Health Research and Michigan Center for Diabetes Translational Research, both of which receive NIH
research was supported by the Michigan Institute for
Clinical and Health
Research and Michigan Center for Diabetes Translational Research, both of which receive NIH
Research and Michigan Center for Diabetes
Translational Research, both of which receive NIH
Research, both
of which receive NIH funding.
William Crowley, director
of clinical research for Massachusetts General Hospital in Boston, observes that, although NIH's many programs to support training in
clinical and translational research have been «spectacular,» the academy is now filled with well - trained
translational researchers, all trying to land independent
research grants just as the NIH pay line is plummeting.
Between those two extremes
of basic
and applied knowledge lie two nascent, rapidly expanding subfields:
translational research informatics
and clinical research informatics.
«Beyond the rigorous
research education essential for all scientists, those
translational scientists who will work at the boundaries
of discovery
and clinical science must possess an assortment
of practical
and logistical skills,» the editorialists write.
All
of the authors share a deep interest in
clinical and translational research,
and the editorial expresses a collective commitment to the development
of an effective
clinical and translational research work force.
These ideas are summarized in a new paper, «Neuropsychiatric Signs
and Symptoms
of Alzheimer's Disease: New Treatment Paradigms,» published in the journal Alzheimer's & Dementia:
Translational Research &
Clinical Interventions.
Bringing together bench
and bedside is the purpose
of a new institute that aims to become a world - class «
translational» cancer
research centre, where the knowledge gained from basic
research is translated into
clinical applications.
The study was supported by grants from the National Institutes
of Health (R01 HL060056, P01 HL072058, K23 HL098743,
and R01 HL56810)
and by a Vanderbilt
Clinical and Translational Science Awards (UL1 RR024975) from the National Center for
Research Resources.
«Together with our partners, we are aiming at establishing a
research cluster in the Rhine - Main area that focuses on
translational and clinical research for the treatment
of non-alcoholic fatty liver disease,» emphasized Schattenberg
and Schuppan.
This advance in breast cancer
research reflects the mission
of Stem Cell Reports to provide an open - access forum that communicates basic discoveries in stem cell
research as well as
translational and clinical studies.