Sentences with phrase «of clinical investigation»

More importantly, specific results of clinical investigation provide empirical support.

Problem finding is an essential skill of clinical investigation, and the definition of a great problem sometimes occurs long after the solution has been observed.

The initial phase of clinical investigation is focusing on the safety of the cell replacement therapy combination products in patients.

A large number of clinical investigations have established its efficacy.

In a study published in European Journal of Clinical Investigation in 2000, researchers found that NAC significantly replenished stores of glutathione in patients with HIV.

Dr. Sharpless is an elected member of the American Society of Clinical Investigation and the Association of American Physicians.

The results were published in the Journal of Clinical Investigation in November.

A 2011 study in European Journal of Clinical Investigation found that probiotics can also help food to move through the digestive system more easily, leading to less frequent spitting up.

Last year, the Li lab published a paper in Journal of Clinical Investigation showing that CRISPR - Cas9 gene editing, delivered by viral vector, can reverse signs of HD in a mouse model.

In research reported online in the Journal of Clinical Investigation on February 14, Joslin clinical researchers, led by Dr. Allison Goldfine, took tiny samples of muscles from three categories of people: some who were healthy, some with a family history of diabetes who showed signs of insulin resistance although their blood glucose levels were normal, and some with full - blown type 2 diabetes.

In a second Journal of Clinical Investigation paper published this February, Nusrat and her colleagues show that intestinal cells release vesicles containing annexin A1 following injury.

A research team at the George Washington University (GW) published their results in the Journal of Clinical Investigation Insight.

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Shen - Ying Zhang, assistant professor of clinical investigation in the Casanova lab, evaluated seven children from unrelated families who had been exposed to a common virus (herpes simplex virus 1, influenza virus, or norovirus) and developed a life - threatening or lethal infection of the brain stem.

But on Monday, The Journal of Clinical Investigation published a study conducted by researchers at the Icahn School of Medicine at Mount Sinai, to see if Theranos» tests could be used to monitor the health of individuals.

This proof - of - principle study shows «for the first time... that human iPS cells can be used to model a diverse range of inherited diseases in adult cells,» the authors wrote in their paper, published online in The Journal of Clinical Investigation August 25.

In 2008, he took a job as a project leader at Institut Gustave Roussy's Centre of clinical investigation in biotherapy, managing a team focused on using host - related genetic factors to predict response to anticancer treatments.

The team will apply for CE marking, a symbol shown on devices demonstrating that they conform with relevant EU medical devices directives, so that the implant can be used across hospitals outside of the clinical investigation, across Europe and beyond.

In The Journal of Clinical Investigation researchers from VIB, KU Leuven (Belgium) together with colleagues from INSERM (France) now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

The Journal of Clinical Investigation vol.

From January 1991 to August 2001, Dr. Paya was Professor of Medicine, Immunology, and Pathology, and Vice Dean of the Clinical Investigation Program at the Mayo Clinic in Rochester, Minnesota.

The regulatory allowance of clinical investigation of the PEC - Direct product candidate in patients with type 1 diabetes in both Canada and the U.S. was also announced today.

Journal of Clinical Investigation doi: 10.1172 / JCI75429 (2014).

Although fatty liver disease usually does not progress to dangerous levels of liver inflammation, the condition is an increasing concern as its rates climb in the worldwide obesity epidemic, says Samir Softic, M.D., first author on a paper in the Journal of Clinical Investigation describing the research.

The Journal of Clinical Investigation noted that serotonin, which is a neurotransmitter that has a relaxing effect on the mind and body can help with GH production.

A 2011 study published in the Journal of Clinical Investigation determined that after feeding rodents a high - fat diet that consisted of 60 percent calories from fat, their hypothalamus suffered inflammation.

Finally, a study performed by University of Colorado scientists published in the January, 2006, issue of the Journal of Clinical Investigation indicates that soy foods could seriously harm patients afflicted with cardiomyopathy, a heart condition that affects 1 in 500 Americans and is the leading cause of death in young athletes.

Much of her clinical investigation has been focused on hematology, particularly platelet disorders, but she also has interest in minimally invasive procedures such as tracheal and urethral stenting.

The Research Institute Fund supports a wide range of clinical investigations undertaken by The AMC's research scientists who seek to define new diseases as well as develop diagnostic tests and advance therapies for naturally occurrirng diseases in animals.

Dr. Sugarman has been elected as a member of the American Society of Clinical Investigation, Association of American Physicians, and the Institute of Medicine.

As it turns out, exposure to lower temperatures increases brown fat activity — for example, one study published in the Journal of Clinical Investigation found that men who sat in a 63 - degree Fahrenheit room for two hours a day over the course of six weeks burned up to 289 calories more than those who sat in a room with normal indoor temperature!

But research published in this month's issue of the Journal of Clinical Investigation shows that newborn mice, instead of being immunized to the protein encoded by a DNA vaccine, actually learn to tolerate it.

These findings intrigued Joslin Principal Investigator Rohit N. Kulkarni, M.D., Ph.D., an expert in beta - cell biology and senior author on the paper published online in the Journal of Clinical Investigation on July 1.

Hawkins is co-first author on the Journal of Clinical Investigation paper, along with Philipp Kramer, formerly of UTHealth.

Reporting in the Journal of Clinical Investigation Insights, a team led by senior author Andrea Facciabene, PhD, a research assistant professor of Radiation Oncology and Obstetrics / Gynecology, found that the effectiveness of adoptive T cell therapy (ACT) in mice with cancer is significantly affected by differences in the natural makeup of gut bacteria and treatment with antibiotics.

A report in the 7 November issue of the Journal of Clinical Investigation suggests that a coating of complex sugars may help vicious strains of streptococcal bacteria cause life - threatening infections.

A study published in the Journal of Clinical Investigation in 1995 demonstrated that the normalization of plasma TSH and T4 levels with T4 - only preparations provide adequate tissue T3 levels to only a few tissues, including the pituitary (leading to a normal TSH level), but almost every other tissue will be deficient.

In the findings, published in the Journal of Clinical Investigation on December 11, researchers reveal that co-expression of cell surface receptor integrin αvβ3 and transcription factor Slug — a master regulator of a cell's ability to self - renew and differentiate — identifies rare stem - like cells in patient - derived tumor samples that are associated with metastasis.

In a letter to The Journal of Clinical Investigation, Theranos says the study is «flawed and inaccurate» and that it is «disappointed that any journal would accept this study for publication.»

(Theranos criticized the study as «flawed and inaccurate» in a letter to The Journal of Clinical Investigation, which published the research.)

The findings, publishing online this week in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections, which account for 14 million outpatient visits, nearly 500,000 hospital admissions and $ 3 billion to $ 4 billion in inpatient health care costs in the U.S. per year.

Their study, published Feb. 23 in the Journal of Clinical Investigation, identifies a small loop in the human prion protein that confers resistance to chronic wasting disease.

These cells homed in on the mouse livers, where they replaced dying mouse cells (The Journal of Clinical Investigation, DOI: 10.1172 / JCI40094).

A research team from Wayne State University recently published a paper in the Journal of Clinical Investigation that provides a paradigm shift in the understanding of cellular and molecular mechanisms underlying diabetic peripheral neuropathy (DPN) and wound healing in the treatment of corneal and skin diabetic ulcers.

The research, published today in the Journal of Clinical Investigation, describes the role of TNF receptor - associated factor 6 (TRAF6), an adaptor protein and E3 ubiquitin ligase, in ensuring the vitality of stem cells that regenerate muscle tissue.

Its altered form moves to the nucleus, where it increases the activity of a gene involved in metastasis (The Journal of Clinical Investigation, DOI: 10.1172 / JCI40433).