Sentences with phrase «of common human diseases»

The Swedish Genomes Program will focus on identifying genetic causes of common human diseases.

Examples of common human diseases caused by viruses include the common cold, the flu, chickenpox and cold sores.

Following the award presentation, Feinberg will deliver a lecture on the epigenetic basis of common human disease.

Not exact matches

Since the human genome was decoded in 2003, researchers have been developing a powerful method for comparing the genomes of patients and healthy people, with the hope of pinpointing the DNA changes responsible for common diseases.

Let us properly dwell upon it, being convinced that for the deadly disease of «busyness» there is no medicine so specific as the pondering of the hard path of the true sufferer and as a fellow human being sharing with him in the common lot of suffering.

There are eight human herpes viruses, and they cause a wide spectrum of diseases, ranging from common cold sores to cancer.

A joint work by EPFL, ETH Zürich and the CHUV has identified a pathological process that takes place in both mice and humans towards one of the most common diseases that people face in the industrialized world: type 2 diabetes.

In the United States, some of the most alarming outbreaks are occurring in the suburbs, where rising temperatures may help explain the spike in such tick - borne illnesses as babesiosis; hga (human granulocytic anaplasmosis), a potentially lethal flulike infection; and Lyme disease, the most common vector - borne disease in this country.

Adds Visscher: «This is entirely in line with theory and previous inference from SNP [variant] data, yet for some reason many researchers in human genetics and epidemiology continue to believe that there is a lot of non-additive genetic variation for common diseases and quantitative traits.»

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease (NAFLD) in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus.

Invasive aspergillosis (IA) is a serious disease of immune - compromised individuals and the most common invasive mold infection in humans.

Efforts include the National Institutes of Health Diabetes Genome Anatomy Project and another NIH - sponsored venture, the International HapMap Project, which is creating a map of regions in the human genome called haplotypes, where the underlying DNA influences common diseases like diabetes.

First, the researchers used mice that had been genetically modified to produce excess amounts of the human version of ß amyloid — a common Alzheimer's disease model.

Elegant, dainty, and deadly, it is the most common of all blood - sucking arthropods and the most important insect carrier of human disease, transmitting not only malaria but also yellow fever, dengue, West Nile virus, encephalitis, and the tiny worms that cause elephantiasis.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

Underlying the most common human diseases, however, are entire networks of genes.

A team at the University of Oxford assessed 199 such programmes and found potential welfare issues in two - thirds of them, the most common being mortality, disease and conflict with humans.

Researchers at University of California, San Diego School of Medicine have induced this all - too - common human experience — or a close version of it — permanently in rats and from what is observed perhaps derive clues about why strokes and Alzheimer's disease can destroy a person's sense of direction.

The «old friends hypothesis» proposes that the human immune system can not learn to regulate itself without exposure to common pathogens like helminths that have coevolved with people and that modern hygienic practices deprive people of this necessary exposure, possibly explaining the relatively higher and more recent prevalence of immune diseases in industrialized countries like the U.S. Loke plans to continue researching helminthic therapy in people and in monkeys.

Fecal contamination in water is one of the most common reasons for human diseases.

The PHPN uses information in human disease networks in conjunction with network science tools to show clusters of related disorders sharing common genetic backgrounds.

Enter a mutant mouse strain that is afflicted at a young age with many of the diseases common to older humans.

A year later, Carlo Croce, now director of the Human Cancer Genetics Program at Ohio State University, reported that chronic lymphocytic leukemia (CLL), the most common form of the disease, was caused by deletion of two microRNA genes.

But INB found a way to trick spinach (along with Swiss chard and petunias) into producing harmless bits and pieces of common human pathogens that cause diseases like flu and plague (inset).

Professor Yoshihito Watanabe (WPI - ITbM, Cooperating Researcher), Associate Professor Osami Shoji, Ms. Chikako Shirataki of Nagoya University and co-workers have found a new method using an artificial metalloprotein (a protein that contains a metal) to inhibit the growth of Pseudomonas aeruginosa bacteria, which is a common bacterium that can cause diseases in humans and evolves to exhibit multiple antibiotic resistance.

«It is now clear that common risk variants fail to explain the vast majority of genetic heritability for any human disease,» they wrote in an essay, arguing that many of the hundreds of GWAS findings to date «stem from factors other than a true association with disease risk.»

«Lab - grown human colons change study of GI disease: Stem cell derived organoids fill gap in modeling common ailments.»

On the negative side, the researchers found that many of the genes whose activity is unique to modern humans are linked to diseases like Alzheimer's disease, autism and schizophrenia, suggesting that these recent changes in our brain may underlie some of the psychiatric disorders that are so common in humans today.

The pigs showed both movement problems and respiratory difficulties common to human patients, and it is hoped that this model will assist in the creation of new treatments for Huntington's — a genetically inherited and fatal disease which affects tens of thousands of people.

About deCODE deCODE is a biopharmaceutical company applying its discoveries in human genetics to the development of diagnostics and drugs for common diseases.

Telomeres have recently emerged as a read - out of human cellular aging and their shortening actually contributes, along with other factors, to various common age - associated diseases.

for example, no HD mouse model shows signs of «chorea», the dance - like movements that are a common feature of the human disease.

The condition is more common than muscular dystrophy and cystic fibrosis, but the development of new therapeutic concepts is hindered by the fact that unlike muscular dystrophy and cystic fibrosis, where a single mutated gene causing the disease is known, the entire human chromosome 21 (containing around 300 genes) still has to be dissected into individual gene - dose contributions to the DS symptoms.

Human genetic studies strongly point to apolipoprotein E (APOE) and microglia (the immune cells of the brain) as, respectively, the most important gene and cell type in the chain of events leading to Alzheimer's disease (AD), a common disorder in the elderly in which the brain is damaged and memories falter.

Our wet - lab research is focused on the study of Brucella, a facultative intracellular bacterium that causes brucellosis, one of the most common zoonotic diseases in the world in humans and a variety of animal species.

Investigators in the CRGGH will develop genetic epidemiology models that will explore the patterns and determinants of common complex diseases in populations in the United States and other human populations around the world.

His lab develops isogenic human pluripotent stem cells and transgenic animals to model disease, with the goal of delineating novel approaches to influence outcomes for Huntington disease (HD) and Fragile X Syndrome (FXS), the most common genetic causes of dementia and intellectual disability, respectively.

The quality and scale of deCODE's in - house, CLIA - registered genotyping laboratory underpins deCODE's global leadership in the discovery of variations in the sequence of the human genome conferring risk of common diseases.

This study of human genetic variation and its relationship to health and disease involves a large number of study participants and will capture not only common single nucleotide variations but also rare copy number and structural variants that are increasingly thought to play an important role in complex disease.

In human disease, a mutation from G to A is extremely common; these alterations have been implicated in, for example, cases of focal epilepsy, Duchenne muscular dystrophy, and Parkinson's disease.

The idea behind a â $ œHuman Vaccine Projectâ $ is to combine efforts at developing vaccines for major (but very different) diseases such as influenza, dengue, HIV, hepatitis C, tuberculosis and malaria, with the rationale that what scientists working on those diseases have in common is the Ray Ban outlet challenge of working with the human immune system.

deCODE is a biopharmaceutical company applying its discoveries in human genetics to the development of drugs and diagnostics for common diseases.

«Although we first became aware of prions because they cause several bizarre neurological diseases, the discovery that something so awesomely similar happens in organisms as different as humans and yeast makes us suspect that there is a fundamental, common biochemical process at work here,» said study director Susan Lindquist, PhD, professor of molecular genetics and cell biology and an investigator in the Howard Hughes Medical Institute at the University of Chicago.

Not so long ago, there was a hope in the research community that common genetic variation, i.e. variants present at minor allele frequencies > 5 % in human populations, might explain most or all of the heritability of common complex disease.

About deCODE genetics deCODE is a biopharmaceutical company applying its discoveries in human genetics to the development of drugs for common diseases.

In humans, PKD is one of the most common diseases caused by a mutation in a single gene.

Potential projects include identifying common pathways that modify retinal degenerative disease from a large collection of actively maintained mouse models; determining molecular networks implicated in pathological disruption of the retinal pigment epithelium; identifying molecular pathways that regulate postnatal ocular growth; and using mouse models to assess the pathogenic role of gene variants that increase the risk of age - related macular degeneration as identified by human genome - wide association studies.

Performing genetic studies in multiple human populations can identify disease risk alleles that are common in one population but rare in others, with the potential to illuminate pathophysiology, health disparities, and the population genetic origins of disease alleles.

Human Genetic Variation and Common Disease David Altshuler, MD, PhD Professor of Genetics and of Medicine, Harvard Medical School and Massachusetts General Hospital Deputy Director and Chief Academic Officer, The Broad Institute of MIT and Harvard

About deCODE deCODE is a biopharmaceutical company applying its discoveries in human genetics to the development of drugs and diagnostics for common diseases.