The research is in the very early stages, but the researchers have so far shown promising results in a
proof of concept study in mice.
The proof
of concept study represents a promising route to mitigate the buildup of carbon dioxide, a major greenhouse gas in the environment, said researchers.
Our proof
of concept study suggests this network biology approach could help us identify new medications for epilepsy, and the methods can also be applied to other diseases.»
The proof
of concept study used a beta version of Watson for Genomics technology to help interpret whole genome sequencing (WGS) data for one patient.
Results from an imaging study in healthy volunteers subjected to capsaicin injection and analgesics give sample size estimates for imaging endpoints useful in small proof
of concept studies for drug development.
Porsche's entry into Formula E in 2019 will coincide with the market launch of the production
version of the concept study Mission E. Porsche will invest more than $ 6 billion in electric mobility before the end of 2022.
University students in the UK are required to write essays, dissertations, book reports, research proposals, case study, and coursework to demonstrate their knowledge,
understanding of the concepts studied and ability to apply them.
Researchers performed the proof
of concept study in vitro using chemotherapy drugs and cancer cells.
«Nonetheless, the proof
of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.
Study co-author Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs for the Mount Sinai Health System, and a world expert on the neurobiology and treatment of mood disorders, said: «What we have here is a proof
of concept study and we consider the results very promising.
The proof
of concept study is aimed at determining how different individuals will respond to a drug treatment and could help assess whether a drug is suitable for a particular patient based on measurements taken from the patient's blood.
For this proof
of concept study, the scientists analyzed rodent cells» electrical activity for up to 30 days, reporting that the cells displayed characteristics and changes mimicking physiological responses described in literature.
«This is a very important proof
of concept study,» said senior author Yadong Huang, MD, PhD, an associate investigator at Gladstone Institutes and associate professor of neurology and pathology at UCSF.
Indrani Sarkar (Buchholz, MPG)-- «Directed evolution of an HIV - 1 LTR specific recombinase for anti-retroviral therapy - a proof
of concept study» (2006)
In this proof
of concept study, Dr Stephen Jolles and colleagues from the University Hospital of Wales used an imaging technique called FDG PET - CT to simultaneously assess anatomical structure and metabolic activity in a patient with GLILD.
A new proof
of concept study has shown that an imaging technique more commonly used to assess cancer patients may also be of help in assessing disease and treatment effects in patients with inflammatory diseases.
In the proof
of concept study, 12 patients received nilotinib, an FDA - approved drug for leukemia.
Parra said she decided to allow Damian's eye and eye fluid to be used in Berry's proof -
of concept study (he was one of three patients involved) because she hates to think of other parents going through what she did.
The investment will be made in sixteen proof
of concept studies, which will last... Read more →
(ref) After their initial proof
of concept studies, they teamed up with Amgen, a company with deeper pockets and broad experience in the pharmaceutical industry.
Effects of schema group therapy in elderly outpatients: a proof
of concept study.