1) Published paper as the first author in Journal
of craniofacial surgery 2008, «Hemimaxillofacial Dysplasia (HMD)-- A variable presentation» 2) Presentation on research day, UCSF, CA on» Rigid external distractor for mandibular distraction in Dysgnathia Complex» (2007) 3) AAOMS data collection study about Orthognathic Surgery outcomes (2006 — 2007).
Reconstruction
of craniofacial defects with bone - marrow - coated Polycaprolactone scaffolds.
The work is «solid» and «perhaps the most sophisticated analysis
of craniofacial traits undertaken to date,» says Theodore Schurr, a molecular anthropologist at the University of Pennsylvania.
As a graduate student, Teran worked with plastic surgeon Court Cutting at New York University Medical Center using computer graphic methods to develop statistical descriptions of three - dimensional images
of craniofacial malformations and propose surgical methods for their correction.
Such basic knowledge about the development of teeth or bones adds to understanding
of craniofacial abnormalities, which are among the most common birth defects in humans.
Not exact matches
Shepard, 19 noted that the largest increments in
craniofacial growth occurred within the first 4 years
of life, and that
craniofacial development is 90 % completed by 12 years
of age.
Referrals to
craniofacial centers for evaluation
of deformational plagiocephaly and brachycephaly are increasing.8 This increase in deformations has been temporally linked to the Back to Sleep program advanced by the American Academy
of Pediatrics in 1992 that advises the avoidance
of the prone sleeping position as a method
of reducing the rates
of sudden infant death syndrome.10,, 12,13 There is a delay in early gross motor milestones in children forced to sleep supine but these delays seem transient and have not been linked as yet to any longer term problems.14 Children who are encouraged to sleep on their backs and develop abnormal head shapes as a result are a different population than children who spontaneously restricted their movement in bed for one reason or another.
In ∼ 10 %
of affected infants with plagiocephaly, there will be a permanent deformity with a mild to severe cosmetic effect.5 Patients with moderate to severe asymmetry are often referred to a
craniofacial center for consideration
of treatment.
Dr. Patel, an assistant professor at Loyola University Chicago Stritch School
of Medicine, is a plastic and reconstruction surgeon who specializes in
craniofacial surgery and cleft conditions at Loyola University Health System.
«The results are important because diabetics have a significantly higher fracture risk and their healing process is always delayed,» said Xin Li, PhD, associate professor
of basic science and
craniofacial biology at NYU Dentistry, and the study's senior investigator.
The scientists heated chicken embryos to 40 ° to 41 ° Celsius for an hour and compared them with embryos incubated at a standard laboratory temperature
of 37 ° C. Those chicks exposed to a high «fever» developed
craniofacial defects, such as a shorter upper beak, and cardiovascular defects.
It can severely harm a fetus, causing
craniofacial, cardiac and central nervous system defects, as well as a high likelihood
of miscarriage or medical termination.
«Fascinating genetic studies had been done on SMCHD1 that linked the gene to FSHD2, a rare muscular dystrophy involving the interaction
of multiple genetic sites, but it had never been connected to
craniofacial abnormalities,» says Michael Talkowski, PhD,
of the MGH Center for Human Genetic Research, co-senior author
of the Nature Genetics paper.
«Among families having several members with SMCHD1 mutations, we observed some who did not have complete arhinia but had an abnormally small nose or lacked a sense
of smell, as well as the one individual that had symptoms
of FSHD2 but no
craniofacial abnormalities, indicating this is not a simple genetic model,» says Talkowski.
Microdeletions
of chromosome 22q11 are the most common genetic defects associated with cardiac and
craniofacial anomalies in humans.
Their embryos had more profound defects than were seen in the Esrp1 - null mice, including
craniofacial and forelimb defects, and the complete absence
of lungs and salivary glands — two organs made up largely
of epithelial cells.
This study, titled «Enamel Hypomineralization and Structural Defects in Amelotin - deficient Mice,» is published in the OnlineFirst portion
of the Journal
of Dental Research: the journal for dental, oral and
craniofacial research.
Other uses have been limited to simulating specific body parts, such as an organ, a cluster
of muscles or a
craniofacial malformation.
It's warm and dark, food goes in there several times a day, and there are lots
of little nooks and crannies where food can get caught,» says dentist and oral microbiologist Donna Mager
of the Forsyth Institute, a nonprofit group that focuses on oral and
craniofacial research.
Longaker, a biologist and pediatric
craniofacial surgeon at Stanford University Medical Center, figured these multipotent cells — a kind
of stem cell — might be useful for treating bone fractures and defects.
Other speakers proposed that all
of these traits, from hormone levels to
craniofacial features, have a common root in early embryonic development.
These powerful techniques — originally developed in the automotive and aerospace industries — are already being used to help surgeons solve complex problems in
craniofacial reconstruction through analysis, planning, virtual surgery, 3D printing, and evaluation
of surgical results.
«In some way, it seems trivial, but a reason why chins are so interesting is we're the only ones who have them,» says Nathan Holton, who studies
craniofacial features and mechanics at the University
of Iowa.
While used mainly in
craniofacial reconstruction so far, 3D planning and CAD / CAM techniques have the potential for advances in practically every area
of plastic and reconstructive surgery, according to the review by Drs. Miles J. Pfaff and Derek Steinbacher
of Yale University.
What is exciting is that many
of these associations involve chromosomal regions harboring genes with known
craniofacial function.
This study is published in the OnlineFirst portion
of the Journal
of Dental Research: the journal for dental, oral and
craniofacial research and a companion podcast is also available for download.
In addition, we participate in multi-specialty clinics for
craniofacial anomalies, Down syndrome, neurogenetics and genetic disorders
of the skin.
We hope to apply our findings to the understanding
of human diseases and
craniofacial evolution.
We have identified two families with a previously undescribed lethal X-linked disorder
of infancy; the disorder comprises a distinct combination
of an aged appearance,
craniofacial anomalies, hypotonia, global developmental delays, cryptorchidism, and cardiac arrhythmias.
In the recent case series, most infants with probable congenital ZIKV infection were noted to have
craniofacial disproportion (95.8 %) and, to a lesser degree, biparietal depression (83.3 %), prominent occiput (75 %), and excess nuchal skin (47.9 %).38 Features supportive
of the FBDS phenotype scattered through published reports include redundant scalp, 27,36,39,41 occipital prominence and / or overlapping sutures,14,20,22 - 24, 26,27,38 and typical
craniofacial appearance with disproportion.13, 27,33,34,40 The FBDS phenotype is also prevalent in ZIKV - related media.47 Among infants with severe microcephaly, the pattern appears to be consistent, although the degree
of cranial vault deformation varies.
National Institute
of Dental and
Craniofacial Research (NIDCR)-- Est. 1948 NIDCR provides leadership for a national research program designed to understand, treat, and ultimately prevent the infectious and inherited
craniofacial - oral - dental diseases and disorders that compromise millions
of human lives.
The
craniofacial index (facial area versus cranial area)
of all «habilines», including 1470 falls within the australopithecine range and outside the human range including erectus.67, 68
I am also studying a mouse model that exhibits sex reversal,
craniofacial defects and shortening
of the limbs characteristic
of some forms
of human dwarfism.
While The American Journal
of Clinical Nutrition reports «
craniofacial... malformations» (those affecting the head and face) occurring in animals exposed to high Vitamin A intake during embryonic development
The disease is reminiscent
of the choroidal hypoplasia phenotype observed in humans in conjunction with
craniofacial or renal abnormalities.
If part
of a person's body has become disfigured, such as a woman's breast due to cancer, or a man whose face has been burned in a fire, or there are birth defects such as a cleft lip and palate or
craniofacial defects, a qualified plastic surgeon would be the one to correct these conditions.
Oral health includes the prevention and treatment
of oral, dental and
craniofacial disorders and diseases.