Sentences with phrase «of cyclooxygenase»

There are two types of cyclooxygenase: COX - 1 and COX - 2 inhibitors.

There are two main forms of cyclooxygenase: COX - 1 (which makes «good» prostaglandins) and COX - 2 (which makes the bad ones).

It turns out that there are several types of cyclooxygenase, however.

Ibuprofen is what is called a non-selective cyclooxygenase inhibitor, which means it inhibits all types of cyclooxygenase, not just the ones that produce inflammatory mediators.

Previcox (firocoxib) is a type of analgesic that acts by inhibiting the action of cyclooxygenase 2 which leads to the reduction in the formation or synthesis of prostaglandins and similar proinflammatory substances from arachidonic acid.

In the case of cyclooxygenase (COX), it stimulates cells to produce several substances, including prostaglandins, after the cells are damaged.

Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase - 2 mediated through Toll - like receptors 4

In addition, LA promoted inflammatory processes activating the nuclear factor - κB transcription factor as well as stimulating the expression of cyclooxygenase - 2 and pro-inflammatory cytokines.

Additionally, two inflammation markers were determined, namely, the expression levels of cyclooxygenase 2 and the levels of secreted monocyte chemoattractant protein - 1.

Direct Transcriptional Up - regulation of Cyclooxygenase - 2 by Hypoxia - Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF - 1 Transcriptional Activity during Hypoxia

Role of Cyclooxygenase and Derived Reactive Oxygen Species in ϱ - Kinase - Mediated Impairment of Endothelium - Dependent Vasodilation and Blood Flow after Ischemia - Reperfusion of the Rat Kidney.

Heterotrimeric G - proteins activate Cl - channels through stimulation of a cyclooxygenase - dependent pathway in a model liver cell line.

Aspirin and its cousins work by blocking production of cyclooxygenase (COX) enzymes.

Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) relieve pain and inflammation by blocking either or both of the cyclooxygenase (COX) enzymes, which produce pro-inflammatory prostaglandins.

Curcumin can inhibit both the activity and the synthesis of cyclooxygenase - 2 (COX2) and 5 - lipoxygenase (5 - LOX), as well as other enzymes that have been implicated in inflammation.

Not exact matches

In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.

He and Gong are interested in the function of an enzyme in the brain called cyclooxygenase - 2 (COX - 2).

Now a group has discovered an enzyme that fits the profile of the long - sought site of action for the drug: a new variant of the well - studied cyclooxygenase (COX) enzymes.

One pathway of arachidonic acid oxygenation leads to the formation of prostaglandins and related molecules; the initial step in their formation is catalyzed by one of the two cyclooxygenase enzymes, which are inhibited by aspirin and the nonsteroidal anti-inflammatory drugs.

Induction of a CD4 + T regulatory type 1 response by cyclooxygenase -2-overexpressing glioma.

One of these enzymes, cyclooxygenase - 2 (COX - 2), is an inducible enzyme, the biosynthesis of which is stimulated by growth factors, cytokines, and endotoxin, and is inhibited by glucocorticoids.

Cyclooxygenase (COX, also referred to prostaglandin G / H synthase) is often the rate - limiting enzyme for the production of prostaglandins and thromboxanes from free arachidonic acid.

Cyclooxygenase -2-dependent expression of angiogenic CXC chemokines ENA - 78 / CXC Ligand (CXCL) 5 and interleukin - 8 / CXCL8 in human non-small cell lung cancer.

Role of p300 and PCAF in regulating cyclooxygenase - 2 promoter activation by inflammatory mediators.

Cyclooxygenase 2 - dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer.

At the same university, a follow - up study found that pine bark extract also inhibits COX - 1 and COX - 2 (forms of the enzyme cyclooxygenase) 4.

Their antioxidant and anti-inflammatory activities are largely due to their abilities to scavenge the reactive oxygen species (ROS) and improvement of antioxidant status by attenuating the activity of NF - κB and suppressing the expression of several inflammatory cytokines and chemokines including monocyte chemotactic protein - 1 (MCP - 1), nitric oxide synthase, cyclooxygenases, lipoxygenases, cellular adhesion molecules, tumor necrosis factor and interleukins.

These acids decrease the body's production of a long list of pro-inflammatory biochemicals, including the same ones targeted by most NSAIDs — cyclooxygenase (COX 1 and 2).

Evans JF: Rofecoxib (Vioxx), a Specific Cyclooxygenase - 2 Inhibitor, Is Chemopreventive in a Mouse Model of Colon Cancer.

Cyclooxygenase produces of a number of different compounds known as prostanoids (prostaglandins, prostacyclin and thromboxanes).

It is mainly contained in the seeds and has been shown to inhibit cyclooxygenase - 2, an inflammatory protein related to a number of health conditions, including Benign Prostatic Hyperplasia (BPH).

The eugenol component of basil's volatile oils has been the subject of extensive study, since this substance can block the activity of an enzyme in the body called cyclooxygenase (COX).

As mentioned previously, ginger properties include anti-inflammatory actions that stem from a group of compounds called gingerols, which work by inhibiting the prostaglandin - biosynthesizing enzyme, known as PH synthetase or cyclooxygenase (COX).

Without cyclooxygenase, the swelling, discomfort and high temperature of inflammation do not take place.

(8) In another study, the anti-inflammatory properties of the active ingredient in schisandra, schisandrin, were shown to result from the inhibition of nitric oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible nitric oxide synthase (iNOS) expression.

Anti-Inflammatory Effects: Eugenol (one of basil's volatile oils) can also help block the enzyme cyclooxygenase (COX) in the body.

Laboratory findings at Michigan State University suggest that ingesting the equivalent of 20 tart cherries inhibits enzymes called cyclooxygenase - 1 and -2, which are the targets of anti-inflammatory drugs.

'' [NSAIDs] are strong inhibitors of the enzyme cyclooxygenase — COX — which is an important enzyme that is responsible for producing inflammatory mediators,» Etminan says.

Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase (COX), an enzyme involved in the production of prostaglandins, some of which are mediators of the inflammatory response.

Although NSAIDs are a diverse group of drugs, they all work by blocking cyclooxygenase.

Deracoxib is an NSAID that acts specifically on the cyclooxygenase - 2 enzyme which has been shown to be the principal mediator of inflammatory processes.

Second, cyclooxygenase (COX) is also responsible for maintaining the health of many tissues in the dog's body; for example, the lining of the stomach.