Sentences with phrase «of cystic fibrosis patients»

Bacteria can stick together to form slimy sheets called biofilms that yellow people's teeth, line the lungs of cystic fibrosis patients and often resist antibiotics.

Gerald Schwank et al. «Functional Repair of CFTR by CRISPR / Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients.»

It's not hard to see a scenario where the pharma lobby enlists an outraged parent of a cystic fibrosis patient to decry government overreach that restricts patient choice.

He examined Pseudomonas aeruginosa, a microbe that inhabits the mucus clogging the airways of cystic fibrosis patients.

Although scientists first mapped the genetic structure of P. aeruginosa 15 years ago, efforts to pinpoint how it behaves during an infection and which genes would need to be turned off to stop its spread have been hampered in part by the difficulty of mimicking the unique conditions of a cystic fibrosis patient's lungs.

Although Kalydeco has so far been approved only for 4 per cent of cystic fibrosis patients, who carry a specific mutation, the three drugs together could treat more than 90 per cent of people with the disease.

He benefits from a medication that targets the underlying cause of the disease for a small subset of cystic fibrosis patients.»

About 80 percent of cystic fibrosis patients have at least one antibiotic - resistant infection in their lungs by age 18.

While PUR1900 has the potential to improve the lives of cystic fibrosis patients, especially children and young adults, it also could bring significant revenues for Pulmatrix.

(NewsUSA)- Up to half of all cystic fibrosis patients have fungal infections in their lungs caused by a spore - forming mold named Aspergillus fumigatus.

A 2006 study did find that inhaling salt - infused vapors improved the breathing of cystic fibrosis patients, but as far as recreational use of halotherapy, the evidence is slim.)

That raises the possibility of using them to treat infections caused by biofilms, such as the Pseudomonas aeruginosa infections that often affect the lungs of cystic fibrosis patients.

42) Schwank, G., Koo, B.K., Sasselli, V., Dekkers, J.F., Heo, I., Demircan, T., Sasaki, N., Boymans, S., Cuppen, E., van der Ent, C.K., Nieuwenhuis, E.E., Beekman, J.M. and Clevers, H. Functional repair of CFTR by CRISPR / Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

Staphylococcus aureus and Pseudomonas aeruginosa commonly co-infect wounds, catheters and lungs of cystic fibrosis patients.

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research.

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research published in PLOS Pathogens.

These findings suggest a potential mechanism by which S. parasanguinis, which is normally found on the surface of teeth, might colonize the lungs of a cystic fibrosis patient and inhibit P. aeruginosa.

To make these cracks, the researchers turned to Pseudomonas aeruginosa — a bacterial species that often builds biofilms within the lungs of cystic fibrosis patients, which can lead to chronic obstructive pulmonary disease and subsequently death.

How do microbes duke it out in the lungs of cystic fibrosis patients?

The first of many probable applications will likely be the chronic bacterial infections in the lungs of cystic fibrosis patients «that frequently develop resistance to all standard antibiotics, and are the leading cause of death in these patients,» says senior author Ronald Montelaro.

In the past, researchers studied Pseudomonas in isolation despite the fact that it's rarely the lone bacterium in the lungs of people with CF. Hoffman decided to study how Pseudomonas and Staphylococcus aureus — the other bacterium most commonly found in the lungs of cystic fibrosis patients — behave when the two are grown together.

We also sequenced several members of the Burkholderia cenocepacia complex that are important pathogens in the lungs of cystic fibrosis patients.