Although none of these organisms has yet been isolated, observed under the microscope nor cultured, these genome sequences provide us with an unprecedented opportunity to explore the origins
of these cytoskeletal elements and promise to shed light on the evolutionary transition that led to the emergence of eukaryotes.
Not exact matches
Actin is a filamentous protein, which together with other
cytoskeletal elements forms a dynamic network
of filaments that provide both structural support, as well as critical functional capabilities, to the cell.
Proper transfer
of V1 complexes or subunits from the membrane to the cytoplasm and back appears to require not only phosphorylation events, conformational changes in the V1VO holoenzyme, the V1 complex and the V1 subunit C, but also the temporary interaction with protein kinase A,
cytoskeletal elements, the heterotrimeric protein complex RAVE and the glycolytic enzyme aldolase.
Asymmetric RNA localisation can be achieved by different mechanisms, such as active transport
of RNAs by motor proteins moving on
cytoskeletal elements, local protection
of RNAs from degradation, facilitated diffusion and trapping.
Many
of the downregulated genes are smooth muscle
cytoskeletal elements, including TCAP (titin - cap), TPN1 (tropomyosin), DMD (dystrophin), SMTN (smoothelin), TAGLN (transgelin), MYH11 (smooth muscle myosin heavy chain 11), and CNN1 (smooth muscle calponin 1).