Sentences with phrase «of cytotoxic agents»

Mueller H, Kassack MU, Wiese M. Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.

The targeted drug delivery appears to be a very promising strategy for controlling the biodistribution of the cytotoxic agent only on malignant tissues by linking it to tumor - targeting moiety.

Not exact matches

No targeted therapy has been approved for noninflammatory and inflammatory triple - negative breast cancer tumors, and the standard of therapy for these tumors is a combination of conventional cytotoxic chemotherapeutic agents.

«These new results are significant because they represent the discovery of a number of more potent variations of the natural product as cytotoxic agents against cancer cells,» Nicolaou said.

These agents will possibly increase the cytotoxic action of MDR - related drugs by preventing the extrusion of anticancer drugs from the target cells.

Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor.

Immunologic checkpoint blockade with anti — cytotoxic T - lymphocyte — associated antigen 4 (CTLA - 4) or anti — programmed death 1 (PD - 1) / programmed death ligand 1 (PD - L1) agents seems to have some degree of clinical efficacy in advanced mucosal melanoma, although data are limited to smaller retrospective series or subset analyses of prospective trials.

Chemotherapy for MDS patients involves the use of medicines that kill cells cancer cells called cytotoxic agents.

This study illustrates the potential benefits of using GHRH antagonists for the treatment of cancers that are highly resistant to cytotoxic agents such as doxorubicin.

The control of these conditions often involves the long - term use of corticosteroids and other drugs such as immunosuppressive or cytotoxic agents.