In some individuals susceptible to high blood sugar, sulforaphane may be able to prevent (or even reverse)
some of the damage to blood vessel linings that can be caused by chronic blood sugar problems.
Neurological signs appear as a result
of damage to blood vessels in the brain and spinal cord associated with EHV infection.
Not exact matches
It creates a biological response, Murthy says, that leads
to chronic inflammation,
damaged tissue and
blood vessels, and an increased risk
of heart disease, arthritis and diabetes.
IDx - DR studied over 1 million eye images
to learn how
to recognize symptoms
of diabetic retinopathy, a condition that develops when high
blood sugar
damages retinal
blood vessels (SN Online: 6/29/10).
When the modified cells were injected into mice whose hind limbs had been injured, the tissue that regrew
to repair the
damage had three times the
blood vessel density
of similar tissue in mice given unmodified cells.
«But it's not falling that kills you; it's the landing,» Richard says: The abrupt pressure
of an impact is likely
to break open
blood vessels such as your aorta,
damage internal organs, and shatter your bones.
To look for the vessels, Dr. Reich's team used MRI to scan the brains of five healthy volunteers who had been injected with gadobutrol, a magnetic dye typically used to visualize brain blood vessels damaged by diseases, such as multiple sclerosis or cance
To look for the
vessels, Dr. Reich's team used MRI
to scan the brains of five healthy volunteers who had been injected with gadobutrol, a magnetic dye typically used to visualize brain blood vessels damaged by diseases, such as multiple sclerosis or cance
to scan the brains
of five healthy volunteers who had been injected with gadobutrol, a magnetic dye typically used
to visualize brain blood vessels damaged by diseases, such as multiple sclerosis or cance
to visualize brain
blood vessels damaged by diseases, such as multiple sclerosis or cancer.
When oxygen levels are restored
to normal, the eye senses it as a lack
of oxygen and responds by growing new
blood vessels, which often leads
to excessive growth and
damage to vision.
This happens because the loss
of blood flow in a
vessel causes the local oxygen level
to drop, which stimulates local production
of vascular endothelial growth factor, or VEGF, a protein which in most tissues causes the growth
of new
blood vessels to repair
damage.
Such antibodies, when attached
to DNA in complexes, get lodged in the walls
of arteries and in tissues
to cause inflammation that
damages blood vessels, skin, joints and the kidneys as part
of the most severe type
of lupus, systemic lupus erythematosus (SLE).
The spread
of damage from region
to region depends on the detailed pattern
of blood vessels in each patient and the amount
of blood they carry, both
of which vary greatly from person
to person.
An autopsy can trace the path
of a bullet through a body, or reveal microscopic
damage to blood vessels in the brain, or identify a lethal clog in an artery.
Even harder
to swallow was the claim that the material could transform, in a matter
of months, into whatever type
of body tissue had been
damaged — muscle, skin, or
blood vessel.
Any surgery carries the risk
of infection, and the procedure itself can actually
damage the
blood vessels, making them more vulnerable
to clots and aneurysms.
These conditions are associated with high
blood sugar, which can
damage the
vessels that supply
blood to vital organs and can also increase the risk
of heart disease and stroke.
Of those who venture into the skull, about half restrict themselves
to repairing
blood -
vessel damage on the brain's surface.
Milton Schiffenbauer
of Pace University in New York, US, says that by protecting against this
damage, polyphenols may reduce the
blood vessel inflammation thought
to promote cardiovascular disease.
Researchers from the UNC School
of Medicine have discovered that cells called fibroblasts, which normally give rise
to scar tissue after a heart attack, can be turned into endothelial cells, which generate
blood vessels to supply oxygen and nutrients
to the injured regions
of the heart, thus greatly reducing the
damage done following heart attack.
Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number
of reasons, including the ability
to regenerate its heart if
damaged, and because the transparency
of the embryos allows easy observation
of internal processes like
blood vessel development.
The sugar molecule attaches itself
to a protein called E-selectin, which is produced on the surface
of blood vessels near
damaged tissue.
Its chief role is
to probe for cells on the surface
of blood vessels that are exuding E-selectin as a signal that they are
damaged.
Years
of high
blood sugar can
damage blood vessels in the retina, leading
to diabetic retinopathy.
Because the new
blood vessels (also known as choroidal neovascular membranes) can be so
damaging, a wide variety
of treatments have been tried
to arrest their growth.
The force
of that
blood flow helps keep the cells that line the
blood vessels, called endothelial cells, healthy; when
blood flow is disrupted, such as during surgical procedures or a stroke, the
vessels start
to leak, which can cause a host
of inflammatory responses that lead
to cell
damage and disease.
In the small number
of people with signs
of both previous tissue
damage and a new clot in a
blood vessel, 14 per cent
of those given alteplase are likely
to have a hemorrhage, the team says.
Both
of these complications can cause significant
damage to blood vessels and nerve endings, making complications such as cardiovascular problems more likely.
Researchers at Emory University School
of Medicine were testing whether GM - CSF (granulocyte - macrophage colony stimulating factor), already used
to restore white
blood cell numbers during cancer treatment, could help heal
blood vessels damaged by atherosclerosis.
Now, scientists have discovered just how they do it without permanently
damaging blood vessels, which they slip into and out
of up
to 10 times each day.
With these findings we can now formulate a plausible hypothesis as
to why repeat head injuries
to young men in their teens and 20s lead
to personality changes later in adult life and dementia in old age: rotational head injury induces
damage, especially around
blood vessels, leading
to local tangle formation, followed by a slow spread
of destruction.
This happens because the loss
of blood flow in a
blood vessel causes the local oxygen level
to drop, which stimulates local production
of vascular endothelial growth factor, or VEGF, a protein that in most tissues causes the growth
of new
blood vessels to repair
damage.
Jansen is among those who think that a compromised network
of blood vessels in the brain triggers Alzheimer's by allowing toxins
to cross the
blood - brain barrier, potentially leading
to damage to neurons and inflammation.
In this vascular - decline hypothesis, the amyloid cascade is thought
to be a consequence
of the
damaged blood vessels and only part
of the process contributing
to Alzheimer's.
Through the UCSD Clinical Cardiovascular Cell Therapy program, Dib and collaborating cardiology faculty plan
to conduct clinical studies in a number
of areas, including the effectiveness
of adult stem cell transplant as a treatment for congestive heart failure; as a way
to minimize heart
damage after a heart attack; and in the formation
of new
blood vessels (angiogenesis)
to increase
blood flow
to the heart for patients experiencing chest pain.
These factors, together with
damage to the lining
of the
blood vessels, can lead
to permanent changes in the immune cells.
These drugs have been found
to increase oxidative stress (a type
of cell
damage), impair the body's ability
to digest fat and
damage blood vessels.
By stimulating the growth
of new
blood vessels, promoting anti-inflammatory effects, recruiting cells toward tissue regeneration and inhibiting further cell death, adult stem cells can restore some function
to damaged or diseased heart muscle.
Early observations suggesting that the virus might attack cancer in part by
damaging blood vessels that feed tumor growth led the SillaJen team
to strike up a collaboration with McDonald, an expert in tumor vasculature,
to investigate the virus's mechanism
of action in animal models.
With the loss
of the cushioning effect provided by free - moving collagen in the
blood vessels, the force
of the surge
of blood that is driven into the arteries by the pumping action
of the heart is carried directly
to organs like the kidneys and the brain,
damaging to the structures that filter our
blood and that connect the functional regions
of our brain, and putting us at risk
of a stroke.
Your fat tissue contains the most abundant source
of mesenchymal stem cells (MSCs) in your body — a class
of repair cells which have the ability
to decrease inflammation, repair or replace
damaged tissue while stimulating new
blood vessel growth for improved
blood flow.
When these
damaged blood vessels begin
to leak fluid near the center
of the retina, known as the macula, macular edema occurs.
Researchers generally attribute tissue thickening (and ensuing
damage to small
blood vessels)
to hyperactivation
of skin cells called fibroblasts.
This line
of investigation could eventually lead
to artificial
blood vessels, grown with patients» own cells or «off the shelf,» or biological / pharmaceutical treatments that promote the regeneration
of damaged blood vessels.
«They cause overactivity in the immune system, which can lead
to joint pain, fatigue, and
damage to the
blood vessels,» says Scott Zashin, MD, clinical professor at the University
of Texas Southwestern Medical Center in Dallas.
Flavonoids help maintain a healthy collagen structure by (1) decreasing
blood vessel permeability, thereby decreasing the influx
of inflammatory mediators into areas
of damage; (2) preventing free radical
damage by means
of their potent antioxidant properties; (3) inhibiting
damage to collagen tissue caused by enzymes that break down collagen; (4) inhibiting the release
of inflammatory chemicals; and (5) reinforcing the natural cross-linking
of collagen fibers
to make them stronger.
Men may experience erectile dysfunction due
to blood vessel damage, and some can have a problem with retrograde ejaculation, in which semen travels
to the bladder instead
of through the tip
of the penis.
Exposure
to UV rays causes pigmentation, prominent
blood vessels, wrinkles and other signs
of premature ageing as it
damages skin's constituent collagen and elastin.
The anti-inflamatory properties found in this cruciferous vegetable may prevent the
damage done
to the walls
of blood vessels.
«High
blood pressure
damages blood vessels throughout the body, making them more susceptible
to developing clots,» says Lewis Morgenstern, MD, director
of the University
of Michigan Stroke Program.
Heat therapy dilates the
blood vessels of the muscles which increases the flow
of oxygen and nutrients
to the muscles, helping
to heal the
damaged tissue.
If the
blood vessels leading
to the penis are
damaged in any way, often due
to atherosclerosis (hardening
of the arteries), dilation becomes a problem.