Sentences with phrase «of damage to the heart muscle»

Acute myocardial infarction, commonly known as a heart attack, can be classified according to the extent of damage to the heart muscle.

The results from certain tests can provide accurate data about the degree of damage to the heart muscle.

Not exact matches

The PDR goes on to specify in excruciating detail the toxic potential of this drug: liver damage, kidney destruction, heart muscle compromise, pulmonary failure, gastrointestinal pathology, and bone marrow suppression.

In this case, part of the focus was on tests to assess levels of troponin, a protein whose components increase in the blood when heart muscle is damaged.

For a high - risk heart failure patient, Farra says, it might be possible for the device to monitor the heart for signs of a heart attack and release drugs to decrease damage to the heart muscle during a cardiac event.

«It is our hope that Dr. Yin's research will lead to additional potential therapeutic agents like ZF143 to reactivate mechanisms for the repair and regeneration of damaged heart muscle tissue in humans.»

A team of scientists from the National Institutes of Health has discovered biological mechanisms that appear to prevent damage to the heart muscle's «power grid,» the network of mitochondrial circuits that provide energy to cells.

The day after his disciplinary dismissal from University of Tokyo for «damaging the university's honor or credibility,» Hisashi Moriguchi maintained in an interview with ScienceInsider that he really did participate in a groundbreaking experiment to treat a heart disease patient with cardiac muscle cells derived from the patient's own induced pluripotent stem (iPS) cells.

Normally, the inflammatory response to tissue damage after infarction — death of muscle tissue in a heart attack — has two stages.

They also demonstrated that damage to this protein leads to excess growth of heart muscle, a decrease in function, and severe pathological growth of heart muscle.

Exploiting that power, researchers are now using microRNAs to convert the scar tissue of damaged hearts into healthy muscle cells, opening the door for a better therapy after heart attacks and heart failure.

Heart attacks are divided into two types according to the severity of cardiac muscle damage.

A STEMI (ST segment elevation myocardial infarction) heart attack happens when an artery is completely blocked by the blood clot, which causes damage to virtually all of the heart muscle supplied by that artery.

What's more, by selectively deactivating certain PAMs within the matrix, the team mimicked the kind of damage that happens to the heart muscle under certain disease conditions.

A heart attack occurs when blood flow to an area of the heart is blocked by a narrowed or completely obstructed coronary artery, resulting in damage of heart muscle.

Earlier studies in STEMI patients showed that ischemic postconditioning improved ST - segment resolution — an important marker of arterial blockage on electrocardiogram — reduced damage to heart muscle, and in some patients limited the extent of reperfusion injury.

New research at Rockefeller University and Columbia University suggests these small molecules may be able to relay valuable information about damage to the heart: Scientists in Thomas Tuschl's Laboratory of RNA Molecular Biology have linked an increase in certain microRNAs circulating in the blood with injury to cardiac muscle.

If clinicians fail to reopen occluded coronary arteries after a heart attack within an appropriate time frame, the heart muscle is permanently damaged because of the long - term interrupted oxygen supply.

Anthracycline drugs, such as doxorubicin, are known to cause heart failure because they cause changes in the DNA structure of the heart muscle cells, leading to irreversible cardiac damage.

Together, the teams of Drs. Srivastava and Ding are confident that they will soon find a way to eliminate the need for genes entirely, thus using only a cocktail of small molecules to generate beating heart muscle and regenerating damaged hearts.

In mice with heart damage similar to a heart attack in humans, the three factors not only created new muscle, but also improved the pumping of the heart.

About 720,000 people experience a heart attack annually in the United States, which means that hundreds of thousands of people each year could benefit from a therapy to repair and regenerate damaged heart muscle.

Dr. Srivastava's lab has leveraged the body of knowledge from cardiac developmental biology to reprogram non-muscle cells in the mouse heart directly into cells that function like heart muscle cells, effectively regenerating heart muscle after damage.

Friedreich's ataxiais an inherited disease that causes progressive damage to the nervous system, resulting in symptoms ranging from gait disturbance to speech problems; it can also lead to heart disease and diabetes.The ataxia of Friedreich's ataxia results from the degeneration of nerve tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs.

By stimulating the growth of new blood vessels, promoting anti-inflammatory effects, recruiting cells toward tissue regeneration and inhibiting further cell death, adult stem cells can restore some function to damaged or diseased heart muscle.

The objective is to prevent progression of the coronary artery blockages, thus preventing heart attacks and further damage to the heart muscle.

After a heart attack, testing is usually done to determine the extent of heart muscle damage.

«When heart muscle is damaged, the body is unable to repair the dead or injured cells,» explained Deepak Srivastava, MD, director of the Gladstone Institute of Cardiovascular Disease and a co-founder of the new company.

The application of these therapies could range from the repair of heart muscle damaged by heart attack to the repair of sports - related bone, cartilage and muscle injuries.

heart attack Permanent damage to the heart muscle that occurs when one or more regions of it become starved of oxygen, usually due to a temporary blockage in blood flow.

To repair heart muscle in a mouse, researchers inject adult stem cells into the muscle of the damaged wall of a mouse heart.

If the affected heart muscle is damaged it can heal, but it may not be able to pump blood like it used to because of scar tissue.

CINCINNATI - Scientists used an experimental targeted molecular therapy to block a matrix - forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

Thanks to new technological advances, the test is now widely used to diagnose numerous cardiovascular conditions, including congestive heart failure, coronary heart disease, and the extent of heart muscle damage caused by heart attacks (some of which may go unrecognized with less sensitive technology).

Turns out, Alexander - Wright's neck pain and exhaustion had been early warning signs of a heart attack (in which blood flow to a section of heart muscle is blocked, causing damage there).

The authors said their findings show that poor muscle health should be added to the known complications of type 1 diabetes, along with nerve damage, heart disease and kidney disorders.

If a heart attack is treated promptly — within 90 minutes of when symptoms start — the damage to heart muscle may be minimized.

Regular exercise lowers cholesterol, increases heart muscle strength (which improves the volume of blood it can move), improves blood supply (thereby oxygen to the heart), reduces blood pressure, inhibits blood clots, minimizes damage due to stress, and reduces overall body fat.

The compartments aren't able to expand as much as they're supposed to be able to under increased pressure and you get a ton of pressure within the muscles and as that happens, it compresses nerves and blood vessels and decreases blood flow which means that the tissues inside that compartment don't get enough oxygen rich blood and they are essentially oxygen starved and they become damage the same way that your heart, if oxygen starved, undergoes a heart attack and this can not be painful but can be damaging to the muscles.

Touted to keep heart disease at bay, statin drugs are now known to be a cause of serious memory loss fuzzy thinking, learning difficulties, fatigue, muscle damage, and even diabetes.

Unfortunately due to poor nutritional habits, high stress levels, regular use of alcohol and other factors deficiency of this vitamin is very common today and leads to tiredness, heart complications, low mood, irritability, confusion, muscle weakness, indigestion, appetite problems and nerve damage.

In particular, they focus on the diagnosis and treatment of congestive heart failure, damage to the heart muscle or valves, cardiac arrhythmias, congenital defects, diseases of the pericardium, high blood pressure, coughing and other breathing issues.

• Congestive heart failure • Damage to the heart muscle or valves • Coughing and other breathing problems • Congenital (present at birth) defects • Cardiac arrhythmias (problems with the rate and / or rhythm of your animal's heart)

Studies in rabbits indicate that several things can happen under extreme or prolonged stress including; a drop in body temperature, a drop in blood pressure, damage to the kidneys, loss of appetite, stomach ulcers, cardiomyopathy (heart muscle disease) and ultimately death.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)

The effects of the heartworm are to physically block the normal blood flow through your heart and to damage the lining of the heart muscle inside the right chamber.

† Myocardial Infarction (MI, Acute Myocardial Infarction, AMI, Non-ST Segment Elevation Myocardial Infarction, STEMI, Heart Attack): An acute interruption of vascular perfusion of any portion of the myocardium (muscles of the heart) due to either an occlusion of a coronary artery or to vascular spasm causing damage to the myocarHeart Attack): An acute interruption of vascular perfusion of any portion of the myocardium (muscles of the heart) due to either an occlusion of a coronary artery or to vascular spasm causing damage to the myocarheart) due to either an occlusion of a coronary artery or to vascular spasm causing damage to the myocardium.