Sentences with phrase «of damage to the spinal cord»

The rate and extent of damage to the spinal cord and brain following spinal cord injury have long been a mystery.
Depending on the severity of injury and location of damage to the spinal cord, back trauma can result in total or partial paralysis, loss of movement, loss of feeling and other injuries.
Seeing a medical professional right away will help to ensure that the extent of the damage to your spinal cord is contained and that your health is not in jeopardy.
A spinal cord injury consists of damage to the spinal cord that results in a loss of function, such as mobility or feeling.

Not exact matches

Neurosurgery to deal with brain, spinal column, spinal cord, and peripheral nerve damage may be needed within hours or days of birth.
Later complications include weakness and numbness in 4 to 18 per 10,000 women, most of which resolve spontaneously within three months.65 — 69 Longer - term or permanent problems can arise from: damage to a nerve during epidural placement; from abscess or hematoma (blood clot), which can compress the spinal cord; and from toxic reactions in the covering of the spinal cord, which can lead to paraplegia.70
They found I had in fact damaged my spinal cord I was in fact Paraplegia, not because I could not walk but due to the loss of bowel and bladder.
Eligible conditions include cancer, HIV / AIDS, ALS (Lou Gehrig's Disease), Parkinson's Disease, multiple sclerosis, damage to the nervous tissue of the spinal cord with objective neurological indication of intractable spasticity, epilepsy, inflammatory bowel disease, neuropathies, Huntington's Disease, or others as added by the New York State Commissioner of Health.
Large quantities of these reverted cells could be used to treat anything from spinal cord injury to liver damage without the risk of tissue rejection, said Robert Weinberg, a biologist at the Massachusetts Institute of Technology's Whitehead Institute for Biomedical Research and co-author of a study appearing in Cell.
In 2002 ethnobotanist Paul Cox from the Institute for Ethnobotany at the National Tropical Botanical Garden in Kalaheo, Hawaii, and neurologist Oliver Sacks from the Albert Einstein College of Medicine in New York City introduced a shocking theory about how Chamorros might be ingesting enough BMAA to damage neurons in the brain and spinal cord.
Studies in rats and dogs have already demonstrated that olfactory ensheathing cells (OECs), which insulate bundles of nerve cells, can help repair damage to the spinal cord and nerves leading to animals» paws.
The government money will be allocated to two areas: rare or incurable diseases for which there is little incentive for private investment, such as spinal cord damage; and common chronic conditions, such as arthritis, for which the aim is to help South Korean companies to capture part of the large potential market for treatments.
New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury.
It also inflicts damage in the nerve pathways extending from the spinal cord out to the muscles of the body.
The treatment not only led the spinal cord cells to produce and secrete ChABC in large quantities over areas spanning the injury epicenter, it helped to maintain the overall health of the damaged spinal cord and restored hind limb function in the animals within 12 weeks.
But applying this method to humans would require multifunctional implants that could be installed for long periods of time on the spinal cord without causing any tissue damage.
Researchers envision the e-dura being used in people with spinal cord injuries, as a brain implant and even to correct nerve damage in other parts of the body.
The protein itself has been known to researchers for some time as a result of research on zebrafish, where it plays an important role in the healing process following damage to the spinal cord.
These stroke - related alterations in the cervical spinal cord indicate pervasive and long - lasting BSCB damage that would severely affect spinal cord function, wrote the researchers, adding that the widespread microvascular impairment in the gray and white matter of the cervical spinal cord aggravated motor neuron deterioration and had the potential to cause motor dysfunction.
A team of researchers at the University of South Florida investigating the short and long - term effects of ischemic stroke in a rodent model has found that stroke can cause long - term damage to the blood - spinal cord barrier (BSCB), creating a «toxic environment» in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.
«This study, carried out using laboratory rats modeling stroke, demonstrated that ischemic stroke — in both its subacute and chronic stages — damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.
And by creating personalized organoids from the reprogrammed cells of patients, scientists could study disease in a very individualized way — or maybe even use organoid structures to replace certain damaged tissues, such as in the liver or spinal cord.
Instead of focusing his energy on generating neural regrowth across spinal cord lesions that lead to paralysis, his approach relies on the plasticity of the nervous system, this incredible ability of the nervous system to adapt to damage.
Microglia are present throughout the brain and spinal cord, are constantly monitoring their environment, and can be switched on or activated to perform different functions such as control inflammation, destroy pathogens, clean up the debris from dead or damaged cells, and seal off the site of an injury.
Oligodendrocyte death, occurring after a spinal cord injury, activates a process called de-myelination that results first in damage to surviving neuronal connections and finally in death of the affected neurons.
The researchers concluded that the presence of CBD or THC restrains the immune cells from triggering the production of inflammatory molecules and limits the molecules» ability to reach and damage the brain and spinal cord.
This promises to make proton therapy an option for thousands more cancer patients by reducing the risks of healthy tissue being damaged during treatment, particularly in vulnerable parts of the body such as the brain, eye and spinal cord.
In the future, medical researchers anticipate being able to use technologies derived from stem cell research to treat cancer, spinal cord injuries, and muscle damage, amongst a number of other diseases and impairments.
«This solves a long - running mystery of how a gene mutation damages the neurons that carry information from the spinal cord to our muscles, resulting in a range of sensory and movement problems,» says Samuel Pfaff, a neuroscience professor at the Salk Institute and one of the senior authors on the paper with Xiang - Lei Yang, a professor at TSRI.
Damage to astrocytes — star - shaped cells found in the brain and spinal cord — is found in many neurodegenerative conditions, but it's been unclear exactly what role astrocyte dysfunction plays in the development of disease.
To prevent collateral damage to precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrieTo prevent collateral damage to precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrieto precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrier.
These problems are caused by a type of white blood cells called T cells that, after becoming activated, find their way into the brain and attack the protective covering — myelin — of neurons in the brain and spinal cord, causing inflammation and damage to the central nervous system.
The study suggests that activation of muscle spindles is essential to promote the recovery process of damaged neuronal networks after spinal cord injury.
A particular type of macrophage known as microglia are found throughout the brain and spinal cord — in progressive forms of MS, they attack the CNS, causing chronic inflammation and damage to nerve cells.
Damaged axons in the brain and spinal cord of mammals don't regenerate, and spinal cord injuries can therefore lead to permanent paralysis.
Ultimately, the enhanced understanding of central nervous system organization that has derived from the research of these three scientists may lead to new and more effective ways to repair diseased or damaged circuits embedded in the human brain and spinal cord.
Whether and to what extent damage to the spinal cord alters the body representation, however, is still a matter of dispute among experts and doctors.
The face is cut and bruised by direct impacts, but damage to the brain is caused largely by rotational acceleration of the cerebral cortex around the much smaller midbrain and spinal cord.
This damages nerve cells by blocking their ability to make the proteins needed for synaptic function and leads to the death of neurons in the brain and spinal cord.
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Friedreich's ataxiais an inherited disease that causes progressive damage to the nervous system, resulting in symptoms ranging from gait disturbance to speech problems; it can also lead to heart disease and diabetes.The ataxia of Friedreich's ataxia results from the degeneration of nerve tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs.
Furthermore, the success of this project can lead to the development of novel axon - regenerating therapeutics that could transform the clinical treatment of angle - closure glaucoma and other types of optic neuropathies, as well as have the potential to be adapted to regenerating the long - distance axonal projections damaged by spinal cord injury, brain trauma, and white matter stroke.
If a disease damages one portion of a motor pathway, for example, it might be possible to stimulate neurons further down the circuit, closer to the spinal cord, to initiate sequences of action.
We are very excited by the potential of this material for cardiac applications but the capacity of the material to deliver physiological electrical stimuli while limiting infection suggests it might have potential in a number of other indications such as repairing damaged peripheral nerves or perhaps even spinal cord.
Treatment for damage to peripheral nerves, which extend from the brain and spinal cord out to the rest of the body, is often challenging.
Todd McDevitt, PhD, who helped acquire the microscope, is using the Lightsheet to track the integration of neurons created from stem cells into damaged mouse spinal cords.
For more than a century, scientists thought that glial cells were responsible for scar formation; now, however, a paper published in Science shows that spinal cord scar tissue largely derives from a completely unexpected type of cell called a pericyte, opening new opportunities for the treatment of damaged nerve tissue.Lesions to the brain or spinal cord rarely heal fully, which leads to permanent functional impairment.
Brachial plexopathy occurs when there is damage to the brachial plexus - the bundle of nerve which exit your spinal cord at the base of the neck, between the C5 and T1 vertebrae.
Upon re-feeding, new progenitor stem cells were created that repopulated the immune systems of the affected mice, and aided in repairing the damage to the brain and spinal cord.
Uncontrolled, excessive inflammation contributes to the secondary tissue damage of traumatic spinal cord, and HMGB1 is highlighted for initiation of a vicious self - propagating inflammatory circle by
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