Sentences with phrase «of damaged proteins»

In this way, they help to prevent the accumulation of damaged proteins whose folding is disrupted by the increased temperature and that potentially become toxic.

This could be one of the mechanisms responsible for the reduced regeneration capacity in the aged brain as stem cells that retain larger amounts of damaged proteins require longer for the next cell division.

The barrier prevents retention of damaged proteins in the stem cell daughter cell keeping the stem cells relatively clean.

So to sum this up keep in mind that you have to serve four «masters»: hydration, restoration of metabolized carbohydrate, restoration / repair of damaged proteins, and remodeling proteins.

Malaria parasites generate a lot of damaged proteins as they switch from one life stage to another and are very reliant on their proteasome, making it an excellent drug target,» Prof Tilley said.

Protein aggregates that form after a cell is exposed to high, non-lethal temperatures appear to be part of an organized response to stress, and not the accumulation of damaged proteins en route to destruction.

This leads to reduced asymmetry of damaged protein segregation with increasing age of the stem cell.

This leads to reduced asymmetry of damaged protein segregation (on the right).

Such interventions are designed to maintain vascular, metabolic, skeleto - muscular and other aspects of health, in part, through preventing increased flux of damage to proteins and increased steady - state levels of damaged proteins.

The prize was for his work on autophagy, a kind of cellular housekeeping that helps clear the cell of damaged proteins and other potentially toxic debris.

Professor Mundree said autophagy was primarily a survival mechanism that allowed removal of damaged proteins and recycling of nutrients, however, prolonged stress could result in excessive autophagy and death.

«It could have something to do with an accumulation of damaged proteins within the cell or with breakdown in the proteins that control DNA replication and repair — we're really not sure at this point.

A diffusion barrier regulates the sorting of damaged proteins during cell division.

Cell biologist Yoshinori Ohsumi of the Tokyo Institute of Technology has received the prize for his work on autophagy, a method for breaking down and recycling large pieces of cellular junk, such as clusters of damaged proteins or worn - out organelles.

Using antibodies to identify fragments of the damaged proteins, Chapman's group showed that toxin molecules were moving to nerve cells in wells that had not initially received the harmful molecules.

The Sheffield team led by Dr Kurt De Vos and Dr Andy Grierson investigated the role of the C9orf72 protein in nerve cells and found it regulates the initiation of a vital process called «autophagy», which helps the cell to dispose of damaged proteins and cell parts, and recycles cell nutrients.

Turmeric, one of the main curry ingredients contains curcumin which helps reduce the build - up of damaging proteins that cause Alzheimer's.

Repair and rebuilding occurs through the breakdown of damaged proteins and the construction of new ones and nutrition has a huge influence on these processes.

Singlet oxygen has been implicated in biological systems and is capable of damaging proteins, lipids and DNA and therefore is thought to be involved in the pathogenesis of numerous diseases.

These proteasomes usually rapidly stop functioning, leading to the accumulation of damaged proteins that further impair cell function, contributing to the vicious cycle that leads to cell death.

Accumulation of protein damage in ageing, that is, increased steady - state levels of damaged proteins occurs as a consequence of: (i) increased rates of protein damage — linked to increased rate of damaging agent formation and decreased anti-glycation and oxidant defences, (ii) decreased rates of repair of damaged proteins, and (iii) decreased rates of proteolysis of damaged proteins.

MPS is the removing or repairing of damaged proteins and building of new proteins that are replicas of the original.