Sentences with phrase «of different biomarkers»

In terms of applications for the system, since the specific target detection of microgels can be easily tuned, it can be applied to a wide range of different biomarkers thanks to its barcode structure.

«To do this, we developed computer models of exoplanets which simulate the abundances of different biomarkers and the way they affect the light shining through a planet's atmosphere.»

«But much more research is needed,» he adds — especially comparisons of different biomarkers at different time points after injury — to develop a more reliable blood test for concussion.

Each reservoir has specific amounts of different biomarkers, so oil biomarkers serve as identifiers much like human fingerprints.

Not exact matches

That last step is the most important, but also one of the most challenging because «when you try to sample a large population of people who you already know have a certain disease, like cancer, it's really difficult to pinpoint all the different biomarkers that will make you fairly sure of the person's illness is detected regardless of environmental conditions,» he says.

This is because a person living in the heavy smog of L.A. will have adapted to that environment and metabolize a different set of biomarkers than a rural dweller.

Biomarker data management platforms become even more essential as different types of biomarkers are analyzed together, such as proteins and miRNAs.

A composite biomarker score, created by combining two different ratios, predicted the presence or absence of A-beta plaques in the brain with about 90 percent accuracy in both groups of patients, the researchers found.

Sahakian agrees that other subtypes of depression are likely to be identified with different biomarkers.

Yet the biomarkers of Alzheimer's pathology currently being investigated and developed are at different stages of development.

A second study, out of MIT, used principles of computer engineering to design a molecular logic circuit that senses six different biomarkers, seeking out a chemical pattern unique to one type of cancer.

By identifying and profiling molecules that differ between different forms of dengue, the researchers lay the foundations for finding biomarkers present at early - stage dengue that are able to predict disease development.

Hariri said he hopes that other researchers looking for biomarkers of mental illness will begin to consider methylation above and beyond DNA sequence - based variation and across different tissues.

They say that the system can be constructed with more than five different aptamers, allowing detection of multiple biomarkers at once.

As different cancers express different biomarkers, it might be possible to modify the molecular structure of the ruthenium molecule to target different types of cancer cell.»

Association of a protein biomarker with any given disease process, for example, needs to be assessed in terms of disease - independent, confounding factors that may modulate protein expression levels among different individuals.

A similar principle is used in the medical field to detect biomarkers for different kinds of health conditions, including cancer, by taking breath samples.

If the findings hold up across different autoimmune diseases, it's possible that the characteristic patterns of Xist localization could be used as a disease biomarker, enabling earlier diagnoses and treatment.

By applying a powerful method that was developed for detecting fecal matter in drinking water, geoarchaeologist Ainara Sistiaga of the University of La Laguna in Tenerife and geobiologist Roger Summons of the Massachusetts Institute of Technology in Cambridge have detected the biological signature, or biomarkers, of meat and plants in the sediments containing fossilized feces from five different places at El Salt.

Tumor tissues of six patients were stained for two different tumor biomarkers (CA IX and Topo - I) before and after treatment with CRLX101.

So biomarkers for glaucoma would be just wonderful to have for a couple of different reasons.

This new biomarker discovery technology can be applied to different forms of glaucoma in the future to identify autoantibody biomarkers for early detection, diagnosis, subclassification, therapy assessment, and prognosis.

Dr. Andrew Huberman: A biomarker can mean many different things, and when we set out to find a biomarker, we discussed whether or not this was going to be some way of imaging into the eye and seeing whether or not the retina was sick, whether or not it was going to be based on a blood draw, or some other measure.

And we are now taking advantage of the different skills that we have in the consortium to try to interpret these and see how they evaluate the potential to be a biomarker of either progression or an early diagnostic tool.

«We see this atlas providing a foundation for investigating many different questions about the pathology in the gut, effects of drug - induced gut toxicities and for identifying and examining important cells, interactions, and biomarkers,» said Xavier, who is also chief of gastroenterology and director of the Center for the Study of Inflammatory Bowel Disease at MGH.

As part of their ongoing research, Ratain and O'Donnell are actively seeking out genetic biomarkers that shed light on how cancer patients will respond to different treatments.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Previous experience also includes a role as Senior Scientist with Eli Lilly and Company where she was part of the Pharmacogenomics and Translational Medicine Group in charge of discovering and validating genetic / genomic biomarkers in different therapeutic areas (oncology, cardio - metabolic and neurosciences).

Researchers are also trying to learn about: - The level of MM - 121 that remains in the human body at different time points when MM - 121 is combined with docetaxel or pemetrexed - The relationship between the biomarker, heregulin, and cancer cell growth (disease progression) in people dosed only with docetaxel or pemetrexed.

Research on vaccine biomarkers, including in - depth comparative analysis of data from different platforms, large - scale RNA sequencing, harmonisation of standard operating procedures (SOPs) for sample, microarray and data analysis, as well as transcriptome mapping (more than 1400 samples analysed).

Because different tissue antigens are targeted in different diseases, and some conditions target a diverse array of autoantigens, it is challenging to develop biomarkers of tolerance.

miR - 9551 also has potential as a biomarker of resistance in different nematode species.

These studies have opened up new avenues for therapeutic intervention throughout the different stages, and have also aided in the identification of biomarkers that can help in determining disease diagnosis and prognosis.

Those breakthroughs include the development of new screening methods to search for effective drugs, new ways to treat hepatitis B using different approaches to shut down the virus, a new blood biomarker that aids in the early detection of liver cancer, and a promising drug that selectively kills liver cancer cells in animal studies.

Some of the gluten - sensitive people included in Dr. Fasano's study had minor intestinal damage (classified as Marsh 1 or 2), but that damage had different biomarkers than those seen in celiac disease.

In fact, as you'll see from many of these studies researches are trying to keep total fat constant so they can measure the differences in biomarkers from different diets and see what works.

Researchers followed a subset of 1,139 subjects and found that those with the greatest increases in urinary polyphenols had significantly lower levels of five different biomarkers of inflammation, such as adhesion molecules, interleukin, tumor necrosis factor alpha, and monocyte chemotactic protein.

Although both study groups were eating the same amounts of calories, the different macronutrient compositions in the two groups led to very different body composition and biomarker changes.

Some studies have reported a significant reduction in plasma glucose and hemoglobin A1c levels, 52,53 while others have reported no effect on any aspect of glucoregulatory control.54 Given that dietary polyphenols are rapidly metabolized, one explanation for the discrepant findings between these studies may have been the measurement of the effects of tea on biomarkers at different times after its consumption.

Evaluation of two different biomarkers for use in the assessment of toxic chemical exposure in California sea lions (Zalophus californianus).