Sentences with phrase «of disease etiology»

To create cell models for the discovery of disease etiology, progression, and treatment, isogenic cell lines can be created from healthy or sick individuals, then compared (Figure 1).

«These guidelines will provide physicians with a tool for basic understanding of the disease etiology and possible complications to look for when managing a patient.

Not exact matches

In spite of the fact that there is no clear etiology for the disease, most people now assume alcoholism is indeed a disease.

Congenital heart disease is the underlying etiology for many of these valvular lesions and cardiomyopathies.

Rigas A, Rigas B, Blassman M, et al. «Breast - feeding and maternal smoking in the etiology of Crohn's disease and ulcerative colitis in childhood.»

According to Olsen, a trend in academia and industry will be to establish that Parkinson's disease for example, is not one disease, but perhaps 10, and to develop individualized treatments based on understanding of etiology.

These findings also will help investigators to understand the etiology of common complex diseases because we can anticipate more functionally significant variants to influence diseases with a stronger environmental component, while uncommon variants may be more important for diseases with a weak environmental contribution.

The program seeks to attract students interested in the etiology, pathogenesis, and treatment of Parkinson's disease.

The role of weight in ovarian - cancer risk emerges from an analysis of data on some 68,000 women participating in one of three major ongoing investigations: the New York (City) University Women's Health Study, the Northern Sweden Health and Disease Study in Umea, and the Diet in the Etiology of Breast Cancer Study in Milan, Italy.

These findings causally link sleep deprivation to the etiology of biological aging, and further supports the hypothesis that sleep deprivation may be associated with elevated disease risk because it promotes molecular processes involved in biological aging.

In Poirier's case, his multidisciplinary approach to the understanding of the etiology of neurodegenerative diseases gives him an edge.

«Remarkably little research funding has been made available to study the etiology, pathophysiology, and effective treatment of this disease, especially given the number of people affected,» the authors noted.

Lung branching abnormalities underlie the etiology of many lung diseases including pulmonary hypoplasia (PH), a congenital state of incomplete development of the lungs.

«Although our hypothesis addresses the etiology of hypertension in footballers acutely, it could also have important implications on understanding the development of chronic disease long - term, and thus may improve the quality of football players» lives upon retirement from the game,» said Cameron G. McCarthy, M.S., study author from the Department of Physiology at Georgia Regents University in Augusta, Georgia.

The IHVR (Institute for Hepatitis and Virus Research) through a DCED (Department of Community and Economic Development) Innovation Grant from the State of Pennsylvania called «Talent Scout for Technology» — PI: «The case for an infectious etiology of late onset Alzheimer's disease «(01/01/11 — 12/31/11).

The study of BIN1 in the brain is a new area of research and determining the mechanistic link between this risk factor and AD etiology disease is important.

Collectively, these will advance the understanding of the role ChrX plays in the etiology of age - related diseases, which will also have an important positive impact on our understanding of sex differences in aging processes.

Dr. Torkamani's research covers a broad range of areas centered on the use of genomic technologies to identify the genetic etiology and underlying mechanisms of human disease in order to define precision therapies for diseased individuals.

«It is difficult to overstate the centrality of protein folding and its perturbation in the etiology of major diseases, including neurodegenerative syndromes.»

This is an interesting and important paper for basic understanding of mitochondrial DNA dynamics and the etiology of mitochondrial disease.

I look for genes, pathways, and candidate mutations associated with a disease, in order to understand the mechanism and the etiology of a disease, which may eventually lead to new therapeutic targets.

«Intuitively, one might expect disease - causing variants to cluster into key pathways that drive disease etiology [the causes of disease],» they write.

Neuroprotection, etiology and treatment of Parkinson's disease, mitochondrial cytopathies, abnormalities of the mitochondrial genome

Dr. Rotimi's research focuses on the etiology of complex diseases and health disparities.

There is increasing evidence that rare and unique mutations have a significant role in the etiology of many diseases such as autism, congenital heart disease, and cancer.

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Funding of clinical research, disease and health related projects and research related to the understanding of the etiology and treatment of diseases Recurrence of the programme: yearly

Such complexity is reflected by the involvement of various brain regions and multiple pathways in the etiology of neurodegenerative diseases that render single drug target approaches ineffective.

Through the use of animal models, researchers have sought to understand the etiology of post-treatment Lyme disease syndrome (PTLDS), namely whether or not the spirochetes persist post-treatment and could thus contribute to chronic symptoms.

It is classified as a distinct primary cardiomyopathy with a genetic etiology and may be an isolated finding or may also be associated with other forms of structural congenital heart disease (Jenni et al., 2001).

Comparison of microbiome data from the alcohol model, BDL, CCl4, and an obesity model noted that there was no common liver disease microbiome, suggesting that the intestinal microbiome differs by etiology of liver disease.

Because the symptoms characterizing CFS resemble those of infectious diseases, many studies have investigated a viral etiology in CFS.

In both research and clinical settings, the majority of patients with rare disease lack a clear etiology after exome and genome sequencing.

The spirochetal etiology of Alzheimer's disease: A putative therapeutic approach.

Dr. Seidman has investigated the molecular etiology of human diseases, with a focus on congenital heart disease, familial hypertrophic cardiomyopathy, and familial dilated cardiomyopathy.

Other cognitive diseases linked to paternal age include mental retardation of unknown etiology and Alzheimer's disease, and there is a strong relationship between paternal age and autism.»

Neurologic Post Treatment Lyme disease (nPTLS) and Chronic Fatigue (CFS) are syndromes of unknown etiology.

To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome - wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD.

Expression of clusterin, a protein implicated in other etiologies of cardiovascular disease, was assessed in canine and murine mucopolysaccharidosis type I aortas via Western blot and in situ immunohistochemistry.

As well as monitoring maternal nutrition during pregnancy, the study will regularly assess their children's health and developmental status during the first 10 years of life, in order to elucidate the role of environmental factors in the etiology of allergic disease.

Heparan sulfate - mediated inflammation can not be the sole etiology of MPS cardiovascular disease pathogenesis.

More specifically, controversy continues to surround the theories that 1) dietary fat, saturated fat, and cholesterol cause heart disease, obesity, diabetes and cancer and should be replaced in the diet with polyunsaturated vegetable oils; 2) a diet high in carbohydrates will reduce the risk of chronic disease; and 3) excessive sodium intake is the primary variable in the etiology of hypertension, a risk factor for heart disease.

When you look at the etiology of most kidney diseases the approach we took with Pete addressed every damn variable all at once: autoimmunity, elevated insulin and growth factors, AGE's... did I miss anything?

Our air, water and soil contain carcinogenic, neurotoxic and genotoxic chemicals that have been implicated in the etiology of the diseases that kill us: heart disease, cancer, diabetes and Alzheimer's disease to name a few.

(30 - 31) Sarcoidosis A unusual lung disease of unknown etiology called Sarcoidosis is linked to gluten sensitivity.

In preparation for TACT 2, Dr. Lamas studied the role of metal toxicity and other environmental factors in the etiology of cardiovascular disease.

«do not address the underlying pathophysiology of type 2 diabetes» is a general statement that could apply to any pill, injection or surgery in that just about any intervention outside of lifestyle modification doesn't address the etiology of the disease.

The association between caffeine and hormones is of interest, because persistent elevation or insufficiency of reproductive hormones during the premenopausal years may not only contribute in the long term to the etiology of certain diseases, such as breast, endometrial, and ovarian cancers (11 — 14), but may also affect ovulatory function in the short term (15, 16).

With bitters, digestive enzyme secretions are increased, helping to promote the complete breakdown of nutrients into their absorbable units, preventing gas formation when large molecules are acted upon by bacteria further down the small intestine.2, 11 The complete breakdown of proteins is particularly important, as the cross reactivity of immune cells between undigested protein molecules and intestinal cells plays an important role in the etiology of conditions such as celiac disease.15 Insulin and glucagon secretions are stimulated, helping to stabilize blood sugar levels.3, 11 Many bitters formulations have been traditionally used in the treatment of type 2 diabetes, and it is interesting to point out that many naturally sweet substances are often paired with some bitterness in nature.4, 11 Herbalist Jim McDonald hypothesizes that our cravings for sweetness may mask cravings for bitterness for this reason.4

Given the well - established role of steroid hormones in breast cancer etiology for postmenopausal women, these findings may have important health implications» Tumor growth from these hormone imbalances is also evident «A dramatic increase in estrogen - dependent malignant diseases, such as ovarian, corpus uteri, breast, testicular and prostate cancers has been recognized.