Sentences with phrase «of disease resistance genes»

The researchers discovered that a large portion of disease resistance genes were lost in the domestication of watermelon.

Not exact matches

The advent of rice varieties bearing genes with resistance to the disease has changed the perception about the disease: the incorporation of host - plant resistance genes in rice varieties, their adoption and deployment in the world's main rice - producing environments is probably one of the most significant evidences of the role of plant pathology in agricultural development.

In terms of biodiversity, organic farming takes into account gene adaptation, local ecosystems and species to improve disease resistance, soil, gene pools and local wildlife habitats.

No doctor wants to ignore an opportunity to save a patient from infectious disease, yet much of what is prescribed is probably unnecessary — and all of it feeds the spread of resistance genes in hospitals and apparently throughout the environment.

Bacteriophages, or viruses that infect bacterial pathogens, may also act as vectors of virulence or of antibiotic resistance genes, ultimately making bacterial disease worse for the host.

He had noted subtle variations between the resistance genes he pulled out of soil organisms and their doppelgängers in disease - causing bacteria.

The more diverse the genes of the MHC, the more effective it is at conferring disease resistance, and in a variety of animals individuals with diverse MHCs are more likely to be chosen as a sexual partner.

The sequences provide researchers access to 96 percent of all peanut genes and provide the DNA map needed to more quickly identify and genetically tag genes that confer desirable traits, such as drought - and disease - resistance.

Genetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasing it.

The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly nDisease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly ndisease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).

There is a need for both innovative, durable disease resistance genes ad smart strategies for the deployment of resistant crop varieties.

What is so encouraging about the first successful unpicking of a wheat gene that confers resistance to a devastating fungal disease is the promise it holds for deciphering other resistance genes, en route to a natural barrier to infection, at a time when the fungus has already developed tolerance to most types of fungicides.

One of them was able to cause full - blown disease symptoms — tan spore - producing lesions on the leaves — on eight soybean lines, including two with multiple resistance genes.

Others might be engineered to include nutrients like beta carotene, iron, and vitamin A. Instead of one gene to fight off insects or disease, crops will be engineered with «stacks» of resistance genes to prevent pests from evolving resistance to a single approach.

Growing resistance to malaria drugs in Southeast Asia is caused by a single mutated gene inside the disease - causing Plasmodium falciparum parasite, according to a study led by David Fidock, PhD, professor of microbiology & immunology and of medical sciences (in medicine) at Columbia University Medical Center.

It is the wild relatives of crops which contain genes for resistance to disease and pests, stock for use in grafting and characteristics to improve the properties of the crops themselves.

«Genetic link to susceptibility and resistance to inflammatory bowel disease: Overexpression of the Cd14 gene offers protection against IBD in mice, suggesting a new therapeutic approach.»

The genome also revealed the location of genes that may be involved in fighting off pathogens, which will help scientists understand more about disease resistance in pines.

Modern breeding has resuscitated grocery store tomatoes with an influx of wild genes; in the past 50 years, researchers have bred back some 40 disease - resistance genes into commercial crops.

In a report published January 22, 2018 as part of a cover story in Nature Genetics, the team highlights one set of valuable tools uncovered in their analysis: thousands of genes that appear to encode disease resistance.

Members of a family that includes the apoptosis regulator APAF1 (apoptotic - protease - activating factor 1), mammalian NOD - LRR proteins (also known as NACHT - LRR proteins or CATERPILLERs) and plant disease - resistance gene products.

«This means disease - causing bacteria in chickens are at risk of sickening humans and transferring their resistance genes in the process.

The most famous one is the gene that causes sickle cell anemia: While two copies of that gene cause a disease that's devastating in its own right, a single copy creates a healthy child with strong malarial resistance.

Extremely precise genome - editing techniques such as CRISPR / Cas9 now make it possible to adjust the genes of endangered species toward better resistance to exotic diseases, or to modify the genes of invasive species to reduce their ability to reproduce.

A gene involved in the process of resistance to a disease or pathogen; especially a gene involved in the process of antibiotic resistance in a bacterium or other pathogenic microorganism.

resistance gene A gene involved in the process of resistance to a disease or pathogen; especially a gene involved in the process of antibiotic resistance in a bacterium or other pathogenic microorganism.

Conclusions We present an accurate and comprehensive annotation of the oil palm genome, focusing on analysis of important categories of genes (GC3 - rich and intronless), as well as those associated with important functions, such as FA biosynthesis and disease resistance.

Classification and characterization of genes associated with traits of interest, such as those for fatty acid biosynthesis and disease resistance, were also limited.

This paper presents the characterization of the oil palm genome using different gene prediction methods and comparative genomics analysis, identification of FA biosynthesis and disease resistance genes, and the development of an annotation database and bioinformatics tools.

This project will discover genes that control cuticle development and function in corn, evaluate the potential for improvement of the leaf cuticle to help produce crops with increased drought tolerance and resistance to diseases, and generate tools to guide these efforts.

High humidity suppresses ssi4 - mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

«Our study demonstrates that even well - studied bacteria — the ones that we know cause disease or their close relatives — have many genes associated with antibiotic resistance that have not been characterized before,» said senior author Gautam Dantas, PhD, associate professor of pathology and immunology.

The advent of rice varieties bearing genes with resistance to the disease has changed the perception about the disease: the incorporation of host - plant resistance genes in rice varieties, their adoption and deployment in the world's main rice - producing environments is probably one of the most significant evidences of the role of plant pathology in agricultural development.

One use of these genes might be to insert them into other crop plants to provide «disease resistance, or to make them grow bigger and faster,» says Kaul.

The utility of the gene has not been fully determined but in the future researchers hope to clone the gene and transfer disease resistance to other wheat varieties.

They use natural plant centromeres (a key part of chromosomes needed for their inheritance), promoters (gene activation sites), and gene - termination sequences to assemble linear or circular minichromosomes that contain at least a dozen genes that can improve crops by promoting traits like pest and disease resistance.

At the outset of the game, players are informed of how the science poses numerous medical benefits when Dr. Naomi Hunter explains: «we can remove genes which we know may lead to sickness or disease, and at the same time, splice in genes with beneficial effects such as resistance to cancer.»