Sentences with phrase «of disease stage»

Expression of RANKL / RANK / OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation.

Regardless of disease stage, patients who received surgery lived an average of 57 months, compared to less than 12 months for patients who received only non-surgical treatment (such as chemotherapy or radiation therapy), and 1.4 months for patients who received no treatment at all.

Not exact matches

Darzalex, however, has not yet reached its peak potential as the drug moves into earlier stages of the disease and is being tested on solid tumours like lung cancer.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

Acceleron is a Cambridge - based, clinical - stage biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics to treat serious and rare diseases.

While the pill is still in its experimental stage — the company has said it could take up to 10 years for the pill to be prescribed, the AP reports — this technology has the potential to dramatically transform the way we diagnose and treat a host of diseases, most notably cancer.

A handful of Biotech companies, including SynCardia, Carmat and AbioCor are in various stages of developing a truly permanent mechanical heart that could replace a patient's diseased heart and carry them through the rest of their lifetime, the Verge reports.

Solanezumab, a drug developed by Eli Lilly that also acts on the amyloid hypothesis, failed some key clinical trials, though the company is still testing it in the pre-clinical stages of the disease.

In a late - stage trial, Darzalex combined with Velcade and chemotherapy slashed patients» risk of worsening disease or death by a stunning 61 % compared with the results for Velcade and chemotherapy alone.

Fernando Pagan, a GUMC associate professor of neurology who directs the Movement Disorders Program at MedStar Georgetown University Hospital, said that to his knowledge, the study «represents the first time a therapy appears to reverse — to a greater or lesser degree depending on stage of disease — cognitive and motor decline in patients with these neurodegenerative disorders.»

CalciMedica is a privately - held, clinical stage biopharmaceutical company focused on CRAC channel drug discovery and development for the treatment of acute and chronic inflammatory diseases.

At the Challenge Festival, startups like as BaseTrace, which «uses DNA - based tracers to track where industrial fluids are going in large, complex environments» and Reliefwatch, a cloud - based system that uses smartphone technology to track inventory and diseases for healthcare organizations in the developing world, battled it out on stage for a grand prize of $ 150,000 in investment.

«The real opportunity for artificial intelligence,» he said, is detecting signs of disease sooner in the many people who «go from stage one to stage two to stage three cancer» before it's caught by a doctor.

Years ago, when Mass Design was in the early stages of planning and designing Butaro Hospital in the Burera District of Rwanda, it faced a serious design challenge: To reduce the transmission of airborne diseases like TB.

Belvin, who in 2004 was a 22 - year - old grad student in New Jersey, was diagnosed with Stage 4 melanoma, a disease that then typically killed five out of six patients within five years.

It would also set the stage for the next items on the list of diseases it hopes eventually to wipe out, starting with malaria.

The company is also seeking deeper inroads into rare diseases, with a number of assets in late - stage development, and last year it scored a major regulatory win when Europe approved its «bubble boy syndrome» gene therapy Strimvelis.

Gain Therapeutics (www.gaintherapeutics.com) is a preclinical stage biotech company developing a class of next generation pharmacological chaperones for the treatment of devastating rare diseases using the SEE - Tx technology.

Minoryx is a clinical stage biotech company leading the development of new therapies for X-linked Adrenoleukodystrophy (X-ALD) and other inborn errors of metabolism, a group of rare diseases of genetic origin with a high unmet medical need.

Our goal is to complement the current strategic interest of Chiesi Farmaceutici in the space of rare diseases by investing in early stage opportunities and accelerate the expansion of the Chiesi network in the US among universities, venture capital investors, rare disease patient organizations and start - ups developing treatments for rare diseases.

BioNTech hit the headlines in July when its experimental personalized cancer vaccine, tailored to the tumors of individual patients, kept disease in check in an early - stage clinical trial.

The technology measures the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity in several cancers and Alzheimer's disease.

Alnylam, which has been weighed down in the past by drug safety concerns, said it plans to initiate a program targeting cardiomyopathy - another symptom of the disease - alongside polyneuropathy in a late - stage study next year.

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

Although Anavex Life Sciences» Alzheimer's disease program should offer up plenty of data to digest this year, its research program is very early stage, and the company's balance sheet is worrisome enough for me to avoid it until placebo - controlled trial results are available.

The detection of melanoma at its most curable stages can result in decades of high - quality life saved, versus the treatment of this terrible disease at late stages, which offers several months of life extension, at best.»

A married retired man who finds his wife sexually unattractive tracks down a college girlfriend, a widow in the early stages of Alzheimer's disease, and the two begin a passionate affair.

They're in the final stages of the heart disease called individualism Tocqueville describes.

A newborn is not fully sentient, nor is a person in an advanced stage of Alzheimer's disease.

They raise the question of whether aging is best understood as a natural, permanent stage of life or a disease.

The Human Genome Project, not long ago completed at a cost of $ 3 billion, was often presented by its promoters as opening the way to discovering the ultimate genetic causes of all diseases, thus setting the stage for their cure.

We could have TV spots featuring someone like Rock Hudson at a stage of the AIDS disease where its ravages are unmistakable.

Leprosy, a skin disease, during the last stages of which members of the body rot away, was considered a communicable disease in ancient society.

The beginning stage of gum disease is called gingivitis.

If you carry the genes, you have a 1 in 30 chance of developing coeliac disease at some stage in your life.

Radiologists came from across the hospital to peer at the results, disbelieving: A perfectly healthy 21 - year - old nonsmoker with no family history of the disease had lung cancer, which three days later would be diagnosed as stage IV, the most advanced form.

Gyan, who enjoyed a successful stint at the Stadium of Light but is best known for his exploits at the 2010 World Cup, was set to lead his team out for the crucial group stage clash, but is likely to sit this one despite having been released from hospital after just one night because the disease was caught so early.

The disease was deemed to be in its later stages by a Lyme disease specialist when it was diagnosed, who then recommended a treatment program of intensive antibiotic therapy for several months.

«I'm sorry, but f**k cancer,» Kerr said in France after winning the contest staged in memory of LET player Cassandra Kirkland, who died earlier this year at age 32 from lung cancer, and just days after former LPGA Tour golfer Kelli Kuehne's mother passed away from the disease.

I worry that lost amidst the hoopla about the new CTE study is the fact that not every football player whose brain was donated to the CTE Center for pathological scrutiny was found to have the disease, and, that it was not detected in either the brains donated by the families of football players who died before they got to high school, and in only three of fourteen of high school players (and, in those, the disease had not progressed beyond the «mild» stage).

Cervical cancer is a disease that evolves slowly over the course of a decade or more and has clearly recognizable pre-cancerous stages.

In the beginning stages, when all there in your breasts is colostrum, your baby receives the benefit of protection from diseases and immunities that can't be given any other way.

Role of Breastfeeding Cessation in Mediating the Relationship between Maternal HIV Disease Stage and Increased Child Mortality among HIV - Exposed Uninfected Children Author (s): Fox MP, Brooks DR, et al., Published: 2009 Summary: This study, published in the International Journal of Epidemiology, analyzed the role of breastfeeding cessation and its effect on mortality of HIV - exposed children.

Role of Breastfeeding Cessation in Mediating the Relationship between Maternal HIV Disease Stage and Increased Child Mortality among HIV - Exposed Uninfected Children

The wife of ailing former Assembly Speaker Mel Miller has launched a desperate campaign to find him an organ donor, saying he is suffering from end stage kidney disease and needs a transplant to save his life.

By the time Artvoice published last week the comments Paladino made in a year end survey — saying he wished death by mad cow disease upon President Barack Obama and wanted First Lady Michelle Obama to be «let loose in the outback of Zimbabwe where she lives comfortably in a cave with Maxie, the gorilla» — the developer was already on a national stage poised for scrutiny from some of the country's largest media outlets, including The New York Times, Washington Post and CNN.

The deadly Ebola Virus Disease, which raged in some African countries including Nigeria in 2014, has staged a return in northwestern part of the Democratic Republic...

Lansley echoed calls from BBC presenter George Alagiah, who has stage 4 bowel cancer, to reduce the age of NHS screening for the disease to 50.

«But we have to be honest and say that, based on all the evidence, including data presented by the drug companies themselves, our experts have concluded that these drugs do not make enough of a difference for us to recommend their use for treating all stages of Alzheimer's disease.

The institute instead ruled that donepezil, rivastigmine and galantamine would only be made available to people at the moderate stage of the disease, saying the medicine did «not make enough of a difference» for some patients.