Sentences with phrase «of dogs with the mutation»

Breeding of dogs with the mutation could be conducted as described above.

When that information is known we'll have a better idea what percentage of the dogs with the mutation will ultimately develop HC.

It is very possible, given the disparity between the numbers of dogs with the mutation and the frequency of cataracts that HSF4 positive / no cataracts families might be possible, but without further study we can not be sure.

Over time, the number of clear dogs available will increase and use of dogs with the mutation can be phased out.

Normal / Normal littermates of dogs with the mutation, if of equal quality, should be given preference for breeding.

Not exact matches

The new CNGB1 mutation in Phalenes and Papillons was discovered with six cases and 14 control dogs and confirmed in a larger cohort of dogs.

The researchers began their study by looking at dogs of one breed, the Portuguese water dog, and found that those with one type of mutation of IGF1 were 15 to 20 percent smaller.

Researchers used it, in conjunction with the complete genomes of several modern dogs and wolves, to calculate a genetic mutation rate for canines.

Given that certain wolves carry the «friendly» mutations, the study suggests the domestication of dogs began with friendlier individual wolves.

An international team of scientists, led by researchers at the German Leibniz Institute for Zoo and Wildlife Research (IZW), conducted genetic analyses of CDV strains obtained from a range of carnivores between 1993 and 2012 and discovered that lethal CDV infections in lions and hyenas during the 1993/1994 epidemic was caused by a rare and genetically distinct CDV strain with three rare mutations not present in any other Serengeti strain isolated from domestic dogs or wild canids.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson's and muscular dystrophy.

The dog will display symptoms associated with the disorder and will always pass on a copy of the mutation to any offspring.

This regulatory activity is genetically determined and if mutations occur in the gene or genes responsible it results in the build up of copper and a toxicosis which can occur in people with Wilson's disease and in some breeds of dogs, principally Bedlington terriers.

In the meantime, we have become aware that more non-COMMD1 (i.e. dogs which are 1:1 with no copies of the COMMD1 deletion mutations or 1:2 with only one copy of the COMMD1 deletion) Bedlington terriers in the UK are being reported by their vets or breed societies with clear symptoms indicating CT..

Dogs with mutations in the MDR1 gene can exhibit sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications.

The VCGL laboratory has just released a test for the genetic mutation associated with the development of arrhythmogenic right ventricular cardiomyopathy in boxer dogs.

Female dogs with one copy of the GRMD mutation are carriers.

After examining over 300 dogs, Dr. Stern identified a mutation in the phosphatidylinositol - binding clathrin assembly protein (PICALM), a protein that is found in the canine heart, that is associated with the development of SAS in Newfoundland dogs and determined that this particular mutation is passed down to their puppies.

Male dogs with one copy of the mutation are affected.

Washington State U. Vet School says, re ivermectin: «While the dose of ivermectin used to prevent heartworm infection (6 micrograms per kilogram) is safe in dogs with the [MDR1] mutation, higher doses such as those used for treating mange (300 - 600 micrograms per kilogram)[are not].»

Dogs with one copy of the mutation are carriers.

A dog with posterior punctate cataracts might be in the early stages of hereditary disease and should have the DNA test for the HSF4 cataract mutation.

The mode of inheritance for most Aussie cataracts is dominant with incomplete penetrance, meaning not every dog with the mutation will develop cataracts though 70 % of those with cataracts have it.

Dogs that carry both mutations are at the highest risk of getting sick from the disease, although dogs with a mutation in either gene can develop the disease as wDogs that carry both mutations are at the highest risk of getting sick from the disease, although dogs with a mutation in either gene can develop the disease as wdogs with a mutation in either gene can develop the disease as well.

ref 1 Genetic mutations are occurring at an unprecedented rate but over-use of vaccines must share equal blame with the x-ray fad that compels eager - to - conform dog breeders.

Dogs with two copies of the mutation are affected, dogs with one copy are carriDogs with two copies of the mutation are affected, dogs with one copy are carridogs with one copy are carriers.

Dogs with one or two copies of the mutation have a heightened risk for developing cataracts.

Two copies of the mutation mean the dog is affected with CMR; dogs with one copy are carriers.

In collaboration with the Drentsche Patrijshond Club of North America, the Spokane - based company studied 13 Drents for 142 different mutations known to occur in domestic dogs.

Breed carriers (parents of affected dogs or those with one mutation) only to clear - tested mates.

A dog which has one copy of the gene with the mutation and one copy without the mutation.

They found that dogs with two copies of the mutation are at the greatest risk.

Some of the mutations were in genes involved with brain development, which the researchers interpreted as relating to the less aggressive temperaments of dogs compared to wolves.

«We've found something in about a quarter of pet Labradors that fits with a hardwired biological reason for the food - obsessed behavior reported by owners... There are plenty of food - motivated dogs in the cohort who don't have the mutation, but there's still quite a striking effect,» Raffan says of the study's findings.

Cyclic Hematopoiesis with color dilution AP3B1 ELANE mutation causing cycles of low wbc (white blood cell production) in collies predispose these dogs to secondary bacterial infections and amyloidosis, and most die less then one year of age.

«This detection will help avoid breeding boxer dogs with the mutation,» says Bryan Slinker, DVM, Ph.D., dean of WSU's College of Veterinary Medicine.

A study by UC Davis showed that there was a prevalence of genetic disorders in both populations (rescue and bred): «Recently derived breeds or those from similar lineages appeared to be more susceptible to certain disorders that affect all closely related purebred dogs, whereas disorders with equal prevalence in the two populations suggested that those disorders represented more ancient mutations that are widely spread through the dog population.»

Dogs with mutations in both copies of the SLC2A9 gene are predisposed to have elevated levels of uric acid in the urine, hence the name hyperuricosuria.

The dog will display symptoms associated with the disorder and will always pass a copy of the mutation to its offspring.

There is complete concordance of the mutation with the disease among affected dogs in the Mastiffs, Great Pyrenees, Australian Shepherds, Coton de Tulear and Lapponian Herders.

So, one of the mysteries of Doberman vWD that has puzzled scientists for years, how affected dogs can end up with a small amount of completely normal vWf, is cleared up by understanding this type of mutation.

Example: Immodium (Loperamide) can be neurotoxoic is some collies and other breeds with MDR1 mutation, using peroxide to induce vomiting is contraindicated in some cases as some things dogs ingest should NOT be vomited up, and peroxide may cause gastritis if over-used (using it 3x as suggested here is a bad idea, and ideally should not be used at all w / o first talking to a vet or a toxicology hotline with knowledge about dogs, peroxide not a good idea at all for cats and 10 mls is NOT a standard dose for every dog!!!!), mineral oil can cause aspiration pneumonia if it gets in the lungs and I would not recommend it to most pet owners to administer, and pepto bismol products sometimes contain xylitol which is deadly, aspirin is OK in a pinch but can cause serious problems with long term use... that's just a few thoughts off the top of my head.

Testing / Breeding recommendations: It is recommended to test dogs for the presence of the KRT71 mutation prior to breeding to avoid producing progeny with an undesired coat type.

The severity of the reaction depends on whether the dog inherits one or two copies of the mutation, and the breeds most commonly found with the mutations include herding dogs, such as collies and Australian shepherds.

It is important to never breed two dogs together that carry one or more copies of the mutation, in order to avoid producing offspring that are affected with BFJE.

The mode of inheritance has not been determined precisely but the fact that dogs heterozygous for the KRT71 mutation do not have curls and also the occasional occurrence of dogs with curly hair in breeds with typically straight hair suggests that the curly hair is inherited in a recessive or incompletely dominant mode.

When the RSPO2 mutation and the mutation associated with the curly hair trait segregate in a breed, as they do in the Portuguese Water Dog, a variety of coat types can be expected in the progeny: tight curls with furnishings, wavy coats without furnishings and flat coats with no obvious curls or waves.

A mutation for Curly Hair: A genetic study of coat type in purebred dogs has identified a mutation in the keratin gene, KRT71, associated with the curly hair phenotype in some breeds (1).

Normal kidneys reabsorb the Amino Acid cystine so that only small amounts pass into the urine, while dogs with mutations of both copies of the SLC3A1 gene fail to reabsorb cystine allowing large amounts to pass into the urine, hence the name cystinuria.

There is variability in the amount of vWf such that not all dogs with two copies of the Mutation are equally affected.