V. Lo Sardo et al., «Influence
of donor age on induced pluripotent stem cells,» Nature Biotechnology, doi: 10.1038 / nbt.3749, 2016.
Not exact matches
Mike Kope, CEO at SENS, said
of Buterin's charity, «SENS Research Foundation is honored to be the recipient
of Vitalik's incredible generosity... His support is critical to SENS Research Foundation's expansion
of our programs... Our work to cure the diseases
of aging is dependent on the generous support
of our
donors and we appreciate his support tremendously.»
The
donor serves as the custodian
of the gift until the minor reaches the legal
age of majority (this varies from state to state, but is typically 18 or 21).
The charity serves as a platform through which individual
donors can support the education, health care, job training and personal development
of young people from birth to 24 years
of age.
by Lori Gottlieb — a single mother who conceived her only child with
donor sperm rather than miss out on motherhood as she has on marriage — is a frank and excruciatingly personal look into some
of the sexual revolution's lonelier venues, including the creation
of children by anonymous or absent sperm
donors, the utter corrosiveness
of taking a consumerist approach to romance, and the miserable effects
of advancing
age on one's sexual marketability.
Open sperm donation is really called open identity, which means that you have access to the
donor or information about the
donor once you reach the
age of 18.
He received
donor milk and formula for about 4 weeks, at six months
of age, because I was hospitalized for Crohn's Disease.
Infant formula is suitable for use from birth to 12 months
of age when babies are not breastfed or receiving expressed or
donor breastmilk.
Egg
donors are young, healthy women between the
ages of 21 and 29 who live across the United States.
At the time milk is expressed, the
donor must have a child under the
age of one year.
To participate in our egg
donor program and receive egg
donor compensation, you must be between the
ages of 21 and 31 and have a body mass index, or BMI,
of less than 27.
All
of our anonymous egg
donors are 21 - 31 years old, an
age when eggs are at their healthiest and most viable.
«She demonstrated that, even in this day and
age, a candidate with a real message doesn't necessarily need the support
of the party apparatus, or the financial backing
of big
donors, to have an impact.»
[73] On November 4, 2009, George Stephanopoulos, host
of ABC News This Week, claimed «Pataki has told at least one major GOP
donor in private that he is not interested in becoming a senator at the
age of 64 and would rather run for president in 2012».
By enacting legislation that lowers that
age of donors, New York is following the example
of 47 other states in opens the state organ
donor registry to younger adults in the hopes
of increasing enrollment rates.
Regulatory requirements on the maximum
age of sperm
donors tend to range between 40 and 45 years.
Our study shows that we are good at selecting the right sperm
donors with the right sperm quality — and that's why we found no difference in live birth rate despite the increasing
age of sperm
donors.
Indeed, this trend
of less likelihood
of live birth with younger sperm
donor age might simply be explained by the fact that younger men who donate sperm are less likely to have proven fertility themselves than older sperm
donors with proven fertility.»
«Our results suggest that, up to the
age of 45, there is little effect
of male
age on treatment outcome, but sperm
donors are a selected population based on good sperm quality.
«The outcome
of fertility treatments using
donor sperm is not dependent on male
age, but on the quality
of sperm.»
However, within these same two female
age bands, no significant differences were found in live birth rate (LBR) relative to the
age of sperm
donor.
* in the older IVF patients LBR was 11 % with a
donor under the
age of 20, 17 % with
donor aged 26 - 30, and 16.6 % with a
donor aged 41 - 45
There was a trend, for example, that sperm
donors under the
age of 20 were associated with a less successful outcome than older
donors.
With the assumption that female fertility clearly declines with
age, the study divided its female subjects into two groups: those who were treated with
donor sperm between the
ages of 18 and 34, and those who were treated after the
age of 37.
Despite emerging evidence
of a decline in sperm quality with increasing
age, an analysis
of every first fertility treatment cycle performed in the UK using sperm donation shows that outcome in terms
of live birth is not affected by the
age of the sperm
donor.
The team also tested nanoparticle absorption for other kinds
of human cells, including fibroblasts from
donors of older
ages and found significant differences.
Although teens are often able to register as organ
donors when they get a driver's license, just 24 percent
of parents
of teens
ages 15 - 18 said their child had registered.
To run his study, Maharaj plans to recruit
donors between the
ages of 18 and 35 and inject them with G - CSF and collect their plasma.
«The use
of DCD
donors over the
age of 60 is highly controversial, but we showed that excellent results could be expected if the cold ischaemic time is limited to less than 6 hours,» said Dr Detry.
«As the population
of Western countries is
aging, we will have to consider older
donors even more often in the future,» said Dr Detry.
A total
of 70 DCD liver transplants were performed at the investigators» institution: 32 from
donors aged 55 years and younger, 20 from
donors between 56 and 69 years, and 18 from
donors aged 70 years and older.
In addition, uncovering the
age of existing
donors may be difficult.
«We studied human T cells, isolated from blood
donors of all
ages, to compare mature cytotoxic T cells with naive ones,» said Philip Ansumana Hull, graduate student in Ott's lab and one
of the first authors
of the study.
This method involves removing the freshly fertilized nucleus from an egg that has little chance
of further development because
of age or disease and injecting it into the
donor egg.
Studies also show that egg donation is an increasingly successful treatment, with live birth rates
of around 55 % per transfer recorded in the latest US data; success largely depends on the
age of the
donor, not on the
age of the recipient.
In addition, recipients
of red blood cells from
donors aged 20 - 30 were associated with a six percent increased risk
of death per transfused product compared with recipients
of red blood cells from
donors aged 40 - 50.
Recipients
of blood from
donors aged 17 - 20 were associated with an eight percent increased risk
of death per unit transfused compared with recipients
of red blood cells from
donors aged 40 - 50.
Wanting to learn more about how the brain copes with
donor hands, cognitive neuroscientist Angela Sirigu
of the French National Research Agency in Lyon and colleagues looked at two right - handed men, one
age 20 and the other 42, who recently had left and right hand transplants to replace hands amputated following work injuries 3 to 4 years ago.
Consent rates were highest among potential
donors under the
age of 55, patients
of white race, and when the referral from the local hospital was made in a «timely» manner.
The researchers note that these data alone do not capture all potential deceased organ
donors in the U.S., as the current definition
of an eligible death excludes potential
donors over
age 70, and those classified as a «donation after cardiac death»
donor, both
of which broaden the pool
of available
donors.
They also would not identify the
donor or the date
of the transplant, saying only that it had occurred sometime in the past two weeks and that the recipient and
donor were the same gender and race and roughly the same
age.
Researchers think this process may not completely reprogram the adult
donor's DNA to resemble that
of a fresh embryo; if that's true, cloned animals might
age faster than normal animals, in essence starting out at the
age of the
donor.
However, the experiences described in this commentary show that individuals
of all
ages may unintentionally discover that they were
donor - conceived if they or their family members take DNA tests for unrelated reasons.
Inhibition
of cell division is also more pronounced with
donor age [8].
Would her cells show the
age of the
donor or
of a newborn?
Bone Marrow Transplant: (back to top)
Donor Mice: To isolate bone marrow, donor mice (female, 6 - 12 weeks of age) will be euthanized, and femurs will be dissected free of tissue and flushed with
Donor Mice: To isolate bone marrow,
donor mice (female, 6 - 12 weeks of age) will be euthanized, and femurs will be dissected free of tissue and flushed with
donor mice (female, 6 - 12 weeks
of age) will be euthanized, and femurs will be dissected free
of tissue and flushed with PBS.
Three human cornea pairs (
donor ages 30 - 37 years), stored in Optisol, were labeled by chemifluorescence to show incorporation
of BrdU into new DNA using a commercial procedure (Hoffman - La Roche, Nutley NJ) as based on the work
of Elwart and Dormer [21].
Mehta J, Gordon LI, Tallman MS, et al., Does younger
donor age affect the outcome
of reduced - intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies beneficially?
We endeavored to test both central - intermediate and peripheral activity in a
donor sample
of mixed
ages (21 - 52 years) as shown in Figure 2F.
To find out, the researchers examined methylation patterns in iPSCs derived from the peripheral blood mononuclear cells
of 16
donors,
ages 21 to 100.