Sentences with phrase «of donor cells»

This approach also does not rely on the identification of a matched donor, thus avoiding the risk of rejection of donor cells.

After all that time, nearly 90 percent of the donor cells remained healthy and fully functioning, an unprecedented amount.

The presence of large numbers of donor cells in recipients has long been observed in bone marrow transplantation, a discipline Starzl believes has advanced basic science more than organ transplantation has to date.

A small number of donor cells in both the intraretinal and subretinal locations were immunopositive for proliferating cell nuclear antigen (PCNA)(Figure 5C and D), even in the oldest rats examined (P150).

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

(F) High power view of box f from panel E showing rescued ONL and the underlying, semi-continuous layer of donor cells between the photoreceptors and RPE (arrow).

A long - standing question has been how to improve the success of BMT by reducing GVHD incidence while, at the same time, preserving the anti-tumor response of donor cells.

«The unique aspect of our procedure, which no one else in the world is doing, is the formation of blisters as the source of donor cells combined with laser surgery to prepare the grafted areas.

Each patient then received a kidney from a genetically mismatched relative or unrelated donor; the concoction of donor cells processed by Ildstad's team was given a day later.

Note the location of donor cell nuclei in both the inner retina and subretinal space.

Procedures include purging of cancerous cells and purifying donor stem cells to minimize graft - versus - host disease (a serious side effect related to the use of donor cells for transplant).

There is a pigmented RPE - like (RPE - L) layer of donor cells above the host RPE layer, whereas donor cells in the inner retina do not have pigment granules (right - pointing arrows).

However, the morphology of the host inner retinal cells was well - preserved in the area of donor cell migration, as evident from the PKCα antibody staining, which labeled normal - appearing rod bipolar cell dendrites (upward arrows in Figure 6B).

We have a long - standing interest in detection of small numbers of donor cells within a recipient (known as microchimerism).

Examples include a series of studies to document persistent microchimerism of donor cells in transfusion recipients, with particular focus on mechanisms and clinical relevance of donor stem cell microchimerism in transfused trauma patients, and the immunological mechanisms and prevention of transfusion - related acute lung injury (TRALI) and alloimmunization.

Despite the observed decline of HPC - derived cells in peripheral blood, 1 — 3 % of bone marrow cells were ES - derived past 100 days, suggesting long - term persistence of donor cells.

At day 100 post-transplantation, the percentage of donor cells had decreased (D).

Once long - term mixed chimerism was established, we determined the influence of donor cells on the ability of the host's T cells to respond to alloantigen.

Cloning relies on a process known as somatic cell nuclear transfer, in which the nucleus of a donor cell is transferred into a fertilized egg that has been emptied of its chromosomes.

These organs could be made viable by stripping them of donor cells, then recoating them with a patient's own.