Sentences with phrase «of dopaminergic neurons»

We also observe a significant loss of dopaminergic neurons in the substantia nigra pars compacta 60 days after infection.

It is a motor disorder caused by the loss of dopaminergic neurons in the black substance of the brain.

The combining of the VEGF and GDNF not only significantly reduced the degeneration of the dopaminergic neurons of the black substance, it also induced the formation of new cells and cellular differentiation.

Functional rescue of dopaminergic neuron loss in Parkinson's disease mice after transplantation of hematopoietic stem and progenitor cells, EBioMedicine, in press.

First, we counted the number of dopaminergic neurons in the SNpc using unbiased stereology.

«Parkinson's: Small molecules researched for the regeneration of dopaminergic neurons.»

We would like to test the activity of the the latter molecule towards survival of dopaminergic neurons and test both GDNF mimetics in animal model of PD.»

«The impairment is correlated with the specific anatomic distribution of the dopaminergic neurons and their terminals,» pointed out the researcher Catalina Requejo.

«The takeaway here is that even relatively late in the disease, when 60 - 80 percent of dopaminergic neurons have died, there is still an opportunity to promote plasticity in the brain,» Prof. Hausdorff concludes.

One even showed greater dopamine activity in the injured side of the brain than on the normal side, indicating, says Jaenisch, that «these IPS cells could be used also for generating function of dopaminergic neurons that could have therapeutic value.»

40: Hallett PJ, Cooper O, Sadi D, Robertson H, Mendez I, Isacson O. Long - term health of dopaminergic neuron transplants in Parkinson's disease patients.

Despite his considerable teaching load, Hoffmann remained active in the laboratory, publishing more than 50 journal articles, primarily on the development and aggregation of dopaminergic neurons and the neurotoxicity of amphetamines.

Stereological counts of dopaminergic neurons in the SNpc.

Our results support our primary goal of identifying a previously approved drug that may allow us to deplete mitotic NSCs from an otherwise differentiated population of dopaminergic neurons, thus ensuring their safety for use in transplantation.

Previously we described the anatomy of the adult MB and defined 20 types of dopaminergic neurons (DANs) that each innervate distinct MB compartments (Aso et al., 2014a; Aso et al., 2014b).

Parkinson's disease is a progressive neurodegenerative disorder mainly characterized by the loss of dopaminergic neurons from the substantia nigra pars compacta and the presence, in the affected brain regions, of protein inclusions called «Lewy bodies».

These results from Menegas et al. show that the outputs of dopaminergic neurons are more distinctive then their inputs.

Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease.

Functional rescue of dopaminergic neuron loss in Parkinson's disease mice after transplantation of hematopoietic stem and progenitor cells.

The main finding in brains of people with PD is loss of dopaminergic neurons in the area of the brain known as the substantia nigra.

Here we show that the loss of dopaminergic neurons can be protected against by direct actions in the substantia nigra.

The disease is caused by a loss of dopaminergic neurons in the brain, which leads to a progressive loss of muscle control, increased disability, and cognitive and psychological challenges.