Sentences with phrase «of drug discovery research»
He believes that a great deal of drug discovery research, and hence informal training in the area, is performed at academic institutions located in Canada's bioscience clusters, and their spin - off companies.
http://www.sciencemag.org/ Not exact matches
In January 2017, SiteOne announced the closing of a research and development agreement with Amgen, a collaboration focused on combining SiteOne's experienced drug discovery team and portfolio of novel Naᵥ1.7 inhibitors with Amgen's neuroscience capabilities.
«Her breadth of experience in biomedical research and development can benefit Exelixis greatly as the company recommits its resources to drug discovery and bolstering its pipeline following the successful ongoing commercialization of its lead medicine, CABOMETYX.»
An original co-founder of MaRS, U of T has chosen the site for its renowned research teams working in drug discovery, regenerative medicine, infectious diseases and advanced computing.
SOUTH SAN FRANCISCO, Calif. — February 5, 2018 — FLX Bio, Inc., a biopharmaceutical company focused on the discovery and development of oral small molecule drugs to activate the immune system against cancer, today announced the appointment of senior pharmaceutical research and development executive Michael F. Giordano, M.D., to its Board of Directors.
As an investment, a drug that is in the discovery or pre-clinical stage is a very risky proposition, with less than a 1 % chance of getting to market (according to an industry report published in 2003 by the Pharmaceutical Research and Manufacturers of America).
MaRS Innovation (MI) and the Centre for Drug Research and Development (CDRD) are pleased to announce that they have entered into an agreement to collaborate on projects of mutual interest with a goal to advance and commercialize early - stage health - related discoveries.
This includes a stem cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will use donated cells from people with Alzheimer's to test potential new treatments
Looking at sixty - seven recent drug discovery projects based on preclinical cancer biology research, they found that in more than 75 percent of cases the published data did not match up with their in - house attempts to replicate.
In listening to our terminally ill patients, we were always impressed that even the most accepting, the most realistic patients left the possibility open for some cure, for the discovery of a new drug or the «last minute success in a research project.»
PDX models are created by implanting cancerous tissue from a human primary tumor directly into immunodeficient mouse or rat models, enabling acceleration of oncology research or drug discovery and development programs.
Although the pharmaceutical industry, like the rest of the business world, has suffered a slowdown, the market research company Frost and Sullivan still expects spending on drug discovery to expand from US$ 19.6 billion in 2002 to US$ 25.6 billion by 2006, an annual growth rate of about 6 %.
Experts say it could also help to boost supplies of cells for use in drug discovery research and could eventually aid production of cells for use as therapies.
Of approximately 300 staff at the Center for Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and deveResearch, only nine postdocs and students are conducting basic research; the rest work in drug discovery and deveresearch; the rest work in drug discovery and development.
Making the Leap: When, How, and Why a Career in Drug Discovery May Be Right for You Matthew Bell who heads of discovery research for Wyeth Pharmaceuticals tells when, how, and why a career in drug discovery may be right for Drug Discovery May Be Right for You Matthew Bell who heads of discovery research for Wyeth Pharmaceuticals tells when, how, and why a career in drug discovery may be right for drug discovery may be right for you.
Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»
«In any CNS drug discovery program,» Hargreaves says, «occupancy studies form a very early part of research.
During one - third of the year, the students will learn about the cutting - edge developments in the life sciences with the greatest entrepreneurial potential — from bioinformatics to neuroscience, epidemiology, drug discovery, and stem cell research.
Other research groups are also generating promising results through the use of drugs to convert white fat cells into brown fat and through discoveries of the pathways and hormones that control brown fat metabolism.
The journal provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that provide new information about therapies or disease, and innovative reports of drug discovery and development.
«Anticonvulsant effects of valproic acid uncovered: Research reveals new underlying factor of seizures; points to new drug discovery approach.»
Promega, headquartered in Madison, Wisconsin, has nearly a thousand employees worldwide and manufactures over two thousand products, consisting of kits and reagents as well as integrated solutions for life science research and drug discovery, genetic identity, and clinical diagnostics.
«With the availability of more and more data analytics in health care, it's the right time to use data to direct the investments of drug discovery and biomedical research for the common good,» said the study's first author, Lixia Yao, PhD, assistant professor at the University of North Carolina at Charlotte.
«The scientists stand accused of emailing and downloading proprietary data about [GlaxoSmithKline] products and sending it to contacts working for the Chinese startup Renopharma, which provides contract research services for early drug discovery, according to its website.»
The Canadian drug discovery industry is still small, especially in comparison to the United States, owing to the lack of big pharmaceutical companies conducting research and development in this country.
Scientists are taking medical imaging research and drug discovery to a new level by developing a molecular imaging system that combines several advanced technologies for all - in - one imaging of both tissue models and live subjects, say presenters at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Working on the premise that scientific research is the foundation of any technology industry, Hancock and others at UBC are writing a business proposal for an integrative centre for drug research, with an objective of developing intellectual property in drug discovery, providing training for drug discovery researchers, and developing new technologies.
«These results enable future studies in Alzheimer's and other disease models and highlight the importance of basic research which precedes drug - discovery,» says Jaan - Olle Andressoo.
The discovery involved ORNL's Spallation Neutron Source, which provides the most intense pulsed neutron beams in the world for scientific research and industrial development, and ORNL's Titan supercomputer, the nation's most powerful for open science — a one - two punch for illuminating the physical properties of potential drugs that inform new design principles for safer, improved delivery platforms.
«While we celebrate the «a ha» moment of scientific discovery and invention, such moments are only the point of initiation for the basic research required to develop new drugs,» said Dr. Laura McNamee, the lead author of the paper and a research associate in Bentley's Center for Integration of Science and Industry.
«This opens up entirely new opportunities in pharmaceutical research and may lead to the discovery of new drugs,» says Yitzhak Apeloig, who specializes in organic chemistry at the Technion Israel Institute of Technology in Haifa.
Professor Elkington highlights that more research is needed to investigate the hypothesis but if it is proved, the discovery could have major implications for the design of new vaccines and drug treatments.
An essential new way to move discoveries forward has emerged in the form of multi-stakeholder collaborations involving three or more different types of organizations, such as drug companies, government regulators and patient groups, write Magdalini Papadaki, a research associate, and Gigi Hirsch, a physician - entrepreneur and executive director of the MIT Center for Biomedical Innovation.
«It will be immediately relevant to many areas of fundamental cell biology research and practical applications such as drug discovery.
Deuterium - and tritium - labeled pharmaceutical compounds are pivotal diagnostic tools in drug discovery research, providing vital information about the biological fate of drugs and drug metabolites.
The scientists stand accused of emailing and downloading proprietary data about GSK products and sending it to contacts working for the Chinese startup Renopharma, which provides contract research services for early drug discovery, according to its website.
The molecular details of our discovery will facilitate the design of new drugs and new vaccines,» said Alexis Kaushansky, PhD, an assistant professor at the Center for Infectious Disease Research.
Some basic research findings are being translated into new treatments, and with the discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.
While discovery - type positions tend to be filled by postdocs and graduate students, people who perform drug formulation research and contract manufacturing at places like the universities of Kentucky, Iowa, and Maryland often take permanent positions as group leaders, supervisors, or technicians, Mayer adds.
The pharmaceutical industry is research and development driven, given that company growth and viability are dependent on the discovery of new drug molecules.
One of the most exciting recent advances in clinical cancer research was the discovery that this subgroup of patients respond — sometimes dramatically — to a new class of drugs targeting the MAPK pathway through which BRAF signals.
Research continues to apply this fundamental discovery to the development of innovative drugs that could inhibit the X protein» highlights Dr. Simon Fletcher, from Gilead Sciences, Inc., whose team provided the in vivo verification of the discoveries made by the University of Geneva microbiologists.
The discovery, made in research laboratories at the University of Michigan Medical School and the U.S. Food and Drug Administration, is published in the online journal PLoS Pathogens.
For the study, Ho and Kosik, leading experts in Alzheimer's research, compiled a list of 64 conceivable approaches to drug discovery, addressing a range of biological mechanisms that may be involved in the disease.
Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find — relatively quickly and cheaply — antibodies that have a desired effect on cells.
The experimental research, conducted by Griffith University's Centre for Quantum Dynamics, aims to help in the design of new molecules for materials science or drug discovery.
Systems biology provides better methods of drug discovery: research teams can measure changes in genetic activity, protein levels and cellular behavior of the immune system in response to a potential vaccine.
Overall, the upcoming involvement of academia in the drug discovery process will provide graduate students and postdocs the opportunity to gain experience and skills which are important for pharmaceutical and biotech companies whilst still engaging in hypothesis - driven academic research.
Tomorrow is the 81st birthday of Gertrude Belle Elion, a biochemist who discovered several new drugs that saved thousands of lives and whose research revolutionized drug discovery.
Their discovery might ultimately lead to an alternative treatment for jaundice, such as a new drug or supplement, says Daniel Kim, a research technician in Guelph's Department of Biomedical Sciences.