Sentences with phrase «of drugs designed»

Chemotherapy Chemotherapy is simply the administration of drugs designed to kill cancer cells, but such therapy often affects normal cells as well.

Piracetam is said to act as a nootropic, a class of drugs designed to enhance memory and boost cognitive function.

Trials of drugs designed to reduce blood pressure in people with dementia have not been successful.

Although, Hedrick and Linden target different cell types, innovations by both groups could encourage clinical tests of drugs designed to switch on a patient's immune cells by eradicating secondary lung malignancies.

Checkpoint inhibitors are a class of drugs designed to free the body's immune system to fight back against cancer.

Case in point: an experimental class of drugs designed to mimic THC, the active ingredient in marijuana.

Their new approach also reduces the potential for drug abuse and avoids the most common side effects — sedation and anxiety — of drugs designed to target the nervous system's kappa opioid receptors (KORs).

In the field of drug design, the protein K - Ras is legendary.

In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a drug designed to thwart it.

She works in the fields of drug design, evaluation of environmental pollutants and ecological genomics.

For several years LPS has been in close cooperation of drug design with a number of major players in the Polish BioTechMed industry like Adamed and OncoArendi Therapeutics.

Not exact matches

The draft guidance suggests that when apps are designed to collect information about specific patients and use it to, say, assist physicians in calculating the proper dosage of a drug, they may be subject to FDA oversight.

In particular, the complaint alleges that throughout the Class Period, defendants made materially false and / or misleading statements and / or failed to disclose that (1) the trials for GED - 0301 suffered from fatal design defects, such that GED - 0301 had failed to demonstrate meaningful clinical efficacy; (2) the growth of Otezla sales had dramatically slowed during Celgene's third fiscal quarter of 2017; and (3) the clinical and nonclinical pharmacology data in Celgene's new drug application («NDA») for Ozanimod were insufficient to permit a complete review by the FDA, which resulted in the FDA issuing a refusal to file letter to Celgene regarding the NDA.

In December, Tehrani signed a deal with GlaxoSmithKline that will allow the pharmaceutical giant to test at least four of its drug candidates on a Zymeworks - designed platform, which combines a computer simulation with a way of engineering protein molecules and allows products to be refined before they move to expensive clinical trials.

• Rani Therapeutics, a San Jose, Calif. - based developer of a pill designed to replace injectable drug delivery for patients suffering from chronic diseases, raised $ 53 million in funding.

The treatment, NKTR - 181, is designed to reduce the amount of euphoria that patients feel while taking the drug (while still relieving pain symptoms).

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Rõivas, the former Prime Minister, says Estonia is working on developing «precision medicine» that would tap into the genome data of its 1.3 million citizens in order to better diagnose illnesses, treat people, and design personalized drugs.

The system — the first time ever that a state has put itself in charge of the production and distribution of marijuana — is designed to undercut lucrative and illegal drugs trafficking.

Langer, an MIT Institute Professor with some 750 patents issued or pending worldwide, was one of the first people to apply chemical engineering methods to medical applications, pioneering the use of specially designed polymers for targeted drug delivery and tissue regeneration.

What Boger wants is to create a better way to develop drugs: through a process called structure - based design in which scientists build up a new drug, atom by atom, after determining the type of molecule that might interrupt the disease process.

At least 40 brain - enhancing drugs are under development, most of them designed to target Alzheimer's.

«It essentially gives us a periodic table,» Ron DePinho, President of MD Anderson Cancer Center says, which has provided us with both diagnostic and therapeutic value as well as helped us design clinical trials to accelerate the development of new cancer drugs,».

Late last week, the Food and Drug Administration gave its stamp of approval to the marketing of the world's first device designed to help diagnose ADHD — a disorder that plagues some 6.4 million children — by scanning a child's brain waves.

The announcement from Juul (JOO - «uhl) Labs comes one day after the Food and Drug Administration questioned the design and marketing of the company's small, sleek vaping devices.

KeyBioscience designed these drugs, which include BP - 089 and KBP - 056, to have the same broad mechanism of action as KBP - 042 but deliver different effects or potency because of changes to their engineering.

We have numerous ongoing clinical trials designed to evaluate our drugs in a variety of health conditions.

But those plans are specifically designed for small businesses and would probably be able to skirt a requirement in the Affordable Care Act that requires health plans sold directly to consumers to offer a basic set of benefits, such as prescription drugs and maternity care.

This spring, tech manufacturer Intel will lead several partner firms, including Johnson & Johnson, in testing a simulated version of a blockchain platform designed to track drugs across the supply chain.

Erin's primary responsibilities at RA Capital are to manage the design and creation of all internal and external documents and resources for the company, including competitive landscapes of drugs and medical devices for disease indications and capabilities, set brand standards, and oversee internal and external marketing efforts.

RxAdvance's services are designed to target an $ 840 billion market opportunity, comprised of this $ 370 billion drug benefit, plus $ 120 billion in specialty drug management, plus an additional $ 350 billion market in managing avoidable drug - impacted medical costs.

Pass - through pricing, low admin fee, complete transparency, granular benefit design, intelligent clinical rule configuration for optimal drug utilization, unlimited formulary tier design and superior member experience through mobile cloud are a few of the many services delivered through this agreement.

Investigators have repeatedly touted the drug as a potential lynchpin in immuno - oncology, focusing on an enzyme that suppresses the immune cells Opdivo and a whole new class of PD - 1 / L1 checkpoints are designed to unleash in an attack on cancer cells.

The drug is designed to improve the usefulness of...

Prior to that he was CEO of Molecular Simulations, Inc., a $ 100 MM supplier of software for drug design now called Accelrys (NASDAQ: ACCL).

We need to design clinical trials and outcomes in a way that captures the downsides of aging in a quantitative way» that allows targets for drug approvals by the FDA.

That cash doesn't include the money PhRMA's spending on the ongoing «Go Boldly» campaign, a series of TV, print and radio ads designed to polish the drug industry's image by reminding the public that drug companies do world - class research that brings disease cures to market to save lives.

This drug is designed to reduce the build up of a neural protein in the brain called alpha - synuclein that is associated with the disease.

Celgene's lead product, Revlimid, a drug designed to treat multiple myeloma and a few other cancer types, has been benefiting from longer duration of use, strong pricing power, and high multiple myeloma market share.

I and others of like mind criticized the drug culture and related antics as a self - indulgent distraction from the goals of racial justice and peace, and worried that the new enthusiasm for «ecological consciousness» was in fact a conservative ploy designed to turn the movement away from the cause of the poor.

The evolutionary principles of natural selection, variation, and recombination are the basis for genetic algorithms, an engineering technique that has many practical applications, including aerospace engineering, architecture, astrophysics, data mining, drug discovery and design, electrical engineering, finance, geophysics, materials engineering, military strategy, pattern recognition, robotics, scheduling, and systems engineering.

The conscience you try and drown out with alcohol, drugs, and sarcastic comments... Well it turns out that conscience of yours was designed by God to wake you up out of your foolishness.

Every since mankind has been as the Apostle described us in his epistle (Again, 2 nd Timothy 3:1 - 5; see also what Jesus said in Mark 7:20 - 23), the only thing that has «advanced «at our hands is our architecture, our technology, and our search for medicinal cures for what ails us.No one is denying that we've done tremendous good with these various advances, but we've also done awful, vicious, horrendous atrocities and brutalities as well.I've heard it quoted that out of all the centuries, millennia that we've considered ourselves «civilized», we've had only a few hundred years where something approximating peace has held sway among us.So again, I'm all world seeking to «make the world a better place», as it were; I just believe that mankind in his present moral, ethical, and spiritual configuration is capable of doing so.We can always enhance out technological prowess, improve our architechural designs, and make our drugs more powerful, but what about our hearts?

Party pills are the recreational drugs that are legal to use and specifically designed to mimic the effect of illegal drugs, methamphetamine, MDMA, and LSD.

The design and manufacture of advanced injection molding and assembly systems are a growing influence in the medical device, drug delivery, and primary pharmaceutical packaging markets.

Honored for Enhanced User Experience, this advanced packaging solution supports a number of features designed to monitor the quality of medicines shipped to patients and improve medication adherence of patients to prescribed drug therapies.

In June 2016, the Food and Drug Administration (FDA) announced draft voluntary sodium reduction targets, which were partly informed by the design of the National Salt Reduction Initiative.

Another: This was a premeditated crackdown, designed to rid all amateur sports of drug use before the»84 Olympics.

Major League Baseball's policies to prevent the use of performance - enhancing drugs seemed designed to keep anyone from ever risking the full extent of the punishments.

In a 1992 article in The North American Review entitled «The Corruption of Nobility: The Rise & Fall of Thoroughbred Racing in America,» Ferraro penned a stinging rebuke against drug abuse on the backstretch, saying, «In general, treatments designed to repair a horse's injuries and to alleviate its suffering are now often used to get the animal out onto the track to compete — to force the animal, like some punch - drunk fighter, to make just one more round.