Sentences with phrase «of early embryonic development»

In the luteal phase, progesterone differentiates the endometrial stroma, increases glandular secretions, and changes the pattern of uterine proteins to produce an environment supportive of early embryonic development.
The transcriptional program of early embryonic development is tightly regulated by a set of well - defined transcription factors that suppress premature expression of differentiation genes and sustain the pluripotent identity.
Although additional research is required to propel the embryo into the next stage - that of a live fetus - this study offers a more comprehensive understanding of early embryonic development and could help improve fertility treatments.
«New methods such the CRISPR - Cas9 system for gene editing now make it possible to carry out functional studies in other species, and this will in turn lead to decisive advances in our understanding of early embryonic development in mammals.»
«Researchers solve a mystery of early embryonic development
... A description of early embryonic development is necessary though not sufficient to an understanding of the nature and worth of an early embryo.

Not exact matches

But the great and encouraging consequence of this breakthrough is that the humanity of the unborn child, even at the earliest embryonic stage of development, is now a subject of polite conversation even in the circles that so fanatically resisted acknowledging the facts of life.
First, the authors focus on a protein, the transcription factor nanog, and assert that because it «does not block the early embryonic development of the zygote,» therefore ANT - OAR «produces a crippled embryo.»
While the entity generated by deleting or disabling early embryonic genes would produce only an unorganized collection of stem cells, it would do so after a period of what appears to be relatively normal development.
This complex society may be said to begin with conception, or with a late stage of embryonic development, or with early childhood, depending upon the purpose which determines what one takes as its defining characteristic.
The decision whether the maternal or the paternal version is shut down occurs early in embryonic development — one reason, why for long it was thought that the pattern of active alleles is nearly homogeneous in the various tissues of the organism.
The researchers discovered that both major living lineages of birds (the common neognaths and the rarer paleognaths) differ from the major lineages of non-bird reptiles (crocodiles, turtles, and lizards) and from mammals in having a unique, median gene expression zone of two different facial development genes early in embryonic development.
«This burst of genetic changes happens only during the early stages of embryonic development and then it stops,» Liu said.
Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.
They also found that embryonic growth appears to be more sensitive to temperature at earlier stages of development and to moisture at later stages.
Early in embryonic development, both mouse and human placentas rely on the same set of ancient cell - growth genes.
Facial asymmetries and minor physical anomalies begin to appear early in embryonic development, mainly the first trimester of pregnancy, and can be a sign of instability during this growth.
Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life.
«Changes in metabolites can regulate earliest stages of development: Findings may offer insights into a variety of disorders, advance embryonic stem cell research.»
This is a video of rotating view of neural precursor cell tracks obtained from the cell lineage reconstruction of early Drosophila embryonic nervous system development.
But the new research suggests that these symptoms may be a late manifestation of a disease that originates much earlier, in the first steps of embryonic development.
They hope to study APOBEC's importance in fighting off mutations early in the development of embryonic life, and in the development of the eggs and sperm that carry our genes to the next generation.
This technology was pioneered by Shinya Yamanaka, who showed that the introduction of four specific proteins that are essential during early embryonic development could be used to convert adult cells into pluripotent cells.
This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the early stages of life, during embryonic development.
Other speakers proposed that all of these traits, from hormone levels to craniofacial features, have a common root in early embryonic development.
Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.
The technique marks a major development in genetic diagnoses, which previously could not be conducted this early in embryonic development and required much larger amounts of biological material.
The researchers speculate that some cases of schizophrenia afflicting only one of a pair of identical twins could be due to mutations causing the expansion of trinucleotide repeats in the affected twin during the early embryonic development.
Early embryonic development of vertebrates is controlled by the genes and their «grammar.»
The ability of a fertilized egg to generate both embryonic and extra-embryonic tissues is referred to as «totipotency,» an ultimate stem cell state seen only during the earliest stages of embryonic development.
Very soon after fertilization, the control of embryonic development shifts from pre-existing maternal gene products to the products of genes encoded by the early embryo (or zygote).
The researchers hope that these assays will be used by many laboratories that are studying the events associated with early embryonic development and the effect of repeat length and methylation status on gene expression and differentiation.
Other potential uses of embryonic stem cells include investigation of early human development, study of genetic disease and as in vitro systems for toxicology testing.
But the researchers also put a copy of the Myd88 gene near a special «promoter» sequence of DNA that gets switched on during early embryonic development.
A second method involves introducing the transgenic DNA into embryonic stem cells (ES cells) derived from a mouse embryo at the very early stages of development.
During early embryonic development, XpdTTD is dominant over the Xpd † XPCS and Xpd † XP alleles, whereas later in the ontogenesis of skin, hair - shaft, and blood cells, the situation is reversed.
The gene, known as gata5, acts in embryonic cells, which are primordial, unspecialized cells that form in the earliest stage of embryonic development and are genetically programmed to evolve into one of many specialized cell types, such as skeletal muscle cells, nerve cells, blood cells, skin cells, and liver cells.
Professor Martinez - Arias and colleagues, supported by the European Research Council and the Wellcome Trust, have reconstructed these early stages of development using mouse embryonic stem cells.
Researchers at the University of Cambridge have managed to reconstruct the early stage of mammalian development using embryonic stem cells, showing that a critical mass of cells — not too few, but not too many — is needed for the cells to being self - organising into the correct structure for an embryo to form.
Impact of bisphenol - A on early embryonic development and reproductive maturation.
Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.
They are present during the early stages of embryonic development and possess the ability to become, or «differentiate,» into almost any tissue within the body.
«The current extension of induced pluripotency to human cells is a major development and although it is early days for this technique it may well prove to be every bit as signifcant as the first derivation of human embryonic stem cells nine years ago.
In the future, these cells could be molecularly manipulated to better grasp their interactions and the early embryonic development stages, hypothesizes Dr. Christos Coutifaris, president - elect of the American Society for Reproductive Medicine and a professor at the University of Pennsylvania.
Newly evolved genes can rapidly assume control over fundamental functions during early embryonic development, report scientists from the University of Chicago.
Early in embryonic development, the neural crest — a transient group of stem cells — gives rise to parts of the nervous system and several other tissues.
Embryonic stem cells are obtained from early embryos (between 5.5 and 7.5 days of development post-fertilization).
Unlike embryonic stem cells from earlier in development, fetal stem cells from umbilical cord blood are multipotent - they can develop into a limited number of cell types.
These findings on gene expression in single embryonic stem cells are in concert with recent studies of early mammalian development, which reveal molecular heterogeneity and a stochasticity of gene expression in blastomeres.
The sequential appearance of genes specific to early developmental stages matches the timing of their induction during embryonic development.
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