One form of breast cancer called «triple negative» breast cancer is known for its biological aggressiveness and lack
of effective chemotherapy options.
Not exact matches
In the case
of my illness, the prescribed first round
of radiation and
chemotherapy did its job
of making the eventual surgery
effective.
In a beautifully ironic twist for a natural chemical falsely accused
of causing stomach cancer, capsaicin has been shown to be «absolutely
effective» in alleviating the pain from oral stomatitis, mouth sores caused by cancer
chemotherapy and radiation treatments, according to Dr. Ann M. Berger
of Yale University's Pain Management Center.
A particularly
effective treatment against many cancers, platinum - based
chemotherapy, has the unfortunate side effect
of damaging the hair cells in the ear that are responsible for sensing sound waves, Goldrich said.
Not all
chemotherapy drugs are equally
effective for all people, and finding the best treatment for an individual is a painful process
of trial and error that wastes time and exposes patients to toxic side effects.
A majority
of patients (80 %) experience a relapse after their initial treatment with
chemotherapy, therefore a more
effective line
of treatment is needed.
Frequent, low - dose
chemotherapy regimens avoid this effect and may therefore be more
effective at treating certain types
of breast and pancreatic cancer, according to the murine study «Metronomic
chemotherapy prevents therapy - induced stromal activation and induction
of tumor - initiating cells,» which will be published online November 23 in The Journal
of Experimental Medicine.
In a continuation
of this work, Goldman is also using mathematical modeling to pursue the most
effective dose
of chemotherapy to induce the vulnerable transition state
of the cancer cell demonstrated in this research.
Scientists in Korea have discovered that using antibacterial soap when hand - washing is no more
effective than using plain soap, according to a paper published today in the Journal
of Antimicrobial
Chemotherapy.
«These findings are important for cancer treatments, as currently there are no drug therapies for enchondromas and there are no universally
effective chemotherapies for chondrosarcomas,» said senior author Benjamin Alman, M.D., chair
of the Orthopaedic Surgery Department at Duke University Medical Center.
After surgical removal, radiation, and
chemotherapy, this type
of tumor often returns; drugs are then usually no longer
effective.
The team's recent study in mice has found that the treatment reduced the mass
of ovarian cancer tumors and was more
effective at suppressing tumor growth than
chemotherapy.
«We hope that our test will significantly improve the odds
of survival
of breast cancer patients by allowing doctors to identify the most
effective but least toxic form
of chemotherapy for each individual patient before the treatment begins.»
Dr Fiona Blackhall, a senior lecturer in The University
of Manchester's Institute
of Cancer Sciences and a consultant based at The Christie NHS Foundation Trust — both part
of the Manchester Cancer Research Centre — said: «In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup
of their individual cancer, we need to compare how
effective the new targeted treatment is compared to standard
chemotherapy treatment.»
A drug used to treat men with late - stage prostate cancer proved
effective in stemming progression
of the disease in research participants who had not yet received
chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (OHSU).
One example: A consensus panel convened by the National Institutes
of Health, after reviewing medical literature, concluded in November 1997 that «there is clear evidence that needle acupuncture treatment is
effective for postoperative and
chemotherapy nausea and vomiting, nausea
of pregnancy, and postoperative dental pain.»
Only one class
of chemotherapy called taxanes is
effective against the disease.
But in the meantime, it would help if we could identify who won't benefit from standard treatment, so we can spare them the debilitating effects
of chemotherapy and get them into clinical trials for experimental therapies that might be more
effective.»
UCLA scientists have unlocked an important mechanism that allows
chemotherapy - carrying nanoparticles — extremely small objects between 1 and 100 nanometers (a billionth
of a meter)-- to directly access pancreatic cancer tumors, thereby improving the ability to kill cancer cells and hence leading to more
effective treatment outcome
of the disease.
More than 80 percent
of women with advanced stage high - grade serous ovarian cancer experience relapses even after repeated surgeries and multiple rounds
of chemotherapy, and this
effective new approach to treat the disease could be a major step forward in preventing cancer from returning.
Tamara Minko, professor in the Ernest Mario School
of Pharmacy, and Lorna Rodriguez, professor
of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical School, say because there is not a good screening method for ovarian cancer, most women with the disease are not diagnosed until after it has metastasized to other organs and surgery and
chemotherapy are not as
effective.
Doctors also used chemicals and radiation to obliterate his bone marrow, the source
of all his blood cells — a crude but
effective strategy to destroy any cancerous ones that survived
chemotherapy.
The safety study sets the stage for phase II clinical trials looking at whether high dose vitamin C is
effective at extending overall lifespan and quality
of life for patients undergoing radiation and
chemotherapy.
«This is a promising treatment option that may prove not only to be more
effective than
chemotherapy alone prior to surgery, it may also be better than
chemotherapy and standard radiation,» said lead study author Kimmen Quan, MD, a radiation oncologist at the University
of Pittsburgh Medical Center.
Chemotherapy has been shown to be
effective in a wide range
of patients, but one
of its main problems is the emergence
of resistance against the anti-tumor drug used.
Reasoning that the selected T cells, to be
effective, would have to make up the bulk
of cells in each patient's immune system, the team administered
chemotherapy to the patients to temporarily wipe out substantial numbers
of existing immune cells.
Research from the University
of Southampton has shown a drug, used in combination with
chemotherapy to treat advanced colorectal cancer, is not
effective in some settings, and indeed may result in more rapid cancer progression.
In such cases, the patient will be treated with a cocktail
of chemotherapy instead
of a more appropriately targeted treatment, which could be more
effective and gentler on the patient.
A University
of Rochester team found a way to make
chemotherapy more
effective, by stopping a cellular quality - control mechanism, according to a study published in Nature Communications.
Patients usually receive surgery,
chemotherapy and radiation, but these treatments are not very
effective as an estimated 50 percent
of GBM patients die within one year, and 90 percent die within three years.
The collection contains over 20,000 different samples
of Salmonella, with half
of the samples housed at the Cancer Research Center where researchers affiliated with MU focus on three areas
of cancer research: early detection, targeted treatment and new,
effective chemotherapy.
Surgery, radiation and
chemotherapy do prolong survival by several months, but targeted therapies, which have been
effective with other forms
of cancer, have not lengthened survival in patients fighting glioblastoma.
It is a scary diagnosis, and even though
chemotherapy can be
effective as standard -
of - care, many...
Our surgical oncologists provide the highest - quality cancer care to diagnose and remove tumors, debulk tumors to help make
chemotherapy or radiation therapy more
effective, and relieve symptoms or side effects
of therapies.
Further, depending on the specific type
of cancer,
chemotherapy is not always
effective.
January 14, 2000 Protein predicts prognosis for breast cancer patients Low levels
of E-cadherin, a protein that links cells together, appears to be the single most
effective factor for predicting which patients with early breast cancer will need
chemotherapy following surgery.
Surgeons can remove the initial tumor, radiation therapy is
effective in treating disease that has reached nearby lymph nodes, and
chemotherapy can decrease the risk
of distant metastases.
Low levels
of a protein that helps link cells together appears to be the single most
effective factor for predicting which patients with early breast cancer will need
chemotherapy following surgery, report researchers from the University
of Chicago Medical Center in the January 15, 2000 issue
of Cancer Research.
WESTMINSTER, CO (October 10, 2012)-- Researchers may soon be able to add yet another item to the list
of exercise's well - documented health benefits: A preliminary study suggests that when cancer survivors exercise for several weeks after they finish
chemotherapy, their immune systems remodel themselves to become more
effective, potentially fending off future incidences
of cancer.
Immunotherapy has been an
effective treatment for patients with certain types
of cancer that have been resistant to
chemotherapy and radiation treatment (e.g., melanoma)
It is a scary diagnosis, and even though
chemotherapy can be
effective as standard -
of - care, many patients become resistant to treatment.
Summary: Low levels
of E-cadherin, a protein that links cells together, appears to be the single most
effective factor for predicting which patients with early breast cancer will need
chemotherapy following surgery.
Further, most cancer treatments are based on damaging cancer cells, so understanding why a
chemotherapy works, and for which patients, should lead to more
effective and less toxic treatments that will increase the cure rate and improve quality
of life for cancer survivors.
Led by Leena Gandhi, MD, PhD, associate professor
of medicine and director
of thoracic medical oncology, researchers from the KEYNOTE - 021 study demonstrated for the first time that combining an immune checkpoint inhibitor — in this case, pembrolizumab — with a platinum - doublet
chemotherapy regimen might be more
effective than
chemotherapy alone as first - line treatment for advanced, non-squamous NSCLC.
Linking the differentiation process with organ - on - a-chip technology pioneered by his team, the researchers went on to engineer the first in vitro model
of the human glomerulus, demonstrating
effective and selective filtration
of blood proteins and podocyte toxicity induced by a
chemotherapy drug in vitro.
Laura Donnelly Thousands
of women with the most deadly form
of breast cancer could be given hope by a breakthrough treatment which could make
chemotherapy effective.
Replacing the
chemotherapy with a safe, side - effect - free treatment would mean that the established programs for immune system restoration could immediately expand to become a useful,
effective treatment for immunosenescence, the age - related failure
of the immune system.
Dissolving polymer wafers soaked with
chemotherapy drugs were being implanted near tumors, but Stephan knew that T cells, which are capable
of «squeezing throughout the entire tumor bed,» would be more
effective than drugs, which can only penetrate a millimeter or so into tissue.
Researchers note that while PCI - aided delivery
of chemotherapy to the brain has proven
effective in laboratory tests, additional testing prior to human clinical trials is needed to identify other less - toxic blood - brain barrier agents to be used in tandem with the photosensitizer in the PCI process.
The findings signify that immunotherapy is more
effective than
chemotherapy in managing this type
of cancer.