Sentences with phrase «of effective new therapies»

Hear about the Science Exchange's Reproducibility Initiative, which aims to reward high - quality, reproducible research and provide a mechanism for industry to identify robust new drug targets for the development of effective new therapies.

Not exact matches

Like effective and respectful therapy, persuasion brings about new wants and aims, but it does so, not by coercion or by frustrating desires, but by opening new possibilities, which is the result of divine «creativity.»
The principles that have emerged thus far are these: We should seek new knowledge of our genes (and we can say this without deciding whether the Human Genome Initiative is the wisest and most cost - effective way to do so) We should seek therapies for the genetic disorders that afflict many people.
Creator of an effective new model of relationship repair (Emotionally Focused Couple Therapy), she has written numerous articles and trained thousands of therapists around the world.
A number of new, highly effective therapies to treat both Hepatitis C and HIV / AIDS have been approved by the Food and Drug Administration in recent years, but their extraordinary costs have raised questions about states» ability to pay the sticker price.
While many researchers have tried to identify effective new therapies to mitigate motor function impairment and enhance quality - of - life, discoveries have been lacking.
Not so, the authors of the new research suggest: The three therapies were equally effective.
Despite current standard of care, the prognosis for patients with PDAC is poor and effective new therapies are needed.
«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.
«Unsuspected characteristics of new cystic fibrosis drugs found, offering potential paths to more effective therapies
«Early diagnosis, effective therapy vital for treatment of deadly invasive aspergillosis: New guidelines focus on new treatments, early diagnosis of fungal infection.&raqNew guidelines focus on new treatments, early diagnosis of fungal infection.&raqnew treatments, early diagnosis of fungal infection.»
«By helping us understand that lower levels of RNF125 confer resistance to BRAF inhibitors, we have a new strategy to stratify patients for currently approved therapy versus participation for human clinical trials to investigate whether targeting JAK1 will be more effective in patients whose tumors exhibit reduced RNF125,» said Keith T. Flaherty, M.D., associate professor, Harvard Medical School, and director of Developmental Therapeutics, Cancer Center, Massachusetts General Hospital, and co-author of the study.
Hormone replacement therapy (HRT) is the most effective treatment for menopausal symptoms, in particular for younger women at the onset of the menopause, suggests a new review published today (19 December) in The Obstetrician & Gynaecologist (TOG).
Payment vouchers eliminated price differences between an older generic therapy called clopidogrel and a newer, more effective version of the therapy, ticagrelor.
The new therapy has successfully gone through a pilot study with six patients conducted at the Singapore National Eye Centre and has yielded exceptional results, having shown to be both safe and effective in the treatment of glaucoma.
Electroconvulsive therapy remains one of the most effective treatments for severe depression, but new UNSW research shows ultra-brief pulse stimulation is almost as effective as standard ECT, with far fewer cognitive side effects.
«Our findings may not only help to understand the causes of depression, but also may provide a new biochemical target for developing more effective therapies
The NIHR Leicester Respiratory Biomedical Research Unit — a partnership between the University of Leicester and Leicester's Hospitals — focuses on promoting the development of new and effective therapies for the treatment of respiratory diseases including severe asthma and chronic obstructive pulmonary disease (COPD).
«The complex pathophysiology of schizophrenia and resultant patient heterogeneity present significant challenges to developing new and effective therapies for this disorder,» said corresponding author Dr. Bruce Kinon of Lundbeck LLC.
And while new therapies have been effective in releasing the immune system's restraints to unleash the body's own cancer - fighting powers, they only work in about half of melanoma patients and often lose their potency as the cancer develops resistance.
«At Exeter we are already developing specific psychological therapies, running clinical trials of novel drug approaches and using - cutting edge genetic techniques to identify new targets for safe and effective therapies and to allow us to use current treatments in a more focussed way.»
A new study published in the International Journal of Molecular Sciences, describes a new concept of how these two cancers may evolve in a similar way and may eventually lead to more effective therapies for both.
According to Saura, «this study opens up new perspectives on therapeutic prevention and treatment of Alzheimer's disease, given that we have demonstrated that a gene therapy which activates the Crtc1 protein is effective in preventing the loss of memory in lab mice».
«This could help revolutionize cardiology research by improving the ability to efficiently discover, design, develop and deliver new therapies for the treatment of heart disease, and by providing more efficient screening tools to identify and prevent cardiac side effects, ultimately leading to safer and more effective treatments for patients suffering from heart disease.»
The real value of the new research may be that these receptors can provide new and more effective therapies for current addicts, says Michael Nader, a physiologist and pharmacologist at the Wake Forest University School of Medicine in Winston - Salem, N.C. «This identifies a target,» he says.
Knowing what these defenses are could lead to new ways of making existing therapies more effective.
«The turbulent healing powers of plasma: By revealing the origins of turbulence, new computer simulations may lead to more effective medical therapies using plasma.»
He adds, «We have shown in a previous study that mindfulness group therapy is just as effective as individual CBT for the treatment of typical depression and anxiety symptoms; something we also observed in the new study.»
The results from our new study suggest that entinostat may enhance the anti-tumor efficacy of PD - 1 targeted therapy through MDSC targeting, potentially providing an effective combination treatment approach for patients with solid tumors, including lung and renal cell carcinoma.»
While a new generation of safer, more effective oral medications to treat hepatitis C patients may cost tens of thousands of dollars for a 12 - week regiment, investing in these new therapies could generate savings estimated at more than $ 3.2 billion annually in the U.S. and five European countries, according to a new study (abstract 228) released today at Digestive Disease Week ® (DDW) 2015.
The field has experienced monumental challenges developing new and effective drug therapies, not the least of which was the discovery that — until recently - clinical trials were conducted where up to 30 % of participants did not have the Alzheimer's disease - related brain change targeted by the experimental drug.
More than 11,880 new cases of GBM were estimated to occur in 2015, with overall survival averaging 12 to 15 months, so there is an urgent need for more effective therapies.
«Although surgical therapy is remarkable and effective, it is incumbent on us to move to a higher genetic level of understanding of these diseases,» said senior author John Elefteriades, M.D., the William W. L. Glenn Professor of Surgery (Section of Cardiac Surgery) at Yale School of Medicine, and director of the Aortic Institute at Yale - New Haven Hospital.
Scientists have been trying to identify antibodies that can attack all strains of the Ebola virus; this new technology will improve their chances of developing an effective therapy.
New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.
Treatment success rate of drug - resistant tuberculosis in HIV - positive patients is low and requires more effective regimen using new drugs compatible with antiretroviral therapy.
«It suggests to us that targeting the pathways used in regulating cell fate decisions — how stem cells choose between cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to potential new therapies
UCLA Researchers are dedicated to understanding the mysteries of how the brain develops and works, what goes wrong in brain diseases, and developing effective new therapies to treat diseases from brain tumors, depression and Alzheimer's disease.
High throughput screening in motor neurons is a new approach to identifying effective therapy for SMA, said Lee L. Rubin, PhD, Senior Vice President for Research and Development and Chief Scientific Officer for Curis, Inc., and former Professor of Anatomy and Developmental Biology and Director of the Eisai Institute at University College in London.
This strategy is expected to improve early diagnoses and intervention, predict the course of a disease, identify new drug targets and select the most effective therapies for individual patients.
At 13 different New Jersey locations, our pediatric specialists partner with families to make our many innovative therapies and medical treatments more personalized and effective... so children can achieve more of their goals.
For a therapy involving new cancer medicines to be effective, the mutation status of the tumour must be known.
At thirteen different New Jersey locations, our pediatric specialists partner with families to make our many innovative therapies and medical treatments more personalized and effective... so children can achieve more of their goals.
Additional insight into the biology of ER - positive breast cancers, particularly the higher risk luminal B cancers, could aid in identifying potential targets and new, effective therapies.
The new studies identify activation of endothelial Toll - like receptor 4 by Gram - negative bacteria as a critical event in formation of cerebral cavernous malformations, a significant predisposing condition for stroke and seizure for which effective medical therapies are lacking.
The Lymphoma Program is dedicated to the integration of laboratory and clinical research to increase our understanding of lymphoma and to develop new, more effective therapies for these conditions.
These results reveal new risk markers in the genome that could be used to predict which children are likely to respond poorly to albuterol and other current first - line anti-asthma drugs, and to guide the development of new therapies that will be more effective and reduce the outsize burden of mortality in minority populations.
CAR T - cell therapy targeting B - cell maturation protein may be a new effective type of immunotherapy treatment for patients with multiple myeloma.
New research into CAR - T cell therapy has revealed crucial mechanisms that could help the immunotherapy technique, which is currently only effective against blood cancers, be adapted for the treatment of brain tumors and other forms of solid cancers.
The Leukemia Program is dedicated to integrating laboratory and clinical research to increase our understanding of leukemia and to develop new, more effective therapies for the disease.
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