However, the development
of effective vaccines and readily accessible tests (to identify infected cats) have together significantly reduced the prevalence (frequency) of infection with this virus, although it remains an important disease.
Access to clean water, modern sanitation, efficient insect control, and the advent
of effective vaccines to target childhood disease may have made us complacent.
TRANSVAC is a new infrastructure project - funded by the European Commission in the context of Horizon 2020 - that aims to accelerate the development
of effective vaccines urgently needed to address European and global health challenges with the ultimate goal to build an efficient and sustainable collaboration of experts and facilities to catalyse vaccine research in Europe.
Dr Odile Leroy, Executive Director of the European Vaccine Initiative (EVI) and coordinator of TRANSVAC2, said: «The TRANSVAC2 activities will further strengthen the vaccine R&D infrastructure in Europe and will thereby accelerate the development
of effective vaccines that are urgently needed to address global health challenges».
This understanding of how HIV - 1's «invisibility cloak» works could lead to the development
of effective vaccines against HIV - 1.
TRANSVAC is an infrastructure project that aims to accelerate the development
of effective vaccines...
But scientific and economic obstacles have stymied the development
of effective vaccines against many of the developing world's most deadly diseases, such as malaria and HIV as well as pneumococcus, the leading vaccine - preventable killer of children under the age of five.
Before the introduction
of an effective vaccine, rotavirus was the top cause of diarrhea - related deaths in young children.
As new disease strains continue to develop, and globalization and travel make it easier to pass disease across geographical borders, the ability to whip up huge quantities
of effective vaccine is becoming increasingly important.
This makes the development
of an effective vaccine to protect against infection, as well as antiviral therapy to combat already - existing infections, particularly challenging,» says Dr. Grant Hansman, a virologist who leads the CHS Research Group on Noroviruses at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and Heidelberg University.
Batista was one of a number of scientists involved in the study from the Ragon Institute, established in the Boston area by experts from Massachusetts General Hospital, Harvard University and the Massachusetts Institute of Technology, with the goal of working toward development
of an effective vaccine against HIV / AIDS.
Their Asian Elephant project has completed the re-assembly of the genome of the herpes virus that is killing many young elephants, so now the development
of an effective vaccine will be able to proceed for the first time.
It is a major constraint to livestock production throughout subSaharan Africa, and it threatens to invade the Americas, yet there is no immediate prospect
of an effective vaccine.
For example, the UK government's program for tackling HIV and AIDS in the developing world, which was published shortly after the Bangkok meeting, makes the unqualified comment that the enterprise «will accelerate research and development
of an effective vaccine.»
Fortunately, the prevalence of FeLV in cats has decreased significantly in the past 25 years since the development
of an effective vaccine and accurate testing procedures.
Not exact matches
They're doing this very strategically by trying to incorporate as much
of the variability and mutational changes to make sure the
vaccine is
effective.»
A part
of the research will include analyzing exactly why this year's flu
vaccine proved so ineffective against the most common strains circulating (the shot was just 25 %
effective against influenza A strains).
We can't test the efficacy
of the flu
vaccine because everyone knows it's
effective.
In the battle against cervical cancer, can fewer injections
of the
vaccine be just as
effective in adolescents?
Given questions about how long the
vaccine is
effective for, she questioned the efficacy
of giving shots to girls as young as 11 years old in parts
of the world (such as the U.S.) where women regularly undergo safety Pap screening repeatedly over their lifetimes, saying that the chances
of their contracting cervical cancer may be less than the «small» risks associated with the
vaccine.
Yes, although most
of the time when your baby has a low fever or a mild cold, it's still safe and
effective to get the
vaccine.
They don't care that
vaccines are 80 %
effective in individuals and the protection
of the cocoon effect outweighs the small risk
of individual bad reactions, because some woman on Baby Bump got the flu shot during pregnancy and her daughter has developmental delays and she thinks it might have something to do with the
vaccine.
Like all
vaccines, «anti D' is not 100 per cent
effective in all cases, however, it can help protect the health
of future pregnancies for many women.
After all,
vaccines are
effective because they contain weak traces
of the viruses they protect against.
And because most
vaccines are not 100 percent
effective (they protect 85 to 95 percent
of children who get them), your child may be at risk around unvaccinated kids even if he's up to date on his shots.
A well conducted study published in the Italian medical journals in June 2007 demonstrated that the daily intake
of Colostrum can be 3x more
effective than the flu
vaccine for providing protection.
Even the best
vaccines are not 100 %
effective, and we can't vaccinate 100 %
of the population.
Preliminary estimates by the federal CDC show this year's version
of the flu
vaccine is 36 percent
effective against all strains
of the flu, but just 25 percent
effective against the H3N2 strain causing most flu cases this winter.
The Hepatitis A
vaccine or immune globulin is only
effective within two weeks
of exposure to the virus.
There is an
effective vaccine available for horses recommended by the American Association
of Equine Practitioners (AAEP).
The researchers are currently planning a follow - up study which will test whether a flu
vaccine is more
effective for the elderly when combined with brief use
of Losmapimod.
This new method will enable the
effective production
of RNA - based
vaccines and promote the development and adoption
of RNA - based plant protection methods.
Efficacy is the measure
of how
effective a
vaccine is at protecting the overall population.
An
effective genital herpes
vaccine is needed to eliminate this complication
of HSV - 2 infection.»
«The
vaccine was virtually 100 percent
effective in preventing disease in these young individuals,» says Dr. Daron G. Ferris, professor in the Department
of Obstetrics and Gynecology at the Medical College
of Georgia and at the Georgia Cancer Center at Augusta University.
In their always engrossing, often grotesque account, journalist Bill Wasik and veterinarian Monica Murphy trace the illness's history, detailing the many futile methods
of combating the disease (including the original «hair
of the dog:» binding into a patient's wound a hair from the animal that infected him) before Louis Pasteur's rabies
vaccine became the first
effective treatment in 1885.
«Understanding the fundamental biology
of how our immune system works will lead to the development
of more
effective drugs and
vaccines,» said Kanneganti, corresponding author on the paper.
Exactly which organization or nation might fund the mass production
of these
vaccines, assuming they prove
effective, also remains an open question.
By dissecting the heritage
of these cells, we can find new targets to tackle a range
of conditions including infectious diseases, cancers and immune disorders, and even make
vaccines more
effective.»
«I don't think we have the perfect plan,» admits Margolis, but like
vaccine research itself, it's part
of a stepwise process that should, with time, see
effective vaccines go to the people who need them the most.
To date, only six patients (including Menezes) for whom the vaccination strategy failed have survived, the first was 6 year - old Matthew Winkler from Ohio, who was bitten by a rabid bat in 1970 and developed symptoms after receiving a full course
of the
vaccine (prior versions
of the rabies
vaccine were not as
effective as current formulations).
Dr. David Cavanagh,
of the University
of Edinburgh's School
of Biological Sciences, who led the study, said: «There is a desperate need for an
effective vaccine, which can be made easily in large quantities, to protect against this devastating disease.
Second, mass free distribution
of bed nets, medicines, and
vaccines can be highly
effective and properly managed.
An interdisciplinary team from The University
of Texas Medical Branch at Galveston and Profectus BioSciences, Inc. has developed a quick - acting
vaccine that is both safe and
effective with a single dose against the Ebola strain that killed thousands
of people in West Africa last year.
«The matching process is not a perfect science, therefore, in some flu seasons, the
vaccine available in the fall is not a good match for the circulating virus strains and is less effective,» said senior author David Weiner, Ph.D., Executive Vice President and Director of the Vaccine and Immune Therapy Center at The Wistar Ins
vaccine available in the fall is not a good match for the circulating virus strains and is less
effective,» said senior author David Weiner, Ph.D., Executive Vice President and Director
of the
Vaccine and Immune Therapy Center at The Wistar Ins
Vaccine and Immune Therapy Center at The Wistar Institute.
He pointed to the sudden rise in share prices for pharmaceutical firms working on Ebola
vaccines as one type
of economic spur to ensure that medicines are there in an emergency, along with WHO's capacity to «prequalify» drugs as safe and
effective so that they can be sold more cheaply and widely.
Remarkably, the researchers also found that blocking this protein in mice protected them from the lethal effects
of dengue virus infection, an important finding given that an
effective vaccine against dengue has remained elusive, partly because there are four serotypes
of the virus that cause disease.
Although Merck's
vaccine will be marketed only for cervical cancer, preliminary evidence suggests it may also be
effective against penile, anal, and vulvar cancers and even certain cancers
of the head and neck.
One
of the most crucial and elusive goals
of an
effective HIV
vaccine is to stimulate antibodies that can attack the virus even as it relentlessly mutates.
The 9vHPV
vaccine was also highly
effective at reducing the risk
of having HPV 31/33/45 / 52 / 58 - associated cervical cell abnormalities, biopsies, and definitive therapies.