Sentences with phrase «of effectiveness of these drugs»

Not exact matches

Sidenote: Chew is also one of the few biopharma execs I've ever spoken to who voluntarily brought up the Institute for Clinical and Economic Review (ICER), a tough drug pricing critic organization which insists on proven outcomes (and has consequently become a major biopharma gadfly), because the group actually validated the cost - effectiveness of Omada's tech.

The endorsement came despite lingering questions about safety and effectiveness, but also followed a high - stakes pressure campaign in which the manufacturer accused the Food and Drug Administration of gender bias, since several pills were already approved for men with sexual problems.

But payers are highly reluctant to cover the $ 300,000 drug without a record of proven effectiveness.

The study, just published in Science, showed that the creation of what the researchers are calling microtumors can help predict drug effectiveness in cancer patients better than the current standard method of testing the drugs on rodents.

Pagan said that a larger, more comprehensive study must be done before determining the drug's true impact, but if the drug's effectiveness is confirmed in such tests, nilotinib could become the first treatment to impede the killing of brain cells that's consistent with Parkinson's, according to NPR.

On November 8, the US House of Representatives held a hearing on the effectiveness of a 1999 law known as the Kingpin Act, which is used to sanction individuals suspected of involvement in the drug trade.

And don't worry, the lower cost doesn't mean the drug is less effective — brand and generic drugs have the same standards of quality and clinical effectiveness.

This generally supports the case that Living Goods offers high quality products, but because our experience on the site visit may have been non-representative and there are many other potential factors that may affect the effectiveness of drug treatments aside from following storage procedures for drugs properly, we consider it to be only weak evidence in support of the quality of Living Goods» drug treatments.

If they want their drugs to be provided in those wards and if they want it to be eligible for that forced savings dollars, they have to price it at a level of cost effectiveness that the Singaporean government likes.

If there is a competitive drug market, with limited advantage offered by the new drug in terms of increased effectiveness or reduced side effects, the drug will probably not win substantial market share in its product category.

Based on conversation with physician experts, SunTrust said it believes LJPC - 501 hits on multiple characteristics of a successful drug, including effectiveness at improving MAP, a good safety profile, easily titratable and positive mortality benefit as supported by a statistically significant reduction in CV SOFA score.

The new drug nevirapine's effectiveness is similar to that of AZT, yet the cost is only a tenth as high, less than $ 5 per child.

Being one of the most thoroughly researched plants ever; it's been claimed to match the effectiveness of drugs including statins like liptor, corticosteroids, antidepressants, anti-inflammatories, and drugs for chemotherapy and diabetes.

Earlier this year, the Journal of the American Medical Association warned that the «safety, effectiveness, and accuracy» of child and baby health monitoring devices are not checked or approved by the Food and Drug Administration.

While the recommendations on this site represent the opinions of the doctors and are based upon the best of their knowledge, experience and training as to safety and effectiveness, these recommendations have not been reviewed by the U.S. Food and Drug Administration.

St. John's wort can interact with many other drugs and can decrease the effectiveness of oral contraceptives.

The Home Office cites falling drug use in the UK as evidence its policies are working, but critics point out illegal drug use is falling internationally and is probably not connected to the effectiveness of government policy.

The letter to the prime minister, signed by actress Julie Christie, singer Sting, former defence secretary and Home Office minister Bob Ainsworth and a collection of former chief constables and leading lawyers, calls on Downing Street to implement «a swift and transparent review of the effectiveness of current drug policies».

A new report has questioned the effectiveness of random drug testing in schools, calling for further evidence on their probable impact.

Governor Cuomo last week in his State of the State Address announced a plan to allow 20 hospitals across the state to prescribe the drug, saying New York would monitor the program and evaluate its effectiveness.

While ZMapp seemed to help more people survive an Ebola infection, it narrowly missed the statistical threshold that researchers set to prove the drug's effectiveness, according to the new study, published in the New England Journal of Medicine.

They also believe that by measuring a patient's dark adaptation response time they have developed a tool that can help track the onset or progression of the disease as well as measure the effectiveness of drugs that are in development to treat the disease early on.

«More research is needed on the effectiveness of users conducting their own drug - testing.

To guide the spending of that money, the National Institute of Medicine made a priority list of situations for which data about outcomes are badly needed — for instance, comparing the effectiveness of various medical and behavioral interventions to prevent the elderly from falling (the complications of which are a leading cause of death), comparing assorted drugs and surgeries alone or in combination in the treatment of specific cancers, comparing the effectiveness of different implants and devices for treating hearing loss, and so forth.

With this kind of review process, if 20 studies of the effectiveness of a truly ineffective drug are conducted, and one of them shows a significant effect with a p - value of 0.05 because of chance alone, investigators for the other 19 studies not showing any effect would presumably not be inhibited from writing up and submitting reports of these for publication out of fear that they'll be denied publication because of their nonsignificant results.

In 2010, Malaysia introduced voluntary «cure and care» treatment centres providing methadone that began to replace many compulsory centres but government and public resistance to closure of compulsory detention remains high because of a zero - tolerance approach to drugs and a lack of recognition of the effectiveness of voluntary centres.

Making an antivenom requires samples of venom, but if the mix varies substantially from place to place, this will affect the drug's effectiveness and reliability.

Nicotine can lower the effectiveness of certain medications or interfere with the way the way drugs work; it can also impact healing and lead to infection and greater discomfort after surgery.

When a class of drugs called triptans became available in the early 1990s, Healy used them, but over time their effectiveness dimmed.

Professor Adeeba Kamarulzaman, an author on the study from University of Malaya, Malaysia, said: «In recent years, compulsory drug detention centres in Malaysia and across Asia have come under scrutiny and question over their lack of effectiveness in treating addiction and their human rights transgressions.

Writing in a linked Comment, Gino Vumbaca from Harm Reduction Australia, said: «Evidence on the effectiveness of compulsory and voluntary drug dependence treatment in the Asian region has been scarce and this study is a much needed addition to the evidence base that is required to inform policy making... The present study provides solid evidence in support of urgent need to expand availability of and access to evidence based voluntary drug dependence treatment approaches to all whom are affected by drug dependence.

Although the effectiveness of the new drug is not the main concern of a phase I trial, Dr. Williamson noted it was promising that five of the patients survived more than a year after starting the drug.

The hydrogel, placed in the spot where the tumor was removed, releases the drug over an extended period of time, lengthening the window of effectiveness.

The NAPOLI - 1 (NAnoliPOsomaL Irinotecan) Phase 3 study — a final confirmation of a drug's safety and effectiveness — was conducted among patients with metastatic pancreatic cancer who previously received gemcitibine, which has been the standard - of - care therapy for such patients.

«Researcher develops, proves effectiveness of new drug for spinal muscular atrophy.»

Yet the NIH allocates less than 1 percent of its $ 30 billion annual budget to «comparative effectiveness research,» the kind needed to sort out the surgeries, drugs, and devices that work from those that do not.

The agency has ongoing research examining the effectiveness of drugs such as methadone, buprenorphine, and naltrexone that are used to wean people off of stronger opioids, as well as research developing alternatives such as vaccines and transcranial magnetic stimulation to treat opioid addictions.

Because not all the trials of the drug have been published, she says, there are «serious doubts» about the drug's effectiveness.

St. Jude Children's Research Hospital leads study showing that a drug withdrawn from the market in 2010 may enhance the effectiveness of bone marrow transplants for select pediatric leukemia patients

She suggests that one - and two - year survival data may provide more information about the effectiveness of these drugs than overall median survival rates.

To test the safety and effectiveness of microdosing, the researchers delivered a common drug ophthalmologists use to dilate the pupil and examine the back of the eye.

Published in the journal Molecular Cancer Therapeutics, the study also found that use of a second inhibitor might improve the effectiveness of these drugs by possibly preventing resistance, and it recommends that clinical trials should be designed to include a second inhibitor.

In a new Essay publishing 28 December in the open access journal PLOS Biology, Kristofer Wollein Waldetoft and Sam P. Brown of Georgia Institute of Technology propose that development of alternative therapies for mild infections could help slow the development and spread of antibiotic resistance, thereby preserving the drugs» effectiveness for use in severe infections.

«Blood pressure drug may boost effectiveness of lung cancer treatment.»

«We urgently need new treatments for lung cancer patients, and this research suggests we can boost the effectiveness of an existing drug, rather than switch to another new expensive treatment.

This makes it an exciting drug target, but until now, it has been difficult to test the effectiveness of potential new drugs on blocking the protein.

Researchers from the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester, who led the study, warned that failure to take the drugs correctly, known as «non-adherence», reduced their effectiveness and may lead to a worsening of patients» disease.

These first results are extremely encouraging and mean we can plan a phase 3 trial to better evaluate the effectiveness of the drug.»

Tanyi and colleagues therefore hope in future to enhance the effectiveness of their vaccine by combining it with other drugs that deactivate tumor anti-immune defenses.

For example, the results of one study, known as UPLIFT, one of four large - scale studies conducted in 2008, demonstrated the effectiveness and safety of a drug called Spirivain about 6,000 patients with respiratory disease.