Sentences with phrase «of effects of the disease»

Although the most visible sign of polio is paralysis; only one percent of the effects of the disease is likely to be paralysis.

«This study extends the narrative that many of the effects of disease - related genetic variation are specific to a certain context, such as a given immune cell type,» said Barbara Stranger, PhD, University of Chicago, senior study author.

The results indicate that menopause has a significant impact on the level and rate of functional decline in women with rheumatoid arthritis and is associated with a worsening progression of the effects of the disease.

AIDS in Africa: Its Present and Future Impact by Tony Barnett and Piers Blaikie (Belhaven Press, pp 193, # 9.99) is a detailed and fascinating analysis of the effects of the disease on households, farming and industry in the continent first widely affected by AIDS.

Importantly, only approximately one ‐ quarter of individuals with the mutations manifest the disease; this incomplete penetrance is also likely a consequence of the effects of disease ‐ modifying genes, environmental influences, or both in a given individual.

This design leads to the consequence that disease in one part of the brain will inevitably affect the function of the others and that many of the effects of the disease can be partly compensated for by the network.

However, any data obtained from iPS is a combination of effects of the disease's genetic mutation and the recombination - related genetic modifications (often random).

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

Hall's coral studies focus on the effects of heat, acidification, and disease, which help scientists find and breed particularly resilient candidates for replanting on reefs.

The American Beverage Association dismissed the study in a statement, saying it did «not show that consuming sugar - sweetened beverages causes chronic diseases and the authors themselves acknowledge that they are at best estimating effects of sugar - sweetened beverage consumption.»

UniQure, for example, has developed a drug called Glybera, which is essentially a virus that reverses the effects of LPLD, a disease that prevents people from breaking down fats and can cause increased risk of pancreatitis.

Gene therapy is, in essence, a type of biotechnology that replaces mutated genes with healthy ones, reversing the effects of disease or damage.

He also noted that many drugs aimed at lessening the effects of Alzheimer's disease work by attempting to improve this attention mechanism.

Zuckerberg may have pledged part of his immense wealth to fighting disease — his Facebook stake is worth nearly $ 50 billion — but his company has no subsidiary attempting to reverse the effects of aging.

Unless you're one of the 1 % of Americans who suffer from celiac disease, gluten probably won't have a negative effect on you.

«Hitler was not insane or deranged, or suffering from drug - induced delusions,» he writes, «or laboring under the effects of some chronic disease such as syphilis, or acting in an unresolved hypnotic trance: on the contrary, he was sane according to any reasonable definition of the term, and fully responsible for his actions.»

A new, extensive five - year study on the effects of cocoa flavanols on cardiovascular disease is slated to begin in 2015 and will hopefully reveal more about the antioxidant's impact on memory.

In diseases such as malaria and sickle cell disease, red blood cells break down, with harmful effects on the rest of the body — particularly the lining of small blood vessels.

High loonie due to petrodollar effect = > loss of profit margin due to decline in final US selling price wrt Canadian dollar costs = > layoffs = > Dutch Disease.

Intermittent Fasting is proving to be a simple and effective strategy for avoiding major dietary changes while achieving strong effects not just for one disease risk factor, but for an array of factors that constitutes the foundation for metabolic syndrome, cardiovascular disease, cancer, and possibly neurodegenerative diseases.

This team also discovered 3,200 genes that had fewer loss - of - function or missense mutations than would be expected suggesting that these are likely disease - causing variants that are rare or absent in the population because of their detrimental effect on human health.

While the study examined weight loss and the psychological effects, it also looked at the physiological ramifications of things such as disease prevention in the areas of diabetes, breast cancer, and cardiovascular disease.

In this first article, a summary is given of how and where the banana export trades began, the early history of Panama disease, and the important effect that the disease had on the development of this industry.

Jungle disease, illness and the effects of malnutrition were rife, yet sick men were often forced to continue with the brutal work day and night in searing temperatures.

then it would put more funding into diseases that effect everyone on the planet, not just when it comes walking down the streets of New York, London or Paris.

Drug company scientists develop a drug with a range of physiological effects, none of which are terribly helpful, so the marketers must identify and promote a disease for the drug to treat....

While some programs also encourage abstinence or noncoital sex, most are concerned with teaching techniques for «safe sex»; offspring (and disease) are thus treated as (equally) avoidable side effects of sexuality, whose true purpose is only individual pleasure.

Global Health Now recently captured photographs of a community in Kahemba under the ill effects of this disease.

Researchers have determined that Konzo is a motor neuron disease caused by the toxic effects of cassava consumption.

Similarly, ecology recognizes the deleterious effects of mono - cultures and their susceptibility to predation, disease, and other stochastic events.

Hatred, fear, boredom, and hopelessness are often the sources of disease, and love, courage, high purpose, and hope are then needed to effect a cure.

Booth was aware that there is a physical component in the disease and wrote of «treating the passion as a disease, as we should any other physical affection, bringing to bear upon it every agency, hygienic and otherwise, calculated to effect a cure.»

If the mind is diseased then that does not effect the soul of the person.

If six out of every hundred persons who went swimming at a certain beach contracted a disease that had all sorts of destructive effects, it would certainly be regarded as a question of public morals and safety.»

They have developed a habit of consistently taking vitamins because they have been told that, in the long run, vitamin supplements are going to have a beneficial effect on their physical health, resistance to disease, and general well - being.

World Vision ACT: S, the organization's network of young people living according to the Book of Acts, now has a campaign called ACT: S to End Malaria that educates people on the far - reaching effects of the disease.

People refusing medical treatment because they think they can pray disease away, The demoralizing way religion makes you feel about yourself (I am a wretch, a sinner, a bad person by nature), the religious wars that have been fought for millenia, the self righteous passing laws based on THEIR beliefs (change to the pledge of allegience which now excludes anyone who does not believe in a fairy godfather, the change to the national motto that turned it into the lie «in god we trust», the bigotry that «my religion is the right one and you are wrong so I'll pray for you» kind of crap... don't you realize that it is insulting to me when someone says they will pray for me... its the same as saying I'm going to do something for you but there won't be any effect, so it is just a waste of time.

We read in 21st Century Science and Health with Key to the Scriptures, «If hypnotism seems to heal disease — or mental collective noise seems to alleviate loneliness — this appearance is deceptive, since error can not remove the effects of error.

Once more, the use of powerful drugs to cure disease may, while serving this wanted end, also have deleterious genetic effects.

if belief in white apples on mars caused wars, impeded civil rights and medical progress, and aided the spread of disease (not to mention had the effect of making us mindless, irrational zombies), we'd be against that, too!

If this is so then it is hardly surprising that significant sections of the majority - dominant community treats any symptoms of what they consider the disease of conversion as a foreign body, whose nauseating effects are not to be merely treated, but surgically excised.

Of course, we do need to be concerned about the problem of venereal disease still with us and about the side effects of contraceptiveOf course, we do need to be concerned about the problem of venereal disease still with us and about the side effects of contraceptiveof venereal disease still with us and about the side effects of contraceptiveof contraceptives.

Even though alcoholism ranks as one of the country's three major health problems, along with cancer and heart disease; even though it accounts for approximately 98,000 deaths every year; even though it is the root cause of most pastoral - care crises (suicides, auto fatalities, child abuse, divorces, hospital admissions, accidental deaths and home violence); even though it costs the nation $ 120 billion annually in terms of lost work time, health and welfare benefits, property damage, medical expenses, insurance and lost wages; and even though its effects impair the educational process of every child in every classroom, still the church acts as though alcoholism does not exist.

With all the commercialization of drugs, promoting made up diseases and disorders, these companies are already brainwashing this country that everyone is sick and if you take there littel pill you can» sleep better, get rid of skin disorders, etc.» The side effects are worse than the dsupposed disorder to begin with.

Actually, since cancer is a disease of old age, which kicks in long after most people have done whatever procreating they're going to do, it has zero effect on long - term survivability of the species.

Antioxidants are substances that help to prevent the damaging effects of oxidation in the body, and diseases related to aging.

And the recent amendment to Codex recommendations reflects evidence that while people with coeliac disease can tolerate a low level of gluten without ill effects, some people are more sensitive and can only safely eat foods with less than 20ppm of gluten.

The problem of course was cholesterol and its effect on heart disease.

Anthocyanins, the antioxidants responsible for giving blueberries their color, protect cells from the damaging effects of oxidation, which is often linked to chronic conditions like heart disease and cancer.