Sentences with phrase «of effects on insulin»

While xylitol has no known toxicity to humans, it can cause hypoglycemia (low blood sugar) and liver failure in dogs as a result of its effects on insulin regulation.

If, on the other hand, the macronutrient composition affects fat accumulation, then these subjects should lose both weight and fat on the carbohydrate - restricted regime and their energy expenditure should increase, supporting the idea that a calorie of carbohydrate is more fattening than one from protein or fat, presumably because of the effect on insulin.

This unfavorable effect on glucose tolerance in women, accompanied by an apparent lack of an effect on insulin sensitivity, suggests that short - term ADF may be more beneficial in men than in women in reducing type 2 diabetes risk.»

Not exact matches

When in their natural state, Cacao beans (aka food of the gods) present a wide array of nutrients like magnesium and antioxidants not to mention their positive effect on our cardiovascular health and our insulin sensitivity.

In fact, one of the primary studied benefits in this regard is the effect that cacao has on improving insulin resistance and downregulating inflammation caused by obesity (6).

The effects of fat and protein on glycemic responses in nondiabetic humans vary with waist circumference, fasting plasma insulin, and dietary fiber intake

This is why it is imperative that you are completely aware of the effects that insulin injections can have on the body, and that is exactly what you are going to learn below.

Atkins rejects the advice of the food pyramid, instead asserting that the tremendous increase in refined carbohydrates is responsible for the rise in metabolic disorders of the 20th century, and that the focus on the detrimental effects of dietary fat has actually contributed to the obesity problem by increasing the proportion of insulin - inducing foods in the diet.

These findings provide the first evidence of a direct effect of maternal metabolism on fetal brain activity and suggest that central insulin resistance may be programmed during fetal development.»

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

The boosted genes had three main effects: improving cellular energy efficiency; upping insulin production, which improves control of blood sugar; and preventing the breakdown of caps on chromosomes that help prevent cells wearing out and ageing.

Suppressing glucagon with leptin had the same effect on mice as making insulin: it reduced blood levels of glucose.

The researchers examined the in vitro effects of insulin - like growth factor 1 (IGF - 1) on lithium sensitivity in blood cell lines of both lithium - responsive and non-responsive bipolar patients.

The new test instead looks for hGH's knock - on effects in the body — namely, increased production of insulin - like growth factor 1 (IGF - 1) and a substance called P3NP.

«A number of scientists are working on the effect of estrogens on pancreatic insulin - producing cells,» says Sandra Handgraaf, a researcher at the Faculty of Medicine and the first author of this work.

Years of diabetes research carried out on mice whose DNA had been altered with a human growth hormone gene is now ripe for reinterpretation after a new study by researchers at KU Leuven confirms that the gene had an unintended effect on the mice's insulin production, a key variable in diabetes research.

The study, published in PLOS ONE, is the first to consider the differing effects of dietary fats on prediabetes as two separate conditions, although previous studies have shown that dietary fats have an effect on insulin sensitivity.

For example, the beneficial effects of weight reduction and bariatric surgery on improving insulin resistance are known, but their role in decreasing PDAC incidence is still essentially unknown.

These trends may be explained in part by the yo - yo effects that high glycemic - index carbohydrates have on blood glucose, which can stimulate fat production and inflammation, increase overall caloric intake and lower insulin sensitivity, says David Ludwig, director of the obesity program at Children's Hospital Boston.

He illustrated the effect the law has on the economy with the case of the pharmaceuticals company Hoechst, which has been waiting for a licence to produce insulin using biotechnology for eight years.

Researchers at the University of California, Riverside have tested a genetically - modified (GM) soybean oil used in restaurants and found that while it induces less obesity and insulin resistance than conventional soybean oil, its effects on diabetes and fatty liver are similar to those of conventional soybean oil.

Atkins rejects the advice of the food pyramid, instead asserting that the tremendous increase in refined carbohydrates is responsible for the rise in metabolic disorders of the 20th century, and that the focus on the detrimental effects of dietary fat has actually contributed to the obesity problem by increasing the proportion of insulin - inducing foods in the diet.

In the present studies, the effects of musculoskeletal loading on serum osteocalcin in db / db mice were correlated with improvements in glycemic control and insulin sensitivity, but it is important to note that total, rather than undercarboxylated, osteocalcin was measured here.

For more clear - cut evidence that snails use insulin as a weapon, Joanna Gajewiak, a research assistant professor at the university, came up with a fast way to synthesize enough of the insulin to directly test its effects on fish.

They discovered that giving the mice antibiotics produced very different effects on their gut microbiomes, as well as on their insulin sensitivity, tissue inflammation and related metabolic functions such as blood glucose, depending on the genetic background of the mouse.

«One end of the molecule binds to p110 forming a key pathway that is needed for the metabolic effects of insulin on glucose metabolism.

Researchers have shown that lowered levels of c - myc can modestly slow aging and extend life in mice, with some evidence that this is due to effects on insulin metabolism, though there is a still a lot of investigation needed to take that as a firm conclusion.

The effect of insulin on phosphorylation of Akt protein was measured by Western blot in enhanced hiPS - HEP cells from C18 on Day 12 post-thawing (n = 3 for the [+] condition; n = 1 for the -LSB----RSB- control).

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high - fat - fed mice.

Therefore, the mechanism proposed behind decreased female central insulin sensitivity is a modulation caused by brain estrogen signaling, potentially mediated by estrogen effects on ERα in various regions of the hypothalamus.

Gender effect on insulin sensitivity and secretion in different categories of glucose tolerance

Effect of preculturing human satellite cell cultures in increasing concentrations of insulin on the activity constant A0.5 of GS.

A long series of laboratory and epidemiologic studies has suggested that cutting back on sleep has a harmful effect on glucose control, insulin secretion and metabolism in ways that might increase diabetes risk, said Eve Van Cauter, professor of medicine at the University of Chicago and senior author of the study.

Effect of preculturing human satellite cell cultures in increasing concentrations of insulin on the basal and insulin - stimulated glucose transport activity in cultures of human myofibers.

Differential effects of nebivolol and metoprolol on insulin sensitivity and plasminogen activator inhibitor in the metabolic syndrome.

In accordance, Jackson et al. (9) showed that preculturing at 0.1 μmol / l insulin decreased the effect of acute insulin stimulation on glucose transport.

Acute insulin stimulation increased glucose transport by 21 % in control cultures precultured at 1 pmol / l insulin, but at higher insulin concentrations we could not detect an effect of insulin on glucose uptake.

Furthermore, female rats were more sensitive to the anorectic effects of centrally injected leptin rather than male rats, which on the contrary were more sensitive to centrally injected insulin (262, 263).

In accordance with other studies, we found an increased glucose uptake under acute insulin stimulation in cultures established from control subjects precultured under basal physiological insulin concentrations, but when precultured at a higher insulin concentration, we could not see an effect on acute insulin stimulation indicative of induced insulin resistance (10).

Effect of salsalate on insulin action, secretion, and clearance in nondiabetic, insulin - resistant individuals: a randomized, placebo - controlled study.

Sex - specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility

Nevertheless, the more subtle effects on body size that we observe in Drosophila body size at 25 °C may be because the level of GBP expressed is within the range where it begins to suppress growth, even if the effects in insulin secretion are below our level of detection.

Lewandowski's team examined the effects of artificially stressing the heart on several indicators of metabolic health, and found that at early stages, they're all good — increased glucose tolerance and insulin sensitivity and changes in fat that make it burn energy.

Symposia X: The Impact of Heat Shock Protein Expression on Muscle Metabolism, Exercise Capacity and Disease Prevention Speakers will present evidence for the functional effects and mechanisms of heat shock proteins and their role in aging, mitochondrial function, apoptotic pathways, insulin sensitivity, myocardial protection and more.

To study the effects of hyperinsulinemia on atherosclerosis, Rask - Madsen and his colleagues created mice with fewer insulin receptors in every tissue of the body and compared them to mice with intact insulin receptors.

We will also focus on lipid signalling and lipid - controlled cell biology, and examine the effect of sphingo - and phospholipids on endocytosis, lipid trafficking, and insulin secretion.

Whitehead N, White H. Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.

Our strong expertise allows us study lipid - protein interaction based phenomena at different scales, from the organ and cellular systems down to minimal synthetic systems in which we can control the proteins as well as the lipid, for instance to monitor the allosteric effects of specific lipids on fundamental receptors such as the EGF receptor (Coskun et al (2011) PNAS) and the insulin receptor.

Researchers publishing in the Journal of Physiology examined the effects of a high fat and sugar diet during mouse pregnancy on maternal glucose tolerance and insulin resistance and on feto - placental glucose metabolism.

Polymorphisms in five of 15 genes (33 %) encoding molecules known to primarily influence pancreatic beta - cell function - ABCC8 (sulphonylurea receptor), KCNJ11 (KIR6.2), SLC2A2 (GLUT2), HNF4A (HNF4alpha), and INS (insulin)- significantly altered disease risk, and in three genes, the risk allele, haplotype, or both had a biologically consistent effect on a relevant physiological trait in the QT study.