Contribution
of electrostatic interactions, compactness and quaternary structure to protein thermostability: lessons from structural genomics of Thermotoga maritima.
This finding, along with a few other papers last year, emphasizes the importance
of electrostatic interactions for protein stability, he says, and will enable protein chemists to create more stable protein - based drugs.
Not exact matches
«The negative surface charge
of nanoparticles enabled
electrostatic interactions with therapeutics thus resulting in the slow release
of therapeutics.»
Charge separation on peptides creates permanent dipole moments that can be aligned with an electric field to provide optimal orientation
of the molecules and the amount
of peptide immobilised can also be tuned by the
electrostatic interactions when the peptides have an overall charge.
However, when the pairing
of a rare - earth element and an oxygen vacancy is created in the material, this pair possesses a positive net charge and therefore, inhibits the trapping
of protons due to the
electrostatic repulsive
interaction.
The atoms within a compound can be held together by a variety
of interactions, ranging from covalent bonds to
electrostatic forces in ionic bonds.
Recent successful steps in this direction were for example identifying that hydrophobic mismatch and
electrostatic interaction with the lipid PIP2 are driving the formation
of active complexes
of the SNARE protein synatxin - 1 in plasma membrane.
SELECTED ACHIEVEMENTS • Developed a project as part
of the high school pilot project series in a bid to assist students understand the methodologies for ribonucleic acid encapsulation • Increased student interest in laboratory work by introducing real time lab projects including minor
electrostatic interactions with DNA • Decreased the number
of high school students opting out
of chemistry class by 30 % by implementing chemistry concepts through non-conventional methods
of teaching • Introduced interactive curriculum development to the school which brought about much interest from students willing to become part
of the chemistry lesson planning activities