Citation: Canham MA, Sharov AA, Ko MSH, Brickman JM (2010) Functional Heterogeneity
of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript.
Studies
of embryonic stem cells revealed that NANOG protein levels can be lowered by a chemical process known as methylation, which involves putting a methyl group chemical tag on a protein's messenger RNA (mRNA) precursor.
Not exact matches
By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into
cells, the team
revealed a key interaction that regulates the ability
of embryonic stem cells to change into other
cell types.
Use
of the immunofluorescent microscopy visualization technique
reveals the presence
of specific proteins in naive human
embryonic stem cells.
Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has
revealed a new understanding
of how an open genome structure supports the long - term and unrestricted developmental potential in
embryonic stem cells.
Spatial organization
of embryonic stem cell responsiveness to autocrine gp130 ligands
reveals an autoregulatory
stem cell niche.
Scientists investigating the mechanisms
of Down Syndrome (DS) have
revealed the earliest developmental changes in
embryonic stem cells caused by an extra copy
of human chromosome 21 — the aberrant inheritance
of which results in the condition.
More Efficient, Effective Approach to
Stem Cell Creation Dr. Ding's approach is one of a kind, but his work builds on a revolutionary discovery by another Gladstone scientist — Nobel Laureate Shinya Yamanaka, MD, PhD, who in 2007 revealed a process for transforming adult skin cells into cells that look and act like embryonic stem ce
Stem Cell Creation Dr. Ding's approach is one
of a kind, but his work builds on a revolutionary discovery by another Gladstone scientist — Nobel Laureate Shinya Yamanaka, MD, PhD, who in 2007
revealed a process for transforming adult skin
cells into
cells that look and act like
embryonic stem ce
stem cells.
High Throughput Screening for Inhibitors
of Rest in Neural Derivatives
of Human
Embryonic Stem Cells Reveals a Chemical Compound that Promotes Expression
of Neuronal Genes
Endogenous optical signals
reveal changes
of elastin and collagen organization during differentiation
of mouse
embryonic stem cells.
This investigation
reveals that the Maryland Commission is keeping with the trend
of investing more money in ethical
stem cell research as opposed to
embryonic as it is this route which is providing demonstrable results.
Reference: September 13, 2007 issue
of Cell Stem Cell under the title «Whole - Genome Mapping
of Histone H3Lys4 and 27 Trimethylations
Reveals Distinct Genomic Compartments in Human
Embryonic Stem Cells».
Studies in cultured
embryonic stem (ES)
cells, and our analysis
of zebrafish embryos have
revealed that pluripotency is characterized by a unique chromatin signature.
10/10/2007 Researchers
Reveal Repressor Protein Blocks Neural
Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... Mor
Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety
of processes also blocks
embryonic neural
stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... Mor
stem cells from differentiating into neurons, according to a study by University
of California, San Diego and Howard Hughes Me... More...
These findings on gene expression in single
embryonic stem cells are in concert with recent studies
of early mammalian development, which
reveal molecular heterogeneity and a stochasticity
of gene expression in blastomeres.