10.30 - 11.00 Stackebradt, Erko (Professor, Leibnitz Institute, DSMZ - German Collection of Microorganisms and Cell Cultures; Coordinator, MIRRI - Microbial Resource Research Infrastructure, Braunschweig, Germany): Scientists and (their) microbial resources: responsibilities revisited 11.00 - 11.30 Balázs, Ervin (Member of HAS, Professor, Director - general, Centre for Agricultural Reserch, Hungarian Academy of Science, Martonvárár, Hungary): Microbes serving agri - food industry 11.30 - 12.00 Coffee break 12.00 - 12.30 Nagy, Károly (Professor, Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary): How science supports management
of emerging infections 12.30 - 13.00 Rajnavölgyi, Éva (Professor, Department of Immunology, University of Debrecen, Debrecen, Hungary): Human life in invisible company - The significance of preventive vaccination
The Zika diagnostics project in Brazil was brought underway by the DZIF through a fast track grant procedure in order to appropriately tackle the danger
of emerging infections.
Stephen Morse: When I suggested influenza in 1990 as a paradigm
of an emerging infection, (Nobel laureate) Howard Temin, a mentor of mine, disagreed.
Not exact matches
Kids are more likely to pick up an
infection than an adult, probably because
of children's tendency to put their fingers in their mouths, and you may notice worms
emerging in your family when your littlies begin day care and school.
GBS
emerged as the predominant source
of newborn
infections in the 70s.
MRSA Action UK continues to campaign to raise awareness and to bring other
infections into the forefront
of the surveillance programme, to drive down the larger proportion
of infections that do not appear in the statistics and to tackle the regional variations and other
emerging threats in our hospitals and care facilities.
Staphylococcus epidermidis is increasingly
emerging as a cause
of multi-resistant hospital - acquired
infections.
They
emerge from UJI's current line
of reasearch into such enzyme - inhibiting structures, looking for ways to both mitigate the typical side - effects
of current treatment approaches and shift even the most resistant tropical
infections.
When the body fails to restock, life - threatening forms
of anemia, lethal
infections or serious bleeding disorders can
emerge.
The fungal
infection, which first
emerged six years ago, was reported May 29 in a seventh species
of North American bats — the largely cave - dwelling grays (Myotis grisecens).
«Instead, the bacterial reservoirs already in the bladder
emerge out
of the tissue, multiply and cause another
infection.»
High levels
of a protein called C - reactive protein (CRP), which has been linked to inflammation and
infection,
emerged from an analysis
of more than 100 proteins as being strongly linked to delirium.
A recent study published in PLoS ONE, a peer - reviewed scientific journal, provides new information for public health officials on mitigating the spread
of infection from
emerging flu viruses.
But much
of the United States, including the Southeast, has been left out
of the equation, despite
emerging evidence that Lyme or a Lyme - like
infection may be present there as well.
This work began as part
of a biodefense grant from the National Institutes
of Health, screening a library
of 30,000 compounds for activity against the envelope
of Nipah virus, an
emerging infection first identified in 1999 in Malaysia.
The EID2 database used in the study was created by University researchers in the Institute
of Infection and Global Health to bring a «big data» approach to
emerging diseases.
What
emerged from their work was the finding that the girl had inherited two differently mutated copies
of the gene IRF7, which encodes a protein that amplifies the production
of interferon, a critical part
of the body's response to viral
infections.
Among the affected microorganisms were three that commonly cause deadly hospital - acquired
infections, including Staphylococcus aureus and two
emerging bacterial pathogens, Stenotrophomonas maltophilia and Acinetobacter baumannii, that are a growing cause
of infections in hospital intensive - care units.
R5 viruses are exclusively associated with primary
infection, and X4 viruses
emerge in later stages
of HIV diseases in half
of HIV carriers.
«Strengthened
infection control practices and having a powerful active surveillance program for acute respiratory illnesses are key to the rapid and prompt response for
emerging respiratory
infections,» cautions lead author I.S. Al - Abaidani, MD, Department
of Communicable Disease, Ministry
of Health, Oman.
The comeback
of antibiotic - resistant
infections «would dramatically alter the practice
of medicine,» says microbiologist Alexander Sulakvelidze, a phage expert at the
Emerging Pathogens Institute at the University
of Florida in Gainesville.
Research Center for
Emerging Infections and Zoonoses (RIZ), University
of Veterinary Medicine, Hannover, Germany.
As more reports appear
of a grim «post-antibiotic era» ushered in by the rise
of drug - resistant bacteria, a new strategy for fighting
infection is
emerging that targets a patient's cells rather than those
of the invading pathogens.
Gates, whose foundation focuses on global health, «asked me whether the AAV - mediated approach could be used in the context
of a pandemic or
emerging infection,» Wilson recalls.
And though it's not a substitute for vaccines, hand washing is critical in preventing and controlling infectious disease, writes Joel C. Gaydos
of the Defense Department's Global
Emerging Infections Surveillance and Response System in a commentary accompanying the report.
And Haddow and colleagues reported in the August
Emerging Infectious Diseases that four
of eight macaques exposed to the virus vaginally developed
infections as did seven
of eight macaques that received the virus via the rectum.
«Being able to track the duration
of fevers and the return
of fevers could help us learn more about an influenza season as it is
emerging and possibly provide information about other
infections, including new
emerging infectious diseases,» Polgreen says.
Epigenetic translates to «above genetic» and is an
emerging field
of study that looks at how environmental factors — such as
infections, pollutants, stress and, in this case, long - term exposure to drugs that block estrogen synthesis — could influence a person's DNA.
Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process
of infection, according to a study led by researchers at the Icahn School
of Medicine at Mount Sinai and the National Institutes
of Health (NIH), and published today in the Nature Press journal
Emerging Microbes and
Infections.
For this survey
of global health, Science has joined forces with Science Translational Medicine, which examines vaccine development, strategies against
emerging infections, progress in point -
of - care diagnostics, and ways to promote mental health and neonatal health.
«The results
of our current study support the report on
emerging roles
of tRFs to viral
infections,» the researchers say.
Surprisingly, they found that although the patterns
of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern
of mutations in the cells was actually similar between the tumors —
of either type — that had
emerged in patients who had had
infections with either hepatitis C or B, and were different in patients without such
infections.
The threads collected data on tissue health (e.g. pressure, stress, strain and temperature), pH and glucose levels that can be used to determine such things as how a wound is healing, whether
infection is
emerging, or whether the body's chemistry is out
of balance.
Although there are animal models
of TB
infection, results can be slow to
emerge and also can be costly.
An
emerging controller
of the cholinergic effect
of inflammation is micro-RNA-132 (5), whose involvement with post-stroke recovery awaits further studies and might open new venues for more rigorous assessment
of the post-stroke risk
of survival and systematic
infection and the identification
of conceptually novel targets for therapeutic interference.
«C. diff
infection over the last decade has
emerged as a threat to patients, especially the most vulnerable and the elderly, and has increased in incidence and severity,» says Sanjay Saint, M.D., MPH, lead author
of the new paper.
Tom Solomon, director
of the United Kingdom's Health Protection Research Unit in
Emerging Infections based at the University
of Liverpool, says he is also considering a trial
of the therapy in humans.
«Aspirin is a widely used cardiovascular preventive drug and also has an
emerging role in cancer treatment and prevention,» said Valerie O'Donnell, Ph.D., Division
of Infection and Immunity, Cardiff University, and the study's lead author.
The UIC Epicenter for Prevention
of Healthcare Associated
Infections will study how healthcare workers can care for patients with
emerging infectious diseases without putting themselves at risk.
William Castell, chair
of the Wellcome Trust, praised Farrar in a statement as «one
of the foremost scientists
of his generation, whose work — much
of it funded by the Trust — has contributed to better understanding, surveillance, prevention and treatment
of diseases including
emerging infections, influenza, tuberculosis, typhoid and dengue.»
The agency plans to double the number
of sites in the
Emerging Infections Program — a research and surveillance network
of labs, clinics, and state health departments — from 10 to 20.
Through this research, a rough account is
emerging of how HERV - W could trigger diseases like schizophrenia, bipolar disorder, and MS.. Although the body works hard to keep its ERVs under tight control,
infections around the time
of birth destabilize this tense standoff.
The bacterial isolates came from urine samples from two patients in Atlanta - area hospitals as part
of the nationwide Multi-site Gram - Negative Surveillance Initiative, part
of the CDC - funded
Emerging Infections Program.
«The challenge will now be to use ancient viral sequences for looking back in time, which may prove insightful for predicting the long - term consequences
of newly
emerging viral
infections.
TB has
emerged as the leading cause
of death due to a single pathogen: deaths attributable to TB now exceed those due to HIV
infection (1.5 million vs 1.2 million in 2014 according to WHO).
One such
infection is West Nile virus, which is an
emerging virus that is asymptomatic in 80 %
of infections.1 However, the incident
of severe
infection is raised by 20 % in the over 60s, as discussed by Montgomery in this CEI review.
A specific focus
of WBVR is research on
infection biology, immunology and vaccinology
of relevant veterinary and human, current and
emerging infectious diseases.
Detection
of Hantaviruses and Arenaviruzses in three - toed jerboas from the Inner Mongolia Autonomous Region, China — Zhiqiang Wu —
Emerging Microbes &
Infections
Additional uses include precise diagnosis
of microbial
infection, describing transmission patterns, understanding the genomics
of emerging drug resistance and identifying targets for new therapeutics and vaccines.
By integrating the sequence data and the associated metadata, we have established laboratory and bioinformatics - based methods that enable us to investigate scientific questions including: the tropism
of ZIKV for dendritic cells and the antiviral response
of the cells during
infection (Bowen et al. 2017); investigating the phylogenetic diversity
of strains obtained by Biodefense and
Emerging Infections (BEI) Resources and distributed to virologists (manuscript in preparation); the genetic determinants
of ZIKV host adaptation in C6 / 36 mosquito vs. Vero cells; and the diversity
of ZIKV circulating in limited geographic regions, including Barbados, Colombia, and the state
of Chiapas, Mexico.