PCR has also seen application in the identification
of emerging pathogens.
«We need a constellation of genes, including those for strain markers and toxins, that could be used to identify dangerous bacteria,» says Glenn Morris, director
of the Emerging Pathogens Institute at the University of Florida in Gainesville.
Among the most frightening
of the emerging pathogens is invasive MRSA, or methicillin - resistant Staphylococcus aureus.
«One of the things I think we humans will find ourselves facing on an ever greater frequency,» Shaw says, «is some kind
of an emerging pathogen that pops somewhere.»
B. salamandrivorans poses an extreme risk to European amphibian biodiversity and nations need to urgently consider appropriate biosecurity measures to stop the further spread
of this emerging pathogen.»
Not exact matches
During the session, a trio
of experts discussed the opportunities and challenges
of a more globalized world, including cross-border clinical trials, the spread
of disease and
emerging pathogens and managing supply chains.
«The other thing we're doing is continuing to survey for other
emerging pathogens, some
of them much less well known than these ones that the public at this point have heard a lot about.»
The deadly
pathogen first
emerged in the West Nile district
of Uganda in 1937, then lay dormant for about 20 years before it cropped up again in Israel in the 1950s and reappeared in Romania in 1996.
The Sigatoka disease complex is a cluster
of three closely related fungi — yellow sigatoka (Pseudocercospora musae), eumusae leaf spot (Pseudocercospora eumusae) and black sigatoka (Pseudocercospora fijiensis)-- which
emerged in quick succession during the last century as destructive
pathogens on banana.
South American native bumblebees (Hymenoptera: Apidae) infected by Nosema ceranae (Microsporidia), an
emerging pathogen of honeybees (Apis mellifera).
Globalization, changing climate, and the threat
of drug resistance have conspired to set the stage for that perfect microbial storm: a situation in which an
emerging pathogen — another HIV or smallpox, perhaps — might burst on the scene and kill millions before we can respond.
Haddow, who studies how
pathogens survive in the jungle and
emerge when humans encroach, had a great personal interest in Zika: His grandfather, Alexander Haddow, was one
of three scientists who had isolated the virus from a rhesus monkey in the Zika Forest near Entebbe, Uganda, in 1947 and described it in a paper in 1952.
A study just released in
Emerging Infectious Diseases suggests that the researcher, Brian Foy
of Colorado State University in Fort Collins, passed to his wife the Zika virus, an obscure
pathogen that causes joint pains and extreme fatigue.
An extensive investigation
of that epidemic by CDC concluded that 73 %
of the population was infected, an impressive number that suddenly made Zika an
emerging pathogen to watch.
Among the affected microorganisms were three that commonly cause deadly hospital - acquired infections, including Staphylococcus aureus and two
emerging bacterial
pathogens, Stenotrophomonas maltophilia and Acinetobacter baumannii, that are a growing cause
of infections in hospital intensive - care units.
The comeback
of antibiotic - resistant infections «would dramatically alter the practice
of medicine,» says microbiologist Alexander Sulakvelidze, a phage expert at the
Emerging Pathogens Institute at the University
of Florida in Gainesville.
As more reports appear
of a grim «post-antibiotic era» ushered in by the rise
of drug - resistant bacteria, a new strategy for fighting infection is
emerging that targets a patient's cells rather than those
of the invading
pathogens.
Other big issues include combating antibiotic resistance in the U.S., stemming the opioid epidemic that has quadrupled overdose deaths in the U.S. since 1999 and remaining vigilant against the perennial onslaught
of influenza — as well as
emerging threats including tick - borne
pathogens.
Both Cardin and the representatives from DOD and DHS spoke favorably
of a tiering system for select agents — an
emerging idea among biodefense experts — under which facilities and researchers dealing with the most dangerous
pathogens would be subject to the most stringent controls.
«H58 is an example
of an
emerging multiple drug resistant
pathogen which is rapidly spreading around the world,» says Professor Gordon Dougan, senior author from the Sanger Institute.
Researchers examined one
of the largest outbreaks
of the
emerging drug - resistant fungal
pathogen C. auris to date.
Professor Barbara Schnierle, head
of the section «AIDS, New and
Emerging Pathogens»
of the division Virology at the Paul - Ehrlich - Institut and her team have investigated whether smaller more specific and less complex - to - be produced parts
of E2 would suffice for conferring a protective immune response.
Monoclonal antibodies, which bind to and neutralize specific
pathogens and toxins, have
emerged as one
of the most promising treatments for Ebola patients.
Researchers at Boyce Thompson Institute (BTI) and in
Emerging Pests and
Pathogens Research Laboratory at the USDA - Agricultural Research Service in Ithaca, NY, are among many investigators working to find a solution, and their recent publication sheds light on an important strategy for controlling the spread
of CLas.
New research demonstrates that harnessing competition among
pathogens inside a patient could extend the life
of existing drugs where resistance is already present and prevent resistance to new drugs from
emerging.
The plague bacterium, Yersinia pestis, is one
of the deadliest
pathogens in human history, sparking three major pandemics: the Plague
of Justinian, which struck the Roman Empire during the 6th and 8th centuries; the second plague pandemic, which first erupted in Europe in the mid-14th-century Black Death and continued to strike the continent in recurrent outbreaks until the mid-18th century; and the third plague pandemic, which
emerged in China during the late 19th century.
It looks as though the new virus did not
emerge directly from any known
pathogen, says Luis Enjuanes, a coronavirus expert at the National Center
of Biotechnology at the Autonomous University
of Madrid.
«Our study suggests that chickens could be a major source for transmission
of emerging MDR
pathogen, H. pullorum, from poultry to humans,» the investigators concluded.
TB has
emerged as the leading cause
of death due to a single
pathogen: deaths attributable to TB now exceed those due to HIV infection (1.5 million vs 1.2 million in 2014 according to WHO).
«But at the end
of the day... [this] is a reasonable biological story based on the best available data
of how a
pathogen emerges historically and came to dominate.»
Launched in 2009 as part
of USAID's
Emerging Pandemic Threats program, the Predict project was renewed in 2014 with a grant of $ 100 million over five years to develop a sprawling, searchable database of the zoonotic pathogens behind emerging pandemic threats in countries around th
Emerging Pandemic Threats program, the Predict project was renewed in 2014 with a grant
of $ 100 million over five years to develop a sprawling, searchable database
of the zoonotic
pathogens behind
emerging pandemic threats in countries around th
emerging pandemic threats in countries around the world.
The Deadly Chytrid Fungus: A Story
of an
Emerging Pathogen PLoS
Pathogens, 6 (1) DOI: 10.1371 / journal.ppat.1000550
Nanotheraputics for Antibiotic Resistent
Emerging Bacterial
pathogens (NAREB) European Research Infrastructures for Poverty Related Diseases (EURIPED) Biomarkers for enhanced vaccines immunosafety (BioVacSafe) European network
of vaccine research and development TRANSVAC Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
In this area, Sette's disease focus has shifted over the years from HIV, HBV and HCV to
emerging diseases and diseases
of potential biodefense concern to, most recently, diseases and
pathogens relevant to worldwide global health, including dengue viruses, malaria, tuberculosis, and trypanosome infections.
The Postdoctoral Immunologist will support the on - going programme
of vaccine development against
emerging pathogens.
NIAID's biodefense research is integrated into its larger
emerging and re ‐
emerging infectious diseases portfolio that uses sophisticated genomic and proteomic platforms focused on developing broad ‐ spectrum therapies effective against entire classes
of pathogens.
Assist disease control by providing up - to - date geographical information about known and newly -
emerging forms
of drug resistance, by examining genetic variation in the context
of how whole
pathogen genomes are evolving rather than as fragmentary information about individual genetic changes or polymorphisms.
Batrachochytrium salamandrivorans and the risk
of a second amphibian pandemic Chytridiomycosis, an
emerging infectious disease (EID) caused by two fungal
pathogens, Batrachochytrium dendrobatidis... AmphibiaWeb
Dr. Kleinman main interest is the intersection
of scientific investigation and policy development particularly in the fields
of transfusion safety,
emerging pathogens, and TRALI.
This pilot study was funded by the Canadian Institutes
of Health Research, and supported by the European Mobile Laboratory, a partner
of the (WHO)
Emerging and Dangerous
Pathogens Laboratory Network and the Global Outbreak Alert and Response Network.
Dr. Lanteri was a lecturer in immunology and virology (specializing in HIV and
emerging pathogens) for students attending the Master's degree program
of biochemistry from the University
of Nice - Sophia Antipolis, France.
Spironucleous salmonicida is an
emerging fish
pathogen commonly found in the intestinal tract
of salmon that often causes severe systemic infections with gross pathological symptoms and high mortality rates.
Pathogens include those on the NIAID Category A-C agents as well as
emerging and re-
emerging infectious disease organisms, each year for a period
of five years.
We are a consortium
of laboratories using state -
of - the - art structural biology methods to determine the 3 - D structures
of proteins from
pathogens in the NIAID Category A-C priority lists and organisms causing
emerging and re-
emerging infectious diseases.
Our results indicate that
S. argenteus has spread at a relatively rapid pace over the past 2 decades across northeastern Thailand and acquired multiple exotoxin and antibiotic resistance genes that have been linked previously with livestock - associated
S. aureus Our findings highlight the clinical importance and potential pathogenicity
of S. argenteus as a recently
emerging pathogen.
The CPM research and discovery programs bring together a dynamic and interactive team
of faculty in the Schools
of Medicine, Public Health, and Arts & Sciences, who enjoy cross-translational approaches to address critical research questions to better understand rare, neglected and / or
emerging pathogens.
A new commentary on the nature
of pathogens is raising startling new questions about the role that fundamental science research on evolution plays in the understanding
of emerging disease.
But when the baby
emerges, it is entering a world
of bacteria, some
of which are bad (
pathogens) but some
of which are good.
As a manufacturer
of non-toxic ultraviolet germicidal (UVGI or UV) sanitizing technology for the animal care industry, PetAirapy works with Dr. Kowalski to identify new, existing, and
emerging pathogens and how to quickly and safely eliminate them from the air and surfaces in animal care facilities and residences.
Gastroenterology: Enteric
Pathogens Management
of Acute Pain and Potential Future Options Urology: Catheters and Infections Endocrinology: Physiology and Management
of Cushing's Disease Cardiology: Utility
of Ultrasound in Mitral Valve Disease Dermatology:
Emerging Treatments Urology: Assessing Kidney Function and Evaluating Proteinuria