Sentences with phrase «of endocrine cells»

JAIN, R., et al. «Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells.»

Interestingly, isolated islets provide a superior platform for studying propagation of IAPP aggregates because islets retain the composition and organization of endocrine cells and the extracellular matrix, which is absent in isolated, cellular monolayers.

Accounting for about 1 percent of all pancreatic cancers, pNET is a cancer of the endocrine cells, known clinically as the islets of Langerhans, which exist in small clusters throughout the pancreas.

While changes in insulin secretion are unlikely to play a major role in the acute effects of SD, cellular stress in pancreatic tissue suggests that chronic SD may contribute to the loss or dysfunction of endocrine cells, and that these effects may be exacerbated by normal aging, say the researchers.

Not exact matches

«Fat cells can adopt a range of metabolic phenotypes, depending on physiological conditions and location in the body,» said James G. Granneman, Ph.D., a researcher involved in the work from the Center for Integrative Metabolic and Endocrine Research at the Wayne State University School of Medicine in Detroit, MI.

Ain attended the annual Endocrine Society meeting in Toronto, where Bryan Haugen, head of the endocrinology division at the University of Colorado School of Medicine, told Ain that several of his most popular cell lines were not actually thyroid cancer.

THE STUDY «Endocrine Regulation of Energy Metabolism by the Skeleton» by Na Kyung Lee et al., published in Cell, August 10, 2007.

Although the main function of gut endocrine cells is to regulate digestion, the Duke researchers found these cells also have nerve - like properties.

«Exercise - induced irisin may not only act as an endocrine factor capable of promoting the browning of white adipose tissue, but could also regulate bone metabolism by autocrine mechanisms,» said Chen, who also serves as faculty in the Cell, Molecular & Developmental Biology program at the Sackler School of Graduate Biomedical Sciences at Tufts.

What makes this technique novel is the accompaniment of an imaging agent known as Ga - 68 DOTATOC, which binds to somatostatin receptors in neuroendocrine cells that use the hormone somatostatin to mediate endocrine function, the release of neurotransmitters and cellular proliferation.

A number of radiotherapies that marry a small but potent amount of radioactive material and a targeted molecular compound have been gaining traction as progressive treatments for malignant NETs, which can develop wherever nerve cells and hormone - producing endocrine cells are present (e.g., gastrointestinal tract, pancreas, lungs, thyroid).

Study results will be presented tomorrow, March 6, at the Endocrine Society's 97th annual meeting, currently taking place in San Diego, Calif., by Poonamjot Deol, an assistant project scientist in the Department of Cell Biology and Neuroscience who is driving the project in the Sladek lab.

«Our work highlights the fact that we need to test the effects of potential endocrine disrupting chemicals in both rat and human cells to be able to accurately predict the risk,» said Professor Habert.

In pre-clinical experiments, hESC - derived cardiomyocytes engraft in damaged myocardium and appear to behave like native cells; hESC - derived islet cells engraft, produce the hormones of the endocrine pancreas, and appear to do so under homeostatic control; etc. \ n \ nThere is no evidence of teratomas from differentiated hESC - derived cells and minimal, if any, immune rejection.

Many things are being secreted, which the brain sort of modulates, like the defensins from Paneth cells, there are many endocrine cells, serotonin cells in the gut, enterochromaffin cells, which are under autonomic control, so that we now know that serotonin, as well as norepinephrine, can, under stress for example, increase in the lumen of the gut.

Mouse Pancreas Tissue Slice Culture Facilitates Long - Term Studies of Exocrine and Endocrine Cell Physiology in situ.

[5] D. Sarkar et al., «Cellular and extracellular programming of cell fate through engineered intracrine -, paracrine -, and endocrine - like mechanisms,» Biomaterials, 32:3053 − 61, 2011.

The portfolio includes U.S. and foreign patents and applications directed to culture, expansion and scale - up of pluripotent stem cells and cell types derived therefrom, various differentiation processes for production of mesendoderm, definitive endoderm, PEC - 01, and endocrine precursors, as well as claims directed to the Company's Encaptra ® macro-encapsulation device platform.

Another novel biomarker is proneurotensin, the precursor molecule of neurotensin, which is peripherally released from the endocrine - like N - cells of the small intestine after fat intake (49).

Melanocytes have the capacity to respond to a diverse number of extracellular signals, including UVR, endocrine signaling cascades that occur during pregnancy, micro-environments of the stem cell hair bulge vs. differentiated hair follicle niches, and hypoxic conditions found in metastatic melanoma tumors.

Vitamin D is converted into its active form primarily in the kidneys in an endocrine - regulated process, but a small amount of vitamin D activation occurs in nonrenal cells and is regulated by inflammation.

We have recently found that many of the endocrine disrupting compounds that reduce masculinization in animal studies by interfering with Leydig cell function and differentiation are potent inhibitors of prostaglandin (PG) synthesis (D. M. Kristensen et al., submitted for publication).

The light information registered by these cells is partially processed in the retina and subsequently forwarded to the brain for further processing and integration with other sensory systems, eventually leading to outputs such as endocrine regulation of behaviours.

Endocrine glands, which are special groups of cells, make hormones.

While various studies have shown that fluoride reduces the incidence of dental cavities and tooth decay, fluoride is an endocrine disruptor and studies confirm that fluoride is directly toxic to thyroid cells and causes thyroid cell death, suppressing thyroid activity.

Hormones are the regulatory biochemicals produced by our endocrine glands, whose job is to coordinate the behavior of our cells, controlling everything from appetite to the choices we make in dangerous situations.

N - acetylglucosamine is found in the brain, thyroid, small intenstine, live, testes, epithelial cells of the sebaceous and endocrine glands, and endothelial cells of blood vessels.

Newer research confirms many of the old findings on these chemicals — endocrine disruption (in adults and babies), thyroid disruption, and increase risk of cardiovascular disease, diabetes and liver enzyme abnormalities.3 And recently, the Yale School of Medicine found that BPA «causes the loss of connections of brain cells,» which increases the risk for memory problems and even depression.4

We show signs of weak immune systems (variations of primary immunodeficiency, CVID), and «extra» allergies and sensitivities (now known to be mostly from a newly and thus still poorly recognized widespread mast cell activation disease called MCAS, ICD - 10 code coming October 2016, read «Never Bet Against Occam» by L. Afrin, MD), as well as all manner of endocrine imbalances (esp low thyroid, and often adrenal fatigue), some mitochondrial disease and / or dysfunction and all manner and forms of dysautonomia, but especially POTS in the more severe cases.

It effects every tissue in your body including the uterus, cervix, and vagina, the endocrine (hormonal) system, brain cells, fat metabolism, thyroid hormone function, water balance, peripheral nerve myelin sheath synthesis, bone cells, energy production and thermogenesis, the immune system, survival and development of the embryo, and growth and development of the fetus.

«We exposed plants and human cells to the components of formulations, both mixed and separately, and measured toxicity and human cellular endocrine disruption below the direct toxicity experimentally measured threshold.

Bisphenol A is a known endocrine disruptor that can cause the growth of fat cells.

Bruce Blumberg at the University of California named these endocrine disruptors that make our fat cells not work well and that's contributing to our obesity.

The thyroid gland is one endocrine gland in a network of endocrine glands; it makes special groups of cells that make hormones.

Your thyroid, one of the largest endocrine glands, greatly influences almost every cell in your body.

By Elaine Moore 4/18/2018 «Austrian researchers have proposed that an intact mitochondrial function can guard the normal endocrine function of both the thyroid and ovarian feedback axis systems... Mitochondrial health of thyroid cells depends on having an adequate number of various substances, primarily iron, magnesium, zinc, selenium and CoQ10.»

We know that all kinds of crap we are exposed to are endocrine disruptors and we have no idea what the synergy is when you pile them up in your cells.

They are a communication system for the body, similar to the nerve impulse messages that move our muscles, but rather than through nerves, the message is sent by the endocrine glands secreting hormones, sending them from one set of cells to another.

Included in this bundle: Biodiversity and Human Interaction Biologists Cell Division Cellular Transport Chemistry of Life Ecology Evolution and Natural Selection Genetics Human Body General Terms Human Body Circulatory and Lymphatic Systems Human Body Digestive System Human Body Endocrine System Human Body Excretory System Human Body Integumentary System Human Body Muscular System Human Body Nervous System Human Body Respiratory System Human Body Skeletal System Photosynthesis and Cellular Respiration Plant Structure and Function Scientific Method Taxonomy The Cell Types of Science What is Life

Below are some of the common specialty areas that we have experience with: - Infectious diseases: Tick - borne disease (Lyme disease, Ehrlichiosis, Rocky Mountain Spotted Fever, Bartonella), systemic and local bacterial infections, feline and canine viral disease - Hematology: Immune - mediated hemolytic anemia, thrombocytopenia, leukemia, bone marrow diseases - Oncology: Surgical and chemotherapy management, lymphoma, mast cell tumors, hemangiosarcoma, osteosarcoma, fibrosarcoma, mammary neoplasia, as well as benign and malignant skin masses such as adenomas and cysts - Urology: Kidney failure, bladder infections, stones / crystals, prostatic disease, pyelonephritis, FLUTD, protein - losing nephropathy, glomerulonephritis - Endocrine: Hormonal diseases such as hyper - and hypothyroidism, diabetes mellitus, cushings disease, addison's disease, endocrine skin disease - Gastroenterology: Chronic vomiting and / or diarrhea, inflammatory bowel disease (IBD), stomach ulcers / gastritis, colitis, pancreatic disorders, liver disease, protein - losing enteropathy - Respiratory disease: Feline asthma, canine chronic bronchitis, upper respiratory viral disease, pleural effusion, laryngeal paralysis - Cardiology: Heart murmurs and arrhythmias, heart failure, heartworm disease, hypertension - Ophthalmology: Gaucoma, cataracts, uveitis, corneal disease, ocular surgery - Allergic disease: Allergic dermatitis, food allergies, flea allergy, and allergic gastrointestinal and respiratorEndocrine: Hormonal diseases such as hyper - and hypothyroidism, diabetes mellitus, cushings disease, addison's disease, endocrine skin disease - Gastroenterology: Chronic vomiting and / or diarrhea, inflammatory bowel disease (IBD), stomach ulcers / gastritis, colitis, pancreatic disorders, liver disease, protein - losing enteropathy - Respiratory disease: Feline asthma, canine chronic bronchitis, upper respiratory viral disease, pleural effusion, laryngeal paralysis - Cardiology: Heart murmurs and arrhythmias, heart failure, heartworm disease, hypertension - Ophthalmology: Gaucoma, cataracts, uveitis, corneal disease, ocular surgery - Allergic disease: Allergic dermatitis, food allergies, flea allergy, and allergic gastrointestinal and respiratorendocrine skin disease - Gastroenterology: Chronic vomiting and / or diarrhea, inflammatory bowel disease (IBD), stomach ulcers / gastritis, colitis, pancreatic disorders, liver disease, protein - losing enteropathy - Respiratory disease: Feline asthma, canine chronic bronchitis, upper respiratory viral disease, pleural effusion, laryngeal paralysis - Cardiology: Heart murmurs and arrhythmias, heart failure, heartworm disease, hypertension - Ophthalmology: Gaucoma, cataracts, uveitis, corneal disease, ocular surgery - Allergic disease: Allergic dermatitis, food allergies, flea allergy, and allergic gastrointestinal and respiratory disease

Dr Jean W Dodds, writing in US Dog World, March, 1995, (16) states: «Immune — suppressant viruses of the retrovirus and parvovirus classes have recently been implicated as causes of bone marrow failure, immune - mediated blood diseases, haematologic malignancies (lymphoma and leukemia), dysregulation of humoral and cell - mediated immunity, organ failure (liver, kidney) and autoimmune endocrine disorders — especially of the thyroid gland (thyroiditis), adrenal gland (Addison's disease) and pancreas (diabetes).

The endocrine system includes the adrenal glands, thyroid gland, parathyroid gland, pituitary gland and specialized cells in the pancreas called the Islets of Langerhans.

There are not two distinct sections of the pancreas responsible for these functions; rather, the endocrine and exocrine related cells are diffused throughout the entire organ.

* Diseases of the endocrine system, such as Cushing's disease, hyperthyroidism, and diabetes * Chronic kidney disease * Central nervous system disorders * Certain medications * Diabetes Mellitus * Red Blood Cell Over Production (Polycythemia) * Some cases of high blood pressure have no known cause