Sentences with phrase «of endogenous antioxidants»

The Adaptive Stress Response includes well over 100 cytoprotective proteins that participate in production of endogenous antioxidants, DNA & protein repair, damaged protein removal, toxin export, metal chelation, inflammation inhibition, or are themselves antioxidants.

For one, obtainable tissue concentrations are only 2 - 4 % those of endogenous antioxidants (uric acid, glutathione, bilirubin).

For one, obtainable tissue concentrations are only 2 - 4 % those of endogenous antioxidants like uric acid, glutathione, and bilirubin.

The cells reacted to this by stepping up their production of endogenous antioxidants, such as the enzymes superoxide dismutase [SOD] and catalase.

Molecular hydrogen appears to stimulate the production of endogenous antioxidants via the Nrf2 Pathway, meaning it up - regulates the body's own antioxidant system.

Not exact matches

Thioredoxin - 1 (Trx1) is an endogenous antioxidant protein important for redox regulation and participates in the regulation of apoptosis through the inhibition of apoptosis signal - regulating kinase - 1 (Ask - 1).

Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.

Food science: - Sulfer is one of the most abundant mineral elements in the human body - Sulfer is required for the synthesis of glutathione, one of our endogenous (we make our own) antioxidants — an antioxidant that neutralizes free radicals, helps control blood pressure and inflammation, and helps the liver process toxins - Sulfur is essential for Taurine synthesis — taurine is essential to our Central nervous system and the workings of our cardiovascular system - Sulfur helps bind the amino acid chains that form insulin.

[29] production of a vital endogenous antioxidant that protects against the kind of oxidative stress that leads to diabetic complications: http://www.ncbi.nlm.nih.gov/pubmed/17192491

GSH, being an endogenous antioxidant, has the advantage of working within the cells of our body, not outside.

It is one of the body's endogenous antioxidants, along with superoxide dismutase (SOD), CoEnzyme Q10 (CoQ10), alpha lipoic acid and Catalase.

All these substances can help prevent free radical damage, and together with the body's natural antioxidants (endogenous), they are the main source of protection for muscles and other tissues.

Alpha - lipoic acid, another powerful endogenous antioxidant, increases glutathione production in the body, as does the sleep hormone melatonin — which stimulates production of the antioxidant enzyme glutathione peroxidase.

And it is the job of our body's endogenous antioxidants to quench them.

Harm to DNA from free radicals is due to both endogenous factors like a lack of antioxidants and environmental factors like diet, exercise, stress, pollution and even sun exposure (12,13,14).

Moreover, reactive nitrogen and oxygen species (RNOS) are used extensively in cellular signalling, and cells adaptively regulate endogenous antioxidants on short time scales to respond to deletorious spikes of RNOS faster than we could ever achieve with dietary antioxidants.

Mussels are one of the better sources of manganese, a mineral that helps oppose iron overload and figures prominently in the production of a vital endogenous antioxidant that protects against the kind of oxidative stress that leads to diabetic complications (whew!).

A growing body of evidence indicates that consuming large quantities of antioxidants like vitamin C, E, and β - carotene can interfere with the body's endogenous antioxidant system.

Most anti-inflammatory substances thwart inflammation in one of the following ways: by neutralizing the free radicals that cause inflammation (most «anti-inflammatory» foods work their magic through this antioxidant activity), or by stopping the endogenous production inflammatory chemicals (this is how ibuprofen, aspirin, and other non-steroidal anti-inflammatory drugs (NSAID's) work).

Apparently, alcohol is not only metabolized to detrimental compounds like acetaldehyde, but also facilitates the endogenous production of — believe it or not — hydroxytrosol (yes, that highly beneficial antioxidant phenol found in olives and olive oil!).

Antioxidants can be either endogenous (originating within the body) or exogenous (originating outside of the body, via nutritional habits or supplementation, for example).