Sentences with phrase «of endometrial cancer»

This risk of endometrial cancer increases with the number of and length of time between missed periods.

«Oral contraceptives have prevented about 200,000 cases of endometrial cancer in the last decade.»

Estrogen dominance is responsible for the majority of breast cancers and is the only known cause of endometrial cancer in women.

Uterine carcinosarcoma is one of the deadliest forms of endometrial cancer.

A study published this week in PLOS Medicine suggests that epigenetic modification of the HAND2 gene plays a critical role in the development of endometrial cancer.

Women who had PCOS also had a higher rate of endometrial cancer, or cancer of the lining of the uterus.

«In this study, an inverse association was observed between the risk of endometrial cancer for women with an MMR gene mutation and later age of menarche, increased parity, and use of hormonal contraceptives.

The findings reveal that every 5 years of oral contraceptive use reduces the risk of endometrial cancer by about a quarter.

Between 2 percent and 5 percent of all endometrial cancer cases are associated with a hereditary susceptibility to cancer, mainly Lynch syndrome, which is caused by a germline mutation in one of the DNA mismatch repair (MMR) genes.

«The majority of endometrial cancers are estrogen - driven,» said Ward.

Moreover, analysis of HAND2 methylation in endometrial secretions collected from women with postmenopausal bleeding (which can be a symptom of endometrial cancer) accurately identified individuals with early stage cancer.

«We hoped,» says Klonisch, «that researchers could use them to gain novel insights into important aspects of reproductive biology and the evolution of endometrial cancer.»

These results suggest that the amount of hormones in the lower - dose pills is still sufficient to reduce the incidence of endometrial cancer, say the authors.

Educate CEP awardees in up - to - date principles of endometrial cancer biology and clinical care with an emphasis on translational science.

With a complete analysis of the study's findings, investigators have identified four novel genomic - based subtypes of endometrial cancer, which may set the stage for new diagnostic and treatment approaches.

Investigators supported under this Program will develop new innovative ideas that can improve prevention, diagnosis or treatment of endometrial cancer.

We also observed a reduction of 26 % in the risk of endometrial cancer among coffee drinkers, compared with nondrinkers, and of > 30 % among heavy coffee drinkers.

The researchers found that later age at menarche (first menstrual cycle, age 13 or older), parity (has had one or more live births), and hormonal contraceptive use (for one year or longer) were associated with a lower risk of endometrial cancer.

Researchers from the Collaborative Group on Epidemiological Studies on Endometrial Cancer estimate that in the past 50 years (1965 - 2014) about 400000 cases of endometrial cancer have been prevented by oral contraceptive use in high - income countries, including about 200000 in the last decade (2005 - 2014).

Tumor - targeting nanoparticles loaded with a drug that makes cancer cells more vulnerable to chemotherapy's toxicity could be used to treat an aggressive and often deadly form of endometrial cancer, according to new research...

On the other hand, female - specific conditions attributable to overweight include infertility, an increased incidence of breast cancer, and higher rates of endometrial cancer.

The PapSEEK test accurately detected 81 percent of endometrial cancers and 33 percent of ovarian cancers, according to the study.

By contrast, in more than 90 % of endometrial cancers, the gene has undergone hypermethylation, an epigenetic modification that doesn't change its DNA sequence but renders it inactive.

«Estimating from various studies that looked at increasing BMI and endometrial cancer risk, a woman with a Body Mass Index (BMI) of 40 would have approximately eight times greater risk of endometrial cancer than someone with a BMI of 25,» said first author Kristy Ward, MD, the senior gynecologic oncology fellow in the Department of Reproductive Medicine at UC San Diego School of Medicine.

«Further work is needed to define the role of bariatric surgery in cancer care and prevention, but we know that women with endometrial cancer are more likely to die of cardiovascular causes than they are of endometrial cancer.

While not all people with Lynch syndrome will develop cancer, a person who has the mutation is more likely to get certain types of cancer, including an 80 percent higher risk of colorectal cancer and a 60 percent higher risk of endometrial cancer.

That can be especially risky when a woman takes estrogen without enough progesterone, an imbalance that puts women at increased risk of endometrial cancer.

«Association between genetic condition, hormonal factors, and risk of endometrial cancer.»

For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study in the July 7 issue of JAMA.

According to study author Dr Naomi Allen, also from the University of Oxford, UK, «The existing evidence suggests that medium - to - long - term use of oral contraceptives (ie, for 5 years or longer) results in substantially reduced risk of endometrial cancer.

In a pilot study, the «PapGene» test accurately detected 100 percent (24 of 24) of endometrial cancers and 41 percent (9 of 22) ovarian cancers.

Having too much estrogen for an extended period of time increases your risk of endometrial cancer.

The first Premarin scare in the 70s, where it was noted that women who were on Premarin had a higher risk of endometrial cancer, was the first time that Premarin fell off the stage as the panacea for everything.

In addition, tamoxifen increases the risk of endometrial cancer and blood clots, including fatal blood clots in the lung.

Available since FDA approval in 1942, Premarin has caused an estimated 15,000 cases of endometrial cancer, representing the largest epidemic of serious iatrogenic disease ever reported.

Because obesity is known to increase a woman's risk of endometrial cancer by 200 percent, a team of researchers led by oncologist Leena Hilakivi - Clarke of Georgetown Lombardi Comprehensive Cancer Center in Washington, D.C., decided to examine the development of endometrial cancer in obese mice to that in non-obese mice.

A report published today (Sept. 21) in the journal Cancer Prevention Research demonstrates that, in the case of endometrial cancer, it could help to focus on specific subgroups in the population.