The process
of endothelial damage, vasoconstriction, increased flow velocity, and local ischemia is a vicious cycle.
To obtain a viable donor of a Descemet membrane endothelium disc, we modified the Descemet membrane stripping technique and monitored the percentage
of endothelial damage to the donor tissue preparation.
Not exact matches
This happens because the loss
of blood flow in a vessel causes the local oxygen level to drop, which stimulates local production
of vascular
endothelial growth factor, or VEGF, a protein which in most tissues causes the growth
of new blood vessels to repair
damage.
Researchers from the UNC School
of Medicine have discovered that cells called fibroblasts, which normally give rise to scar tissue after a heart attack, can be turned into
endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions
of the heart, thus greatly reducing the
damage done following heart attack.
Professor Takao Hamakubo's group at the Department
of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology (RCAST), have shown that PTX3 forms strong bonds with histones and partially unfolds, leading to a disordered coaggregation
of histone and PTX3 and protecting human
endothelial cells from
damage.
The force
of that blood flow helps keep the cells that line the blood vessels, called
endothelial cells, healthy; when blood flow is disrupted, such as during surgical procedures or a stroke, the vessels start to leak, which can cause a host
of inflammatory responses that lead to cell
damage and disease.
This happens because the loss
of blood flow in a blood vessel causes the local oxygen level to drop, which stimulates local production
of vascular
endothelial growth factor, or VEGF, a protein that in most tissues causes the growth
of new blood vessels to repair
damage.
Conclusion: We modified the technique
of Melles and obtained a sheet
of Descemet membrane and endothelium with minimal
endothelial damage and with no remaining stroma observed.
If we understand the special features
of insulin resistance in
endothelial cells, we may be able to find more effective treatments against artery
damage and cardiovascular disease in people with diabetes.»
Results: Forty
of 48 endothelium - Descemet membrane preparations (83.3 %) were complete peels with minimal
endothelial damage.
We will combine methods from the fields
of immunology, developmental biology and angiogenesis to understand in vivo the development and lineage - specific function (s)
of resident macrophages, thereby opening new venues
of research into the interaction between macrophages and
endothelial cells in response to tissue
damage.
Additionally, there was no
damage to the
endothelial cells
of untargeted organs.
At the same time, the protein Vascular
Endothelial Growth Factor (VEGF) stimulates blood supply for the
damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the
damaged cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair
of the
damaged tissue.
Researchers at the University
of Palermo in Italy found that the betalains contained in prickly pears appears to protect the
endothelial cell walls
of blood vessels from oxidative
damage by free radicals.
The patient example here used to discredit the virtues
of the plant based intervention approach would have likely showed massive
endothelial damage from the decades
of high animal protein and artery injuring foods, in fact the plant based intervention at the late stage
of his chronic illness may have actually improved blood work and perhaps added some time to this patients life although it is not mentioned here.
Points to make: soy protein isolate and other highly processed modern soy protein products are not safe and have no long history
of use in the food supply; studies published since 1999 undermine the credibility
of — and conclusions drawn — from key studies evaluated by the FDA when it approved the health claim in 1999; recent studies show that soy can contribute to or cause heart disease, including
endothelial damage (especially in women), heart arrhythmias and cardiomyopathy, an increasingly prevalent condition that affects 1 in 500 Americans.
For example, I recall exotoxins from animal products being a causative factor for inflammation and the corresponding cascading
of events with
endothelial damage, which is then spackled over with cholesterol as a repair mechanism.
In this prospective, open and non-randomized study, the effect
of alpha - lipoic acid on the progression
of endothelial cell
damage and the course
of diabetic nephropathy, as assessed by measurement
of plasma thrombomodulin and urinary albumin concentration (UAC), was evaluated in 84 patients with diabetes mellitus over 18 months.
Effect
of Alpha - lipoic Acid on the Progression
of Endothelial Cell
Damage and Albuminuria in Patients with Diabetes Mellitus: An Exploratory Study Diabetes Res Clin Pract 2001 (Jun); 52 (3): 175 — 183 Oxidative stress plays a central role in the pathogenesis and progression
of late microangiopathic complications (diabetic nephropathy) in diabetes mellitus.
/ consuming Animal proteins cause numerous proteins as it is not designed for us / may be designed to grow that animal at a rate much faster than we are designed for / and also feeds the growth
of Cancer cells /
damages the
Endothelial cells / ala Dr. Esselstyn and others.
We know that infection and bacterial toxins are one source
of this inflammation and
endothelial damage.
While you promote healthy fats for brain, neurological and general health; Dr. Esselstyn suggests that all oils
damage the
endothelial lining
of our blood vessels... I am interested in adopting your suggestions, and have read «Grain Brain,» but remain a little apprehensive
of embracing healthy fats... how would you address Dr. Esselstyn specifically?