Sentences with phrase «of epidemic potential»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

That being said, he says he has been getting a lot of tenant interest on the phone, but it seems there has been an epidemic of «flat tires» that leads to a text message from the potential tenant letting him know they are not going to make the appointment — the last one today was outside at the curb when she sent the text:O.

Don't forget as well the potential epidemic of nuclear proliferation as other nations attempt to adjust to and defend themselves against Bush's preventive wars, while our own already staggering nuclear arsenal expands toward first - strike primacy and we expend unimaginable billions on futuristic ideas for warfare in outer space.

The researchers were surprised with the findings: «This was a major surprise for us — that soybean oil is causing more obesity and diabetes than fructose — especially when you see headlines everyday about the potential role of sugar consumption in the current obesity epidemic.

Bullying has reached epidemic proportions and, according to at least forty years of psychological, psychiatric, sport, and neuroscientific research, is directly correlated with addiction, low self - esteem, depression, failure to reach potential, self - harm, athletes quitting sports, eating disorders, chronic illness and suicide.

The Institute of Medicine recognized the potential for food and beverage sales in youth sport to contribute to the childhood obesity epidemic and recommended that programs encourage the sale of healthier options in youth sport venues.

The governor, who is considered a potential Democratic presidential candidate in 2020, also plans to take on some of the leading national issues of the day - sexual harassment, climate change, the opioid epidemic, terrorism and reforming the criminal justice system.

They discuss the obesity epidemic, the implementation of health care exchanges, hydrofracking's potential health impacts, and flu shots.

In the course of her doctoral dissertation, Jing Helmersson has developed two mathematical models to calculate the potential of the dengue epidemic and dengue mosquito proliferation globally, with focus in Europe.

And while the potential end of the epidemic is no doubt positive, it does raise issues for vaccine development, adds Professor Ferguson: «If our projections are correct, cases will have dropped substantially by the end of next year, if not sooner.

She's Margaret Hamburg, 53, the New York City health commissioner in the 1990s and later an official at the Department of Health and Human Services, where she specialized in bioterrorism and planning a response to a potential flu epidemic.

In order to project the impact of proposed cutbacks to U.S. - funded programs in South Africa, which has the greatest prevalence of HIV infection of any country, and the west African nation of Côte d'Ivoire, which has a different kind of epidemic and a different level of foreign aid dependency, the researchers used a widely - published mathematical model along with epidemiologic and cost data from each country to project the outcomes of potential programmatic responses.

The WHO's declaration of a global public health emergency is the third ever made under international regulations enacted in 2007; the first came in 2009 during the H1N1 influenza epidemic and the second in May, warning of the potential for international spread of the polio virus.

«The scope of the epidemic and the fact that cases were imported into the United States and Europe reinforces the importance of these viruses as pathogens and public health threats, and drives home for us the idea that we need to be looking really seriously at ways we can translate our basic science into potential therapeutics.

Lowe says that the study also demonstrates the potential value of incorporating climate information in the public health decision - making process not only in Ecuador but also in any epidemic - prone region, impacted by El Nino events.

Given that outbreaks of yellow fever in urban settings have the potential for rapid spread and that significant yellow fever epidemics are ongoing in Angola, DRC and Uganda, a range of options for response by EU / EEA Member States are presented in the updated rapid risk assessment.

The global spread of dengue virus (DENV) infections has increased viral genetic diversity, some of which appears associated with greater epidemic potential.

Global epidemics, global warming, and environmental toxins are here now, but it is not clear that any of them have the potential to wipe out humanity.

The potential for epidemics to occur in parts of Africa and the Asia - Pacific region is particularly concerning given that the vast numbers of people who could be exposed to Zika virus are living in environments where health and human resources to prevent, detect, and respond to epidemics are limited.

The potential epidemic was eventually contained (with the help of cold fall temperatures), but the long - term costs of the victory may never be known.

He says that researchers could one day spare scores of lives and nip potential epidemics in the bud by whipping up a treatment within a month from natural antibodies that survivors developed against the threatening disease.

«This potential mismatch in timing could significantly diminish the usefulness of vaccination for mitigating the epidemic and could place many at risk of serious disease,» predicted the President's Council of Advisors on Science and Technology in a report the White House released on 24 August.

There was a strong possibility that the epidemic had peaked, but there were still at least a dozen people around Yambuku who were critically ill, with almost no provision for quarantine, so a strong potential for flare - ups or another big wave of infection remained.

The stories of Father Carlos and Dr. N'goy, the District Medical Officer who had first identified the epidemic, the reports at the Bumba hospital, the evident fear of the pilots and the townspeople of Bumba and their desperate attempts to flee the town... the apparent virulence of this disease, the high mortality — put together with the poverty and poor organization that characterized Zaire and the potential for contagion in Kinshasa — added up to a picture that Joel Breman, a CDC senior epidemiologist, summarized as «potentially the most deadly epidemic of the century.»

To assess one potential cause of the sleeplessness epidemic, respondents were also asked whether they used a computer, smartphone or tablet in the two hours before going to bed.

For sub-Saharan Africa (where heterosexual sex is primarily responsible for the HIV epidemic), circumcision has the potential to dramatically reduce the toll of the virus, which WHO estimates of up to 5.7 million new infections and three million deaths averted over the next 20 years.

Buprenorphine is a critical part of treatment for the growing epidemic of opioid abuse — but also carries the potential for misuse and diversion.

«This RMSF epidemic largely affects children and young adults who were previously healthy, who would otherwise have the most potential to contribute economically to society,» the researchers reported in their study published in The American Journal of Tropical Medicine and Hygiene.

«Recent events have taught the global community that promising candidate countermeasures for emerging infectious diseases, like MERS, need to be advanced early in order to prevent or respond to the potential of a growing epidemic.»

«The advantage of the current study is that it provides a framework for assessing the potential epidemic impact that might occur in environments that lack sufficient data,» said the study's co-author Mike Tildesley from the University of Warwick.

To understand these changes and to anticipate the future of the virus, the exact distribution, genetic diversity, transmission routes, and future epidemic potential of CHIKV require further assessment.

The Neitzes are internationally recognized for developing a potential gene therapy cure for color blindness and are among the world's thought leaders on genetic and environmental factors that may be influencing a global epidemic of myopia...

Their projections illustrate the potential burden of the U.S. obesity epidemic if current trends continue.

Cachexia has the potential to be under recognized in the face of the obesity epidemic as muscle mass loss is harder to detect in larger individuals.

Cellulite Suspects: The lineup of potential culprits responsible for the modern cellulite epidemic.

Johnson RJ, Segal MS, Sautin Y, et al: Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.

It has tremendous potential to impact the modern epidemic of obesity and many other diseases yet to be studied.

It takes place in the early 1990s, following a group of grassroots activists in Paris trying to combat public and bureaucratic indifference with regard to the AIDS epidemic, for which potential pharmaceutical remedies are being sidetracked by sociopolitical obstacles.

«I would argue that school administrators who have banned tag because of the potential injury to the child are very misdirected in their thinking,» says Rhonda Clements, Ed.D. «We are reaching an epidemic of childhood obesity in the U.S., and we should not quash the child's natural desire to play vigorously with peers.

«Research has demonstrated that programs like Pete's Pet Posse have the potential to lessen this anxiety epidemic and improve the quality of life of our campus family.»

Governments all over the world are quarantining millions of infected birds and putting them to death, to hold off a potential epidemic.

Uses analyses at national and state scales to examine a suite of climatic and intrinsic drivers of continental - scale West Nile virus epidemics, including an empirically derived mechanistic relationship between temperature and transmission potential that accounts for spatial variability in vectors

These hazards have the potential to cause coastal erosion, landslides, mudslides, epidemics, and the movement and spread of toxic substances and volcanic material.