Sentences with phrase «of epigenetic marks»

In order to lay down the proper pattern of epigenetic marks, for example, embryos need to get the raw ingredients from their mothers.

To that end, they examined in mouse embryos the global distribution of an epigenetic mark known to play a critical role in regulating the activity of genes.

«We note that there are two subgroups of breast tumors by epigenome: one which we have called Epi - Basal, characterized by loss of epigenetic marks causing breakage of chromosomes and the other that we have called Epi - Luminal B, that presents epigenetic inactivation of genes that should protect us from cancer and these altered cells can no longer do it.»

Images of C. elegans embryos show inheritance and transmission of an epigenetic mark.

The specific pattern of epigenetic marks in a cell type specifies identity and this epigenetic control is vital to what makes our cells different, for example a skin cell from a liver cell, when they all contain the same genetic instructions.

Explore structural mechanisms underlying recognition of histone tails by the readers, writers and erasers of epigenetic marks.

H3K9ac and H3K56ac are enriched at the promoters of genes required to maintain pluripotency, and loss of these epigenetic marks correlates with stem cell differentiation.

The researchers then analyzed the DNA to examine the degree of an epigenetic mark called methylation, a chemical tag on genes related to whether they're «turned on» or «off.»

If mothers don't get enough folate, their unborn children may lay down an impaired pattern of epigenetic marks that causes their genes to malfunction.

A team led by Dr Gavin Kelsey in the Babraham Institute and colleagues in Dresden and Munich studied a protein called MLL2 and discovered how it produces a distinctive pattern of epigenetic marks that are needed for egg cell stasis.